Spinal nerve segmentation method and dataset construction in endoscopic surgical scenarios

Endoscopic surgery is currently an important treatment method in the field of spinal surgery and avoiding damage to the spinal nerves through video guidance is a key challenge. This paper presents the first real-time segmentation method for spinal nerves in endoscopic surgery, which provides crucial navigational information for surgeons. A finely annotated segmentation dataset of approximately 10,000 consec-utive frames recorded during surgery is constructed for the first time for this field, addressing the problem of semantic segmentation. Based on this dataset, we propose FUnet (Frame-Unet), which achieves state-of-the-art performance by utilizing inter-frame information and self-attention mechanisms. We also conduct extended exper-iments on a similar polyp endoscopy video dataset and show that the model has good generalization ability with advantageous performance. The dataset and code of this work are presented at: https://github.com/zzzzzzpc/FUnet .Comment: Accepted by MICCAI 202

Hand Dexterity Recovery Capacity for Degenerative Cervical Myelopathy With Varying Levels of Impairment: A Prospective 1-Year Follow-up Study

Objective This study aimed to elucidate the hand function recovery capacity of degenerative cervical myelopathy (DCM) patients with different severities of hand dexterity impairment. Methods Hand functional outcome measures such as the 10-second grip and release (10s-G&R) test, modified Japanese Orthopaedic Association (mJOA) upper extremity score and Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire (JOACMEQ) upper extremity function were collected before surgery and at the 1-year follow-up. A total of 102 DCM patients were categorized into mild, moderate and severe group based on the preoperative 10s-G&R test result. Hand functional parameters were compared across the 3 groups. Multivariate linear regression was conducted to explore predictive factors. Receiver operating characteristic curve analysis was performed to assess the predictive efficacy of the preoperative 10s-G&R test and establish the cutoff value for incomplete recovery of hand dexterity. Results At the 1-year follow-up, significant improvements were observed in all hand functional parameters across all 3 groups. However, the incomplete recovery rates of the mild, moderate, severe groups were 26.67%, 46.88%, and 57.50%, respectively (p < 0.05). Multivariate regression revealed that preoperative 10s-G&R test result, age, Hoffmann sign, duration of symptom, and mJOA Upper score serve as significant predictors for postoperative 10s-G&R test outcomes. Patients with a preoperative 10s-G&R test < 15 cycles have a 1.9 times higher risk of incomplete recovery of hand function (p = 0.005). Conclusion Most patients, regardless of their preoperative hand function, exhibit potential for improvement in hand dexterity. However, worse initial hand dexterity correlates with poorer outcomes. Surgical treatment is recommended before the 10s-G&R test drops below 15 cycles

Hybrid Alignment Training for Large Language Models

Alignment training is crucial for enabling large language models (LLMs) to cater to human intentions and preferences. It is typically performed based on two stages with different objectives: instruction-following alignment and human-preference alignment. However, aligning LLMs with these objectives in sequence suffers from an inherent problem: the objectives may conflict, and the LLMs cannot guarantee to simultaneously align with the instructions and human preferences well. To response to these, in this work, we propose a Hybrid Alignment Training (Hbat) approach, based on alternating alignment and modified elastic weight consolidation methods. The basic idea is to alternate between different objectives during alignment training, so that better collaboration can be achieved between the two alignment tasks.We experiment with Hbat on summarization and dialogue tasks. Experimental results show that the proposed \textsc{Hbat} can significantly outperform all baselines. Notably, Hbat yields consistent performance gains over the traditional two-stage alignment training when using both proximal policy optimization and direct preference optimization.accepted by ACL (Findings) 202

Scalable Nonlinear Sequence Generation using Composite Mersenne Product Registers

We introduce a novel composition method that combines linear feedback registers into larger nonlinear structures and generalizes earlier methods such as cascade connections. We prove a Chaining Period Theorem which provides the cycle structure of these register constructions. We then use this Chaining Period Theorem and a new construction we call a Product Register (PR) to introduce a flexible and scalable register family with desirable properties, which we term Composite Mersenne Product Registers (CMPRs). We provide an algorithm to estimate the linear complexity of a chosen CMPR and investigate the statistical properties and security of a CMPR-based pseudorandom generator. Finally, we propose a family of CMPR-based stream ciphers and provide comparisons with the TRIVIUM stream cipher in terms of hardware area and security. </p