71 research outputs found
The Path of Least Resistance: How Strict Chinese Stock Market Regulation Incentivizes Chinese Companies to List in Foreign Stock Exchanges
Despite the recent trade dispute, decades of increased trade between the U.S. and China have given Chinese companies more opportunities to list on foreign stock markets, so they can find better financing opportunities in foreign markets. With the rapid development of the Chinese financial industry and the continuous spread of news on various company listings, why is it that many Chinese companies choose to list overseas, especially in the U.S. and Hong Kong, but not in China? In addition, what is the difference between the U.S. and Hong Kong exchanges, and how does that difference affect Chinese companiesâ choice of listing location? I propose that this is largely because the Chinese government has imposed relatively strict constraints on its stock exchanges, such as strict requirements for the profit ability of listing firms, and requirements that the company have a good background with the government. Thus, it makes a lot of Chinese companies choose to list on foreign exchanges. The weaker restrictions of the U.S. and Hong Kong stock exchanges greatly influence the decisions of Chinese companies to list abroad.
The Hong Kong exchanges provides firms with investors who have an understanding of Chinese companies and easy listing requirements relative to mainland China, while the U.S. exchanges offer a more open market system, which means more investors, faster listing speed and fewer restrictions than in Hong Kong to attract a large number of Chinese companies to go public successfully
A Review of Research on the Potential Value and Realistic Dilemma for Homework in Physical Education
Homework in physical education (PE) has become a central strategy of educational reform movements (Novak & Lynott, 2015). A Chinese policy called âthe Double Reductionâ provides an opportunity for the implementation of PE homework. There are abundant studies about homework in subjects like English, Math, Science, etc., but relatively few studies have been devoted specifically to PE homework. The primary purpose of this study was to analyze the value and dilemma of PE homework, with the goal of identifying the major contributions to the research knowledge base. We followed three parts to conduct the review: a) literature was searched using the following keywords: âPE homeworkâ, OR âactive homeworkâ, AND âthe value and dilemmaâ, AND/OR âhomework in physical educationâ or âactivity-based homeworkâ; b) A document analysis was conducted regarding the Chinese policy related to homework in PE, including homeworkâs guidelines, composition system, and cultivation path, etc.; c) A total of 34 highly relevant articles were selected. The main value and dilemma of PE homework were summarized as follows: a) The PE homework appears to be an effective way of promoting policy implementation and renewal, providing a well-rounded approach to help students achieve educational goal, improving youth physical & mental health, and increasing communications with family members. b) The current PE homework has failed to realize the foregoing values due to some difficulties, including the lack of family exercise atmosphere, the absence of community organizations, and the huge amount of negative news in social media. c) Only three studies provided coping strategies to deal with the dilemma from a Social System Theory perspective, such as strengthening institutional construction, building a multivariate framework, shaping the paradigm, integrating online platform, and developing an assessment system. Most studies focused on the micro level about âthe value and dilemma of homework implementationâ without consideration of the other key factors from macro level. Based on the literature reviewed, a comprehensive theoretical model for PE homework is proposed to provide guidance for future research endeavors and facilitate implementation of the guidelines
Neutrophil heterogeneity and aging: implications for COVID-19 and wound healing
Neutrophils play a critical role in the immune response to infection and tissue injury. However, recent studies have shown that neutrophils are a heterogeneous population with distinct subtypes that differ in their functional properties. Moreover, aging can alter neutrophil function and exacerbate immune dysregulation. In this review, we discuss the concept of neutrophil heterogeneity and how it may be affected by aging. We then examine the implications of neutrophil heterogeneity and aging for COVID-19 pathogenesis and wound healing. Specifically, we summarize the evidence for neutrophil involvement in COVID-19 and the potential mechanisms underlying neutrophil recruitment and activation in this disease. We also review the literature on the role of neutrophils in the wound healing process and how aging and neutrophil heterogeneity may impact wound healing outcomes. Finally, we discuss the potential for neutrophil-targeted therapies to improve clinical outcomes in COVID-19 and wound healing
Ursinus College Student-Managed Investment Fund Prospectus, Fall 2018
This prospectus contains a performance summary for previous stocks and endowment funds as well as strategy and analysis for the following new stocks in the managed fund: American Woodmark Corporation, Comtech Telecommunications Corp. and LGL Group, Inc
Molecular basis of ligand recognition and activation of human V2 vasopressin receptor.
