Systematic DC/AC Performance Benchmarking of Sub-7-nm Node FinFETs and Nanosheet FETs

In this paper, we systematically evaluate dc/ac performances of sub-7-nm node fin field-effect transistors (FinFETs) and nanosheet FETs (NSEETs) using fully calibrated 3-D TCAD. The stress effects of all the devices were carefully considered in terms of carrier mobility and velocity averaged within the active regions. For detailed AC analysis, the parasitic capacitances were extracted and decomposed into several components using TCAD RF simulation platform. FinFETs improved the gate electrostatics by decreasing fin widths to 5 nm, but the fin heights were unable to improve RC delay due to the trade-off between on-state currents and gate capacitances. The NSEETs have better on-state currents than do the FinFETs because of larger effective widths (W-eff) under the same device area. Particularly p-type NSEETs have larger compressive stress within the active regions affected by metal gate encircling all around the channels, thus improving carrier mobility and velocity much. On the other hand, the NSEETs have larger gate capacitances because larger W-eff increase the gate-to-source/drain overlap and outer-fringing capacitances. In spite of that, sub-7-nm node NSEETs attain better RC delay than sub-7-nm node as well as 10-nm node FinFETs for standard and high performance applications, showing better chance for scaling down to sub-7-nm node and beyond.11Ysciescopu

Bottom oxide Bulk FinFETs Without Punch-Through-Stopper for Extending Toward 5-nm Node

Structural advancements of 5-nm node bulk fin-shaped field-effect transistors (FinFETs) without punch-through-stopper (PTS) were introduced using fully calibrated TCAD for the first time. It is challenging to scale down conventional bulk FinFETs into 5-nm technology node due to the sub-fin leakage increase. Meanwhile, bottom oxide deposition after anisotropic etching for source/drain (S/D) epi formation prevents the sub-fin leakage effectively even without the PTS doping, thus achieving better gate-to-channel controllability. Bottom oxide FinFETs also have smaller gate capacitances than do conventional FinFETs because the parasitic capacitances decrease by smaller S/D epi separated from the bottom Si layer, which reduces junction and outer-fringing capacitances. But smaller S/D epi decreases the stresses along the channel direction, and the effective widths decrease by the bottom oxide layer blocking the current paths at the bottom side of fin channels. Furthermore, increase of the interconnect resistance and capacitance parasitics down to 5-nm node diminishes the improvements of total delays as the interconnect wire length increases greatly. In spite of these drawbacks, 5-nm node bottom oxide FinFETs achieve smaller total delays than do the 7-nm node conventional FinFETs, especially for low-power applications, thus promising for the scalability of bulk FinFETs along with simple and reliable process by avoiding PTS step.11Ysciescopu

Correlation of Serum Biomarkers and Magnetic Resonance Spectroscopy in Monitoring Disease Progression in Patients With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes Due to mtDNA A3243G Mutation

Background: Analysis of serum biomarkers and magnetic resonance spectroscopy (MRS) are useful for monitoring disease progression in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS). We evaluated the correlation of serum biomarkers and MRS parameters during changes associated with stroke-like episodes.Methods: In 13 symptomatic MELAS patients carrying the A3243G mutation, we retrospectively obtained 207 voxels from 41 MRS studies, which were divided into three groups according to the temporal association with stroke-like episodes. The MRS NAA/Cr, Cho/Cr, NAA/Cho ratios, the presence of a lactate peak, serum biomarkers, serum lactate level and the pyruvate (Lac/Pyr) ratio were determined.Results: In regions with acute infarcts, the severity of serum Lac/Pyr and that of the MRS lactate peak (P = 0.0007) correlated; serum lactate (P = 0.02), severity of elevated serum lactate (P = 0.04), and serum Lac/Pyr (P = 0.02) correlated weakly. In previously infarcted regions, the severity of the MRS lactate peak and serum Lac/Pyr (P = 0.03), as well as the severity of serum Lac/Pyr (P = 0.02) were weakly correlated. In structurally normal regions, we found a weak to moderate negative correlation between serum lactate and MRS NAA/Cr (P = 0.008), and between the severity of elevated serum lactate and MRS NAA/Cr (P = 0.002) as well as MRS NAA/Cho (P = 0.02).Conclusions: MRS parameters correlate with specific serum biomarkers, and are useful for monitoring changes in brain metabolites, particularly as related to stroke-like episodes

Whole-brain imaging with receive-only multichannel top-hat dipole antenna RF coil at 7 T MRI

This work investigates the construction and performance of an eight-channel top-hat dipole receiver RF coil with a capacitive plate to increase the longitudinal whole-brain coverage and receiver sensitivity gain in the brain at 7 T MRI. The construction method for top-hat dipole-based receiver RF coil by adjusting the length and structure corresponding to each channel consists of tuning, matching, balun, and detuning circuitry. Electromagnetic simulations were analyzed on a 3-D human model to evaluate B1+ efficiency and specific absorption rate deposition. Coil performance was evaluated in the human head imaging in vivo. EM simulation results indicated a higher B1− sensitivity in the brain and z-directional coverage of the proposed eight-channel receiver RF coil. The MR images were acquired with an identical field of view showing the receiver coverage improvement in the brain when capacitive plates are used. The MR images also show the clear visibility of the complete set of the cervical vertebrae as well as the spinal cord. The acquired MRI results demonstrate the capability of the proposed RF coil to increase the receiver coverage in the longitudinal direction. Moreover, the B1+ efficiency, as well as receiver sensitivity in the brain, can be substantially improved with the use of multilayered capacitive plates of proper shape and size in conjunction with an RF coil