234 research outputs found
Re-criticism of Geomantic Omen in Modern Design from the Perspective of Data Analysis
Geomantic omen is both strange and familiar to the contemporary people. It is not only a part of the traditional Chinese culture, but also contains the contradictions and disputes in Chinese long history of thought, practice and theory. This article is based on the context of modern design, discuss the reason of the Geomantic omen cannot be the key factors of modern design from three perspectives, including research trend, discipline development, practice creation. Through the summary of data, typical cases, and geomantic theory, it is believed that modern geomantic research should be based on rational evaluation and theoretical research. Except that, geomancy can be study not only by using modern science and technology, but also through transcending the ideological level. Finally, the idea of the future development of geomantic is set up for the re-thinking and re-exploration of the contemporary research
3D-STMN: Dependency-Driven Superpoint-Text Matching Network for End-to-End 3D Referring Expression Segmentation
In 3D Referring Expression Segmentation (3D-RES), the earlier approach adopts
a two-stage paradigm, extracting segmentation proposals and then matching them
with referring expressions. However, this conventional paradigm encounters
significant challenges, most notably in terms of the generation of lackluster
initial proposals and a pronounced deceleration in inference speed. Recognizing
these limitations, we introduce an innovative end-to-end Superpoint-Text
Matching Network (3D-STMN) that is enriched by dependency-driven insights. One
of the keystones of our model is the Superpoint-Text Matching (STM) mechanism.
Unlike traditional methods that navigate through instance proposals, STM
directly correlates linguistic indications with their respective superpoints,
clusters of semantically related points. This architectural decision empowers
our model to efficiently harness cross-modal semantic relationships, primarily
leveraging densely annotated superpoint-text pairs, as opposed to the more
sparse instance-text pairs. In pursuit of enhancing the role of text in guiding
the segmentation process, we further incorporate the Dependency-Driven
Interaction (DDI) module to deepen the network's semantic comprehension of
referring expressions. Using the dependency trees as a beacon, this module
discerns the intricate relationships between primary terms and their associated
descriptors in expressions, thereby elevating both the localization and
segmentation capacities of our model. Comprehensive experiments on the
ScanRefer benchmark reveal that our model not only set new performance
standards, registering an mIoU gain of 11.7 points but also achieve a
staggering enhancement in inference speed, surpassing traditional methods by
95.7 times. The code and models are available at
https://github.com/sosppxo/3D-STMN
Tile Classification Based Viewport Prediction with Multi-modal Fusion Transformer
Viewport prediction is a crucial aspect of tile-based 360 video streaming
system. However, existing trajectory based methods lack of robustness, also
oversimplify the process of information construction and fusion between
different modality inputs, leading to the error accumulation problem. In this
paper, we propose a tile classification based viewport prediction method with
Multi-modal Fusion Transformer, namely MFTR. Specifically, MFTR utilizes
transformer-based networks to extract the long-range dependencies within each
modality, then mine intra- and inter-modality relations to capture the combined
impact of user historical inputs and video contents on future viewport
selection. In addition, MFTR categorizes future tiles into two categories: user
interested or not, and selects future viewport as the region that contains most
user interested tiles. Comparing with predicting head trajectories, choosing
future viewport based on tile's binary classification results exhibits better
robustness and interpretability. To evaluate our proposed MFTR, we conduct
extensive experiments on two widely used PVS-HM and Xu-Gaze dataset. MFTR shows
superior performance over state-of-the-art methods in terms of average
prediction accuracy and overlap ratio, also presents competitive computation
efficiency.Comment: This paper is accepted by ACM-MM 202
Oral Probiotics Ameliorate the Behavioral Deficits Induced by Chronic Mild Stress in Mice via the Gut Microbiota-Inflammation Axis
In recent years, a burgeoning body of research has revealed links between depression and the gut microbiota, leading to the therapeutic use of probiotics for stress-related disorders. In this study, we explored the potential antidepressant efficacy of a multi-strain probiotics treatment (Lactobacillus helveticus R0052, Lactobacillus plantarum R1012, and Bifidobacterium longum R0175) in a chronic mild stress (CMS) mouse model of depression and determined its probable mechanism of action. Our findings revealed that mice subjected to CMS exhibited anxiety- and depressive-like behaviors in the sucrose preference test, elevated plus maze, and forced swim test, along with increased interferon-γ, tumor necrosis factor-α, and indoleamine 2,3-dioxygenase-1 levels in the hippocampus. Moreover, the microbiota distinctly changed from the non-stress group and was characterized by highly diverse bacterial communities associated with significant reductions in Lactobacillus species. Probiotics attenuated CMS-induced anxiety- and depressive-like behaviors, significantly increased Lactobacillus abundance, and reversed the CMS-induced immune changes in the hippocampus. Thus, the possible mechanism involved in the antidepressant-like activity of probiotics is correlated with Lactobacillus species via the gut microbiota-inflammation-brain axis
Evaluating the Potential of Leading Large Language Models in Reasoning Biology Questions
Recent advances in Large Language Models (LLMs) have presented new
opportunities for integrating Artificial General Intelligence (AGI) into
