Nevus-Like Appearance of Primary Malignant Melanoma of the Esophagus

The primary malignant melanoma of the esophagus (PMME) is a rare malignant disease, accounting for only 0.1–0.2% of all esophageal neoplasms, and the majority of the patients are diagnosed at advanced stages with poor prognosis. We present here a case of 56-year-old woman with epigastric pain and her endoscopic finding revealed several flat and black pigmented mucosal lesions within the distal portion of the esophagus which looked like flat nevus. The histopathology and immunohistochemical profile of the tissue specimens were diagnostic of malignant melanoma

ORIGIN OF MELTING ANOMALIES IN THE JAPAN-BAIKAL CORRIDOR OF ASIA AT THE LATEST GEODYNAMIC STAGE: EVOLUTION FROM THE MANTLE TRANSITION LAYER AND GENERATION BY LITHOSPHERIC TRANSTENSION

At the latest geodynamic stage that is characterized by forces and processes of the last 90 Ma the lithosphere of Asia has been reactivated due to four main force factors: 1) mantle melting anomalies, 2) subduction-related interaction between the Pacific plates and the continental eastern margin, 3) convergent interaction between India and the continental southern margin, and 4) quasiperiodic orbital variations of the Earth. The starting point of the latest geodynamic stage [Rasskazov, Chuvashova, 2013] is consistent with the change of the Earth’s rotation due to the resonant interaction of its orbit with the orbit of the Mars in the time interval of 87–85 Ma [Ma et al., 2017].At the latest geodynamic stage that is characterized by forces and processes of the last 90 Ma the lithosphere of Asia has been reactivated due to four main force factors: 1) mantle melting anomalies, 2) subduction-related interaction between the Pacific plates and the continental eastern margin, 3) convergent interaction between India and the continental southern margin, and 4) quasiperiodic orbital variations of the Earth. The starting point of the latest geodynamic stage [Rasskazov, Chuvashova, 2013] is consistent with the change of the Earth’s rotation due to the resonant interaction of its orbit with the orbit of the Mars in the time interval of 87–85 Ma [Ma et al., 2017]