Vasopressin type 2 receptor (V2R) belongs to the vasopressin (VP)/oxytocin (OT) receptor subfamily of G protein-coupled receptors (GPCRs), which comprises at least four closely related receptor subtypes: V1aR, V1bR, V2R, and OTR. These receptors are activated by arginine vasopressin (AVP) and OT, two endogenous nine-amino acid neurohypophysial hormones, which are thought to mediate a biologically conserved role in social behavior and sexual reproduction. V2R is mainly expressed in the renal collecting duct principal cells and mediates the antidiuretic action of AVP by accelerating water reabsorption, thereby playing a vital role in controlling water homeostasis. Moreover, numerous gain-of-function and loss-of-function mutations of V2R have been identified and are closely associated with human diseases, including nephrogenic syndrome of inappropriate diuresis (NSIAD) and X-linked congenital nephrogenic diabetes insipidus (NDI). Thus, V2R has attracted intense interest as a drug target. However, due to a lack of structural information, how AVP recognizes and activates V2R remains elusive, which hampers the V2R-targeted drug design. Here, we determined a 2.6 Ă
resolution cryo-EM structure of the full-length, G s -coupled human V2R bound to AVP (Fig. 1a; Supplementary information, Table S1). The G s protein was engineered based on mini-G s that was used in the crystal structure determination of the G s -coupled adenosine A 2A receptor (A 2A R) to stabilize the V2RâG s protein complex (Supplementary information, Data S1). The final structure of the AVPâV2RâG s complex contains all residues of AVP (residues 1â9), the GÎą s Ras-like domain, Gβγ subunits, Nb35, scFv16, and the V2R residues from T31 to L339 8.57 (superscripts refer to BallesterosâWeinstein numbering). The majority of amino acid side chains, including AVP, transmembrane domain (TMD), all flexible intracellular loops (ICLs) and extracellular loops (ECLs) except for ICL3 and G185âG188 in ECL2, were well resolved in the model, refined against the EM density map (Fig. 1a; Supplementary information, Figs. S1â3). The complex structure can provide detailed information on the binding interface between AVP and helix bundle of the receptor, as well as the receptorâG s interface
The Grizzly, March 3, 2016
UC Reveals Plans for Semester in Philly, New Coffee Shop ⢠Professor Romano Elected to National Book Critics Circle ⢠Business Students Win Competition in Philadelphia ⢠Relay for Life Gets Ready ⢠International Perspective: Cultural Differences in Driving Practices ⢠Falling in Love with Ursinus\u27 Unique History ⢠Ping Pong Club Bounces Back ⢠Using the Present to Prepare for the Future ⢠Opinions: New Barbie Figures are Anti-Progressive; UC Second-Ever Musical Wows Audience ⢠Freshman Phenom ⢠Baseball Ready to Slug Awayhttps://digitalcommons.ursinus.edu/grizzlynews/1685/thumbnail.jp
Multimodal transformer augmented fusion for speech emotion recognition
Speech emotion recognition is challenging due to the subjectivity and ambiguity of emotion. In recent years, multimodal methods for speech emotion recognition have achieved promising results. However, due to the heterogeneity of data from different modalities, effectively integrating different modal information remains a difficulty and breakthrough point of the research. Moreover, in view of the limitations of feature-level fusion and decision-level fusion methods, capturing fine-grained modal interactions has often been neglected in previous studies. We propose a method named multimodal transformer augmented fusion that uses a hybrid fusion strategy, combing feature-level fusion and model-level fusion methods, to perform fine-grained information interaction within and between modalities. A Model-fusion module composed of three Cross-Transformer Encoders is proposed to generate multimodal emotional representation for modal guidance and information fusion. Specifically, the multimodal features obtained by feature-level fusion and text features are used to enhance speech features. Our proposed method outperforms existing state-of-the-art approaches on the IEMOCAP and MELD dataset
The Relationship Between Big Five Personality Traits and Psychotic Experience in a Large Non-clinical Youth Sample: The Mediating Role of Emotion Regulation
Objective: Despite a long history of interest in personality traits and psychosis, the association between personality traits and psychotic experiences in the general population is not yet well understood. One possible factor that could influence the degree of distress from psychotic experiences is emotion regulation. The purpose of this study was to explore whether the association between personality and psychotic symptoms is already apparent in non-clinical youth as well as the mediating role of emotion regulation strategies between personality traits and psychotic experiences.Methods: Three thousand one hundred and forty seven college students were surveyed via self-report questionnaires measuring the Five-Factor model of personality, emotion regulation strategies, and psychotic experiences.Results: Neuroticism was found to be significantly positively correlated with psychotic experiences, while Extraversion, Openness, Agreeableness, and Conscientiousness were found to be significantly negatively correlated. Both the suppression and reappraisal strategies mediated the relationship between personality traits and psychotic experiences.Conclusion: Our findings suggest that youth with certain personality traits are more likely to have psychotic experiences. The reappraisal emotion regulation strategy could serve as a protective factor against the distress of psychotic experiences
Assisted reproductive technology and interactions between serum basal FSH/LH and ovarian sensitivity index
ObjectivesThis study aimed to investigate whether the FSH (follicle-stimulating hormone)/LH (Luteinizing hormone) ratio correlates with ovarian response in a cross-sectional retrospective study of a population with normal levels of anti-MĂźllerian hormone (AMH).MethodsThis was a retrospective crossâsectional study with data obtained from medical records from March 2019 to December 2019 at the reproductive center in the Affiliated Hospital of Southwest Medical University. The Spearmans correlation test evaluated correlations between Ovarian sensitivity index (OSI) and other parameters. The relationship between basal FSH/LH and ovarian response was analyzed using smoothed curve fitting to find the threshold or saturation point for the population with mean AMH level (1.1<AMH<6Îźg/L). The enrolled cases were divided into two groups according to AMH threshold. Cycle characteristics, cycle information and cycle outcomes were compared. The Mann-Whitney U test was used to compare different parameters between two groups separated by basal FSH/LH in the AMH normal group. Univariate logistic regression analysis and multivariate logistic regression analysis were performed to find the risk factor for OSI.ResultsA total of 428 patients were included in the study. A significant negative correlation was observed between OSI and age, FSH, basal FSH/LH, Gn total dose, and Gn total days, while a positive correlation was found with AMH, AFC, retrieved oocytes, and MII egg. In patients with AMH <1.1 ug/L, OSI values decreased as basal FSH/LH levels increased, while in patients with 1.1<AMH<6 ug/L, OSI values remained stable with increasing basal FSH/LH levels. Logistic regression analysis identified age, AMH, AFC, and basal FSH/LH as significant independent risk factors for OSI.ConclusionsWe conclude that increased basal FSH/LH in the AMH normal group reduces the ovarian response to exogenous Gn. Meanwhile, basal FSH/LH of 3.5 was found to be a useful diagnostic threshold for assessing ovarian response in people with normal AMH levels. OSI can be used as an indicator of ovarian response in ART treatment
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