4,705 research outputs found
Machine learning for fiber nonlinearity mitigation in long-haul coherent optical transmission systems
Fiber nonlinearities from Kerr effect are considered as major constraints for enhancing the transmission capacity in current optical transmission systems. Digital nonlinearity compensation techniques such as digital backpropagation can perform well but require high computing resources. Machine learning can provide a low complexity capability especially for high-dimensional classification problems. Recently several supervised and unsupervised machine learning techniques have been investigated in the field of fiber nonlinearity mitigation. This paper offers a brief review of the principles, performance and complexity of these machine learning approaches in the application of nonlinearity mitigation
Development of microcantilever sensors for cell studies
Micro- and nano- electromechanical devices such as microcantilevers have paved the
way for a large variety of new possibilities, such as the rapid diagnosis of diseases and a
high throughput platform for drug discovery. Conventional cell assay methods rely on
the addition of reagents, disrupting the measurement, therefore providing only the
endpoint data of the cell growth experiment. In addition, these methods are typically
slow to provide results and time and cost consuming. Therefore, microcantilever sensors
are a great platform to conduct cell culturing experiments for cell culture, viability,
proliferation, and cytotoxicity monitoring, providing advantages such as being able to
monitor cell kinetics in real time without requiring external reagents, in addition to
being low cost and fast, which conventional cell assay methods are unable to provide.
This work aims to develop and test different types of microcantilever biosensors for the
detection and monitoring of cell proliferation. This approach will overcome many of the
current challenges facing microcantilever biosensors, including but not limited to
achieving characteristics such as being low cost, rapid, easy to use, highly sensitive,
label-free, multiplexed arrays, etc.
Microcantilever sensor platforms utilizing both a single and scanning optical beam
detection methods were developed and incorporated aspects such as temperature control,
calibration, and readout schemes. Arrays of up to 16 or 32 microcantilever sensors can
be simultaneously measured with integrated microfluidic channels. The effectiveness of
these cantilever platforms are demonstrated through multiple studies, including
examples of growth induced bending of polyimide cantilevers for simple real-time yeast
cell measurements and a microcantilever array for rapid, sensitive, and real-time
measurement of nanomaterial toxicity on the C3A human liver cell line. In addition,
other techniques for microcantilever arrays and microfluidics will be presented along
with demonstrations for the ability for stem cell growth monitoring and pathogen
detection
High-Performance Reverse Osmosis Membrane Enabled by Nanofillers and Surface Modification
With the rising demand for sustainably producing fresh water from saline sources, many researchers have been attracted to develop new reverse osmosis (RO) membranes with high water flux and salt rejection. Despite the great achievements researchers have made, there is still significant room for improving the water permeability and salt rejection of an RO membrane. Herein, we fabricated a RO membrane of advanced 3-layer structure and better performance both in anti-fouling and in water flux. This advanced membrane contains three layers with different modifications. The first modification was done by embedding zeolite and graphene oxide (GO) in the selective polyamide (PA) layer to introduce water flux channel. The second modification was an additional GO layer on the PA surface working as an anti-fouling layer. For final modification, we added a polyethylene glycol (PEG) layer which could serve to repel the organic foulant. The water permeability, salt rejection property, and anti-fouling ability of this new membrane have been investigated. We concluded that the combination of these structures led to an overall excellent RO performance which was supported by our experimental results
High-Performance Reverse Osmosis Membrane Enabled by Nanofillers and Surface Modification
With the rising demand for sustainably producing fresh water from saline sources, many researchers have been attracted to develop new reverse osmosis (RO) membranes with high water flux and salt rejection. Despite the great achievements researchers have made, there is still significant room for improving the water permeability and salt rejection of an RO membrane. Herein, we fabricated a RO membrane of advanced 3-layer structure and better performance both in anti-fouling and in water flux. This advanced membrane contains three layers with different modifications. The first modification was done by embedding zeolite and graphene oxide (GO) in the selective polyamide (PA) layer to introduce water flux channel. The second modification was an additional GO layer on the PA surface working as an anti-fouling layer. For final modification, we added a polyethylene glycol (PEG) layer which could serve to repel the organic foulant. The water permeability, salt rejection property, and anti-fouling ability of this new membrane have been investigated. We concluded that the combination of these structures led to an overall excellent RO performance which was supported by our experimental results
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