Interplay between single-stranded binding proteins on RNA secondary structure

RNA protein interactions control the fate of cellular RNAs and play an important role in gene regulation. An interdependency between such interactions allows for the implementation of logic functions in gene regulation. We investigate the interplay between RNA binding partners in the context of the statistical physics of RNA secondary structure, and define a linear correlation function between the two partners as a measurement of the interdependency of their binding events. We demonstrate the emergence of a long-range power-law behavior of this linear correlation function. This suggests RNA secondary structure driven interdependency between binding sites as a general mechanism for combinatorial post-transcriptional gene regulation.Comment: 26 pages, 17 figure

Monotonicity-based inversion of the fractional Schr\"odinger equation I. Positive potentials

We consider the inverse problems of for the fractional Schr\"odinger equation by using monotonicity formulas. We provide if-and-only-if monotonicity relations between positive bounded potentials and their associated nonlocal Dirichlet-to-Neumann maps. Based on the monotonicity relation, we can prove uniqueness for the nonlocal Calder\'on problem in a constructive manner. Secondly, we offer a reconstruction method for an unknown obstacles in a given domain. Our method is independent of the dimension $n\geq 2$ and only requires the background solution of the fractional Schr\"odinger equation

Boundary determination of the Lam\'e moduli for the isotropic elasticity system

We consider the inverse boundary value problem of determining the Lam\'e moduli of an isotropic, static elasticity equations of system at the boundary from the localized Dirichlet-to-Neumann map. Assuming appropriate local regularity assumptions as weak as possible on the Lam\'e moduli and on the boundary, we give explicit pointwise reconstruction formulae of the Lam\'e moduli and their higher order derivatives at the boundary from the localized Dirichlet-to-Neumann map.Comment: 24 page