FGF-10 Stimulates Limb Regeneration Ability in Xenopus laevis

AbstractBy reciprocal transplantation experiments with regenerative and nonregenerative Xenopus limbs, we recently demonstrated that the regenerative capacity of a Xenopus limb depends on mesenchymal tissue and we suggested that fgf-10 is likely to be involved in this capacity (Yokoyama et al., 2000, Dev. Biol. 219, 18–29). However, the data obtained in that study are not conclusive evidence that FGF-10 is responsible for the regenerative capacity. We therefore investigated the role of FGF-10 in regenerative capacity by directly introducing FGF-10 protein into nonregenerative Xenopus limb stumps. Exogenously applied FGF-10 successfully stimulated the regenerative capacity, resulting in the reinduction of all gene expressions (including shh, msx-1, and fgf-10) that we examined and the regeneration of well-patterned limb structures. We report here for the first time that a certain molecule activates the regenerative capacity of Xenopus limb, and this finding suggests that FGF-10 could be a key molecule in possible regeneration of nonregenerative limbs in higher vertebrates

Growing an engaging program of English elective courses

Since being enacted in response to continued falling student enrollment in elective English classes from 2004, and in preparation for the 2009 academic year, curriculum renewal and development of English elective courses offered to students across the faculties at Kyoto Women's University has, overall, resulted in greater numbers of students choosing to study in these courses. This paper discusses the continued focus on developing and delivering relevant and interesting courses for our students, as well as challenges that have been identified over the years with respect to both real and potential growth. Because the Junior College has closed, this paper will focus only on changes in university course enrollments in the wake of these curriculum renewal and development measures

ACCURACY EVALUATION OF STRUCTURE FROM MOTION THERMAL MOSAICING IN THE CENTER OF TOKYO

In the airborne and high-resolution measurement of Land Surface Temperature (LST) over large area, capturing and synthesizing of many images are necessary. In the conventional method, the process of georeferencing a large number of LST images is necessary to make one large image. Structure from Motion (SfM) technique was applied to automized the georeferencing process. We called it “SfM Thermal Mosaicing”. The objective of this study is to evaluate the accuracy of SfM thermal mosaicing in making an orthogonal LST image. By using airborne thermal images in the center of Tokyo, the LST image with the 2m resolution was created by using SfM thermal mosaicing. Its accuracy was then analyzed. The result showed that in the whole examined area, the mean error distance was 4.22m and in the small parts of the examined area, the mean the error distance was about 2m. Considering the image resolution, the error was minimal indicating good performance of the SfM thermal mosaicing. Another advantage of SfM thermal mosaicing is that it can make precise orthogonal LST image. With the progress of UAV and thermal cameras, the proposed method will be a powerful tool for the environmental researches on the LST

Multiple Digit Formation inXenopusLimb Bud Recombinants

AbstractWe prepared recombinant limb buds ofXenopustadpoles by grafting a mesenchyme mass of the hindlimb bud. TheXenopusrecombinant limb buds with dissociated and reaggregated mesenchyme developed more than 30 digits with cartilage segmentation, while those with undissociated mesenchyme developed a limb with normal cartilage pattern. Before the formation of multiple digits, a patchy expression pattern offgf-8,an AER marker, was observed in the distal region of recombinant limb buds.shh,a ZPA (zone of polarizing activity) marker, was expressed broadly in the distal region of recombinants. Recombinant limb buds with the reaggregated mesenchyme of anterior halves formed anterior digits with claws, and those with the mesenchyme of posterior halves formed posterior digits without claws. The temporal and spatial changes in the potency of multiple digit formation are discussed with reference to the regenerative capacity ofXenopuslimb buds

Factor Analysis of Damage to Small Earth Dams Due to the 1995 Hyogoken-Nambu Earthquake

Damage to small earth dams due to the Hyogoken-Namby Earthquake of January 17, 1995 is discussed. Investigations of 266 dams were conducted in the area where the JMA seismic intensity was 5 or higher, and which were located within about 50 kilometers from the earthquake source fault. Small earth dams suffered various forms of damage such as longitudinal cracking, transverse cracking, settlement and deformation of the dam body. The damage to small earth dams was classified into five grades from no damage to severe damage such as a complete failure. The damage grade was analyzed by several factors such as distance from the fault, topography and geology, intensity of quake motion, direction of dam axis against the fault, year of completion, and height of dam. The characteristics of factors affecting damage to small earth dams were evaluated

腎糸球体病変における組織適合抗原class II抗原表出の臨床病理学的意義

金沢大学医学部研究課題/領域番号:63770406, 研究期間(年度):1988出典：研究課題「腎糸球体病変における組織適合抗原class II抗原表出の臨床病理学的意義」課題番号63770406（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） （https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-63770406/）を加工して作

腎糸球体病変における組織適合抗原ならびに各種増殖因子の発現意義

金沢大学医学部研究課題/領域番号:01770407, 研究期間(年度):1989出典：研究課題「腎糸球体病変における組織適合抗原ならびに各種増殖因子の発現意義」課題番号01770407（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） （https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-01770407/）を加工して作