Application of Graphene Nanocomposite in Motion Sensing of Human Body

For exploring the application of graphene nano-composite, graphene is combined with other nano-materials to develop a new graphene nano-composite with high conductivity, good biocompatibility and strong affinity for enzymes, which improved the working performance of sensors in human motion sensing. Graphene oxide (GO) is prepared by using Hummers and offeman methods, and graphene is prepared from graphene oxide with glucose as a reducing agent. On the basis of electro-deposition of Prussian blue chitosan (PB-CS) film modified gold electrode, a new nano material graphene is introduced, and glucose oxidase as a model enzyme, a glucose biosensor based on RGO/PB-CS nano-composite is constructed. The research results showed that the sensor constructed has higher sensitivity, lower detection limit and smaller apparent Michaelis constant. To sum up, the combination of graphene and Prussian blue chitosan effectively promoted the electron transfer between the electrode surface and the analytical substrate, and improved the working performance of the sensor, which has potential application value in human motion sensing

A new error bound for linear complementarity problems involving B− B- matrices

In this paper, a new error bound for the linear complementarity problems of $B-$matrices which is a subclass of the $P-$matrices is presented. Theoretical analysis and numerical example illustrate that the new error bound improves some existing results

Contrastive analysis of distractions to pilot caused by various flight instrument displays

Automation of aircraft instrument displays enhances flight safety, but it also increases complexity and pilot workload. Executing changes in flight plan, navigation or communication during flight using flight instrument switches often increases pilots’ workload and this may also cause distraction that adds potential risks to flight safety. This study compares the conventional avionics panel and touchscreen avionic panel to find out the least distractive panel for the pilots. Thirty simulated flights using four different pilots were carried out; and aircraft speed, altitude and heading parameters using both avionics systems were observed to study the operational efficiency and pilot distraction resulted from each of the avionic systems. The distraction was examined by a parameter analysis based on the Mean Squared Error (MSE) mathematical model and visually by recording videos of each simulated flight. The results indicate that the touchscreen system is more efficient and less erroneous for the aircraft in maintaining the parameters as compared with the conventional system. There is also a clear relationship between task completion time and disruption level on the parameters control

Denervation as a Common Mechanism Underlying Different Pulmonary Vein Isolation Strategies for Paroxysmal Atrial Fibrillation: Evidenced by Heart Rate Variability after Ablation

Backgrounds. Segmental and circumferential pulmonary vein isolations (SPVI and CPVI) have been demonstrated to be effective therapies for paroxysmal atrial fibrillation (PAF). PVI is well established as the endpoint of different ablation techniques, whereas it may not completely account for the long-term success. Methods. 181 drug-refractory symptomatic PAF patients were referred for segmental or circumferential PVI (SPVI = 67; CPVI = 114). Heart rate variability (HRV) was assessed before and after the final ablation. Results. After following up for 62.23±12.75 months, patients underwent 1.41±0.68 procedures in average, and the success rates in SPVI and CPVI groups were comparable. 119 patients were free from AF recurrence (SPVI-S, n=43; CPVI-S, n=76). 56 patients had recurrent episodes (SPVI-R, n=21; CPVI-R, n=35). Either ablation technique decreased HRV significantly. Postablation SDNN and rMSSD were significantly lower in SPVI-S and CPVI-S subgroups than in SPVI-R and CPVI-R subgroups (SPVI-S versus SPVI-R: SDNN 91.8±32.6 versus 111.5±36.2 ms, rMSSD 47.4±32.3 versus 55.2±35.2 ms; CPVI-S versus CPVI-R: SDNN 83.0±35.6 versus 101.0±40.7 ms, rMSSD 41.1±22.9 versus 59.2±44.8 ms; all P<0.05). Attenuation of SDNN and rMSSD remained for 12 months in SPVI-S and CPVI-S subgroups, whereas it recovered earlier in SPVI-R and CPVI-R subgroups. Multivariate logistic regression analysis identified SDNN as the only predictor of long-term success. Conclusions. Beyond PVI, denervation may be a common mechanism underlying different ablation strategies for PAF

The feasibility and safety of his-purkinje conduction system pacing in patients with heart failure with severely reduced ejection fraction

ObjectiveThe purpose of this study was to evaluate the feasibility and outcomes of conduction system pacing (CSP) in patients with heart failure (HF) who had a severely reduced left ventricular ejection fraction (LVEF) of less than 30% (HFsrEF).MethodsBetween January 2018 and December 2020, all consecutive HF patients with LVEF &lt; 30% who underwent CSP at our center were evaluated. Clinical outcomes and echocardiographic data [LVEF and left ventricular end-systolic volume (LVESV)], and complications were all recorded. In addition, clinical and echocardiographic (≥5% improvement in LVEF or ≥15% decrease in LVESV) responses were assessed. The patients were classified into a complete left bundle branch block (CLBBB) morphology group and a non-CLBBB morphology group according to the baseline QRS configuration.ResultsSeventy patients (66 ± 8.84 years; 55.7% male) with a mean LVEF of 23.2 ± 3.23%, LVEDd of 67.33 ± 7.47 mm and LVESV of 212.08 ± 39.74 ml were included. QRS configuration at baseline was CLBBB in 67.1% (47/70) of patients and non-CLBBB in 32.9%. At implantation, the CSP threshold was 0.6 ± 0.3 V @ 0.4 ms and remained stable during a mean follow-up of 23.43 ± 11.44 months. CSP resulted in significant LVEF improvement from 23.2 ± 3.23% to 34.93 ± 10.34% (P &lt; 0.001) and significant QRS narrowing from 154.99 ± 34.42 to 130.81 ± 25.18 ms (P &lt; 0.001). Clinical and echocardiographic responses were observed in 91.4% (64/70) and 77.1% (54/70) of patients. Super-response to CSP (≥15% improvement in LVEF or ≥30% decrease in LVESV) was observed in 52.9% (37/70) of patients. One patient died due to acute HF and following severe metabolic disorders. Baseline BNP (odds ratio: 0.969; 95% confidence interval: 0.939–0.989; P = 0.045) was associated with echocardiographic response. The proportions of clinical and echocardiographic responses in the CLBBB group were higher than those in the non-CLBBB group but without significant statistical differences.ConclusionsCSP is feasible and safe in patients with HFsrEF. CSP is associated with a significant improvement in clinical and echocardiographic outcomes, even for patients with non-CLBBB widened QRS