Text2Action: Generative Adversarial Synthesis from Language to Action

In this paper, we propose a generative model which learns the relationship between language and human action in order to generate a human action sequence given a sentence describing human behavior. The proposed generative model is a generative adversarial network (GAN), which is based on the sequence to sequence (SEQ2SEQ) model. Using the proposed generative network, we can synthesize various actions for a robot or a virtual agent using a text encoder recurrent neural network (RNN) and an action decoder RNN. The proposed generative network is trained from 29,770 pairs of actions and sentence annotations extracted from MSR-Video-to-Text (MSR-VTT), a large-scale video dataset. We demonstrate that the network can generate human-like actions which can be transferred to a Baxter robot, such that the robot performs an action based on a provided sentence. Results show that the proposed generative network correctly models the relationship between language and action and can generate a diverse set of actions from the same sentence.Comment: 8 pages, 10 figure

Pilot KaVA monitoring on the M87 jet: confirming the inner jet structure and superluminal motions at sub-pc scales

We report the initial results of our high-cadence monitoring program on the radio jet in the active galaxy M87, obtained by the KVN and VERA Array (KaVA) at 22 GHz. This is a pilot study that preceded a larger KaVA-M87 monitoring program, which is currently ongoing. The pilot monitoring was mostly performed every two to three weeks from December 2013 to June 2014, at a recording rate of 1 Gbps, obtaining the data for a total of 10 epochs. We successfully obtained a sequence of good quality radio maps that revealed the rich structure of this jet from <~1 mas to 20 mas, corresponding to physical scales (projected) of ~0.1-2 pc (or ~140-2800 Schwarzschild radii). We detected superluminal motions at these scales, together with a trend of gradual acceleration. The first evidence for such fast motions and acceleration near the jet base were obtained from recent VLBA studies at 43 GHz, and the fact that very similar kinematics are seen at a different frequency and time with a different instrument suggests these properties are fundamental characteristics of this jet. This pilot program demonstrates that KaVA is a powerful VLBI array for studying the detailed structural evolution of the M87 jet and also other relativistic jets.Comment: 10 pages, 9 figures, accepted for publication in PAS

Suppression of CFTR-mediated Cl- Secretion of Airway Epithelium in Vitamin C-deficient Mice

Hyperoxic ventilation induces detrimental effects on the respiratory system, and ambient oxygen may be harmful unless compensated by physiological anti-oxidants, such as vitamin C. Here we investigate the changes in electrolyte transport of airway epithelium in mice exposed to normobaric hyperoxia and in gulonolacton oxidase knock-out (gulo[-/-]) mice without vitamin C (Vit-C) supplementation. Short-circuit current (Isc) of tracheal epithelium was measured using Ussing chamber technique. After confirming amiloride-sensitive Na+ absorption (ΔIsc,amil), cAMP-dependent Cl- secretion (ΔIsc,forsk) was induced by forskolin. To evaluate Ca2+-dependent Cl- secretion, ATP was applied to the luminal side (ΔIsc,ATP). In mice exposed to 98% PO2 for 36 hr, ΔIsc,forsk decreased, ΔIsc,amil and ΔIsc,ATP was not affected. In gulo(-/-) mice, both ΔIsc,forsk and ΔIsc,ATP decreased from three weeks after Vit-C deprivation, while both were unchanged with Vit-C supplementation. At the fourth week, tissue resistance and all electrolyte transport activities were decreased. An immunofluorescence study showed that the expression of cystic fibrosis conductance regulator (CFTR) was decreased in gulo(-/-) mice, whereas the expression of KCNQ1 K+ channel was preserved. Taken together, the CFTR-mediated Cl- secretion of airway epithelium is susceptible to oxidative stress, which suggests that supplementation of the antioxidant might be beneficial for the maintenance of airway surface liquid

Cellular plasticity and immune microenvironment of malignant pleural effusion are associated with EGFR-TKI resistance in non-small-cell lung carcinoma

Malignant pleural effusion (MPE) is a complication of lung cancer that can be used as an alternative method for tissue sampling because it is generally simple and minimally invasive. Our study evaluated the diagnostic potential of non-small-cell lung carcinoma (NSCLC)-associated MPE in terms of understanding tumor heterogeneity and identifying response factors for EGFR tyrosine kinase inhibitor (TKI) therapy. We performed a single-cell RNA sequencing analysis of 31,743 cells isolated from the MPEs of 9 patients with NSCLC (5 resistant and 4 sensitive to EGFR TKI) with EGFR mutations. Interestingly, lung epithelial precursor-like cells with upregulated GNB2L1 and CAV1 expression were enriched in the EGFR TKI-resistant group. Moreover, GZMK upregulated transitional effector T cells, and plasmacytoid dendritic cells were significantly enriched in the EGFR TKI-resistant patients. Our results suggest that cellular plasticity and immunosuppressive microenvironment in MPEs are potentially associated with the TKI response of patients with EGFR-mutated NSCLC

Biodiversity Agenda Congruent with ‘One Health’: Focusing on CBD, FAO, and WHO

The decrease in biodiversity occurs across national borders and has mutual influences on food and health. In this study, we analyzed the links and relationships between the decisions made by the Food and Agriculture Organization (FAO) of the United Nations, the World Health Organization (WHO), and the Convention on Biological Diversity (CBD)—the highest decision-making bodies in each field—from 1994 to 2018. We aimed to determine how each regime related to the decisions of others and identify the critical agendas that mediate the three regimes. Consequently, critical agendas, including agricultural biodiversity, taxonomy, traditional knowledge, access and benefit sharing, antimicrobial resistance, and marine biodiversity, were observed. In the order of degree centrality, the top six agendas were discussed in terms of the cooperation history of ‘One Health’ and its implications

Improvements in the scanning long-wave optical test system

The Scanning Long-wave Optical Test System (SLOTS) is a slope measuring deflectometry system that provides accurate measurements on ground surfaces. As it uses a thermal source, we can measure an optic during the grinding phase which allows us to correct figure errors when material removal is much faster. We have made improvements in SLOTS, such as the step-and-stare method, the ceramic rod, and the Gaussian fitting processing software, so that this system supports higher accuracy and resolution. As a result, SLOTS is an optical testing system that covers a huge portion of the fabrication process from the grinding to the figuring. It is a complementary solution for other metrology systems such as the laser tracker, SCOTS, and null interferometry. SLOTS can reduce the manufacturing time by producing ground aspheres that have low errors of the surface figure when polishing begins.This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

Assessing the Suitability of the Flood Defense Policy of Republic of Korea for Risk Reduction in Local Rivers

This study examines whether the fluvial flood defense system of Korea is appropriate for risk reduction. Using spatial socioeconomic data and remote sensing, we estimated the potential economic damage that can be caused by the flooding of local streams and rivers along the Nakdong River (the longest river in Korea). For the analysis, a river risk map including return periods (50, 80, 100, and 200 years) and spatial inventories (residential, agricultural, industrial assets, and human lives) was employed to determine flood-prone areas and assess the damage within the inundation areas. A quantitative flood analysis was conducted using an object-based method to estimate the expected annual damage. We then compared the estimated damage for each tributary within the designed return periods and found no correlation. Numerous tributaries with low-defense targets were considered high-risk, while those with high-defense targets were assessed as low-risk. The dataset used in this study covered four damage categories. Among them, flood damage to residential assets appeared to have the highest value, whereas flood damage to industrial assets had the lowest value. The results demonstrate that the Korean government needs to tailor its flood defense policy based on quantitative risk assessments to effectively manage flood risks, especially given the increasing risk of climate change