biological research and education. This study evaluated the capabilities of
leading LLMs, including GPT-4, GPT-3.5, PaLM2, Claude2, and SenseNova, in
answering conceptual biology questions. The models were tested on a
108-question multiple-choice exam covering biology topics in molecular biology,
biological techniques, metabolic engineering, and synthetic biology. Among the
models, GPT-4 achieved the highest average score of 90 and demonstrated the
greatest consistency across trials with different prompts. The results
indicated GPT-4's proficiency in logical reasoning and its potential to aid
biology research through capabilities like data analysis, hypothesis
generation, and knowledge integration. However, further development and
validation are still required before the promise of LLMs in accelerating
biological discovery can be realized
"To Chat-GPT or not to Chat-GPT":Navigating the paradoxes of generative AI in the advertising industry
Generative AI technology is evoking both excitement and fear about its potential impact across a host of industries—including advertising, where it is expected to have a significant disruptive effect. This article utilizes the paradox lens to explore the implications of text-to-text generative AI in the form of ChatGPT for the advertising industry. Drawing on 48 interviews with advertising professionals, we identify three operational paradoxes that are associated with conducting research, creativity, efficiency, and one psychological paradox related to work identity. To gain a competitive advantage, we urge practitioners to adopt a confrontation-based coping strategy to navigate these paradoxes. This can be mobilized via an ambidexterity or contingency paradox management approach. We outline specific tactics in this article.</p
Monitoring the Severity of Pantana phyllostachysae Chao Infestation in Moso Bamboo Forests Based on UAV Multi-Spectral Remote Sensing Feature Selection
In recent years, the rapid development of unmanned aerial vehicle (UAV) remote sensing technology has provided a new means to efficiently monitor forest resources and effectively prevent and control pests and diseases. This study aims to develop a detection model to study the damage caused to Moso bamboo forests by Pantana phyllostachysae Chao (PPC), a major leaf-eating pest, at 5 cm resolution. Damage sensitive features were extracted from multispectral images acquired by UAVs and used to train detection models based on support vector machines (SVM), random forests (RF), and extreme gradient boosting tree (XGBoost) machine learning algorithms. The overall detection accuracy (OA) and Kappa coefficient of SVM, RF, and XGBoost were 81.95%, 0.733, 85.71%, 0.805, and 86.47%, 0.811, respectively. Meanwhile, the detection accuracies of SVM, RF, and XGBoost were 78.26%, 76.19%, and 80.95% for healthy, 75.00%, 83.87%, and 79.17% for mild damage, 83.33%, 86.49%, and 85.00% for moderate damage, and 82.5%, 90.91%, and 93.75% for severe damage Moso bamboo, respectively. Overall, XGBoost exhibited the best detection performance, followed by RF and SVM. Thus, the study findings provide a technical reference for the regional monitoring and control of PPC in Moso bamboo
Function of TRP channels in monocytes/macrophages
The transient receptor potential channel (TRP channel) family is a kind of non- specific cation channel widely distributed in various tissues and organs of the human body, including the respiratory system, cardiovascular system, immune system, etc. It has been reported that various TRP channels are expressed in mammalian macrophages. TRP channels may be involved in various signaling pathways in the development of various systemic diseases through changes in intracellular concentrations of cations such as calcium and magnesium. These TRP channels may also intermingle with macrophage activation signals to jointly regulate the occurrence and development of diseases. Here, we summarize recent findings on the expression and function of TRP channels in macrophages and discuss their role as modulators of macrophage activation and function. As research on TRP channels in health and disease progresses, it is anticipated that positive or negative modulators of TRP channels for treating specific diseases may be promising therapeutic options for the prevention and/or treatment of disease
NCAPG2 could be an immunological and prognostic biomarker: From pan-cancer analysis to pancreatic cancer validation
More recently, NCAPG2 has emerged as an intrinsically essential participant of the condensin II complex involved in the process of chromosome cohesion and stabilization in mitosis, and its position in particular tumours is now being highlighted. Simultaneously, the genetic properties of NCAPG2 hint that it might have enormous potential to interpret the malignant progression of tumors in a broader perspective, that is, in pan-cancer. Yet, at present, this recognition remains merely superficial and there is a lack of more detailed studies to explore the underlying pathogenesis. To meet this need, the current study was undertaken to comprehensively elucidate the potential functions of NCAPG2 in pan-cancer, based on a combination of existing databases like TCGA and GTEx. NCAPG2 was identified to be overexpressed in almost every tumor and to exhibit significant prognostic and diagnostic efficacy. Furthermore, the correlation between NCAPG2 and selected immune features, namely immune cell infiltration, immune checkpoint genes, TMB, MSI, etc. also indicates that NCAPG2 could potentially be applied in guidance of immunotherapy. Subsequently, in pancreatic cancer, this study further clarified the utility of NCAPG2 that downregulation of its expression could result in reduced proliferation, invasion and metastasis of pancreatic cancer cells, among such phenotypical changes, the epithelial-mesenchymal transition disruption could be at least one of the possible mechanisms raising or enhancing tumorigenesis. Taken above, NCAPG2, as a member of pan-oncogenes, would serve as a biomarker and potential therapeutic target for a range of malignancies, sharing new insights into precision medicine
- …