6,543 research outputs found
Investigation and characterization of constraint effects on flaw growth during fatigue loading of composite materials
An investigative program is presented in an attempt to add to the current understanding of constraint effects on the response of composite materials under cyclic loading. The objectives were: (1) to use existing data and to develop additional data in order to establish an understanding and quantitative description of flaw growth in unidirectional lamina under cyclic loading at different load direction to fiber direction angles; (2) to establish a similar understanding and description of flaw growth in lamina which are embedded in laminates between other unflawed lamina; (3) to determine the nature of the influence of constraint on flaw growth by quantitatively comparing the results of the tests; and (4) to develop a model and philosophy of constraints effects based on our investigative results
Coarsening Dynamics of a One-Dimensional Driven Cahn-Hilliard System
We study the one-dimensional Cahn-Hilliard equation with an additional
driving term representing, say, the effect of gravity. We find that the driving
field has an asymmetric effect on the solution for a single stationary
domain wall (or `kink'), the direction of the field determining whether the
analytic solutions found by Leung [J.Stat.Phys.{\bf 61}, 345 (1990)] are
unique. The dynamics of a kink-antikink pair (`bubble') is then studied. The
behaviour of a bubble is dependent on the relative sizes of a characteristic
length scale , where is the driving field, and the separation, ,
of the interfaces. For the velocities of the interfaces are
negligible, while in the opposite limit a travelling-wave solution is found
with a velocity . For this latter case () a set of
reduced equations, describing the evolution of the domain lengths, is obtained
for a system with a large number of interfaces, and implies a characteristic
length scale growing as . Numerical results for the domain-size
distribution and structure factor confirm this behavior, and show that the
system exhibits dynamical scaling from very early times.Comment: 20 pages, revtex, 10 figures, submitted to Phys. Rev.
Derivative moments in turbulent shear flows
We propose a generalized perspective on the behavior of high-order derivative
moments in turbulent shear flows by taking account of the roles of small-scale
intermittency and mean shear, in addition to the Reynolds number. Two
asymptotic regimes are discussed with respect to shear effects. By these means,
some existing disagreements on the Reynolds number dependence of derivative
moments can be explained. That odd-order moments of transverse velocity
derivatives tend not vanish as expected from elementary scaling considerations
does not necessarily imply that small-scale anisotropy persists at all Reynolds
numbers.Comment: 11 pages, 7 Postscript figure
Optimal Location of Sources in Transportation Networks
We consider the problem of optimizing the locations of source nodes in
transportation networks. A reduction of the fraction of surplus nodes induces a
glassy transition. In contrast to most constraint satisfaction problems
involving discrete variables, our problem involves continuous variables which
lead to cavity fields in the form of functions. The one-step replica symmetry
breaking (1RSB) solution involves solving a stable distribution of functionals,
which is in general infeasible. In this paper, we obtain small closed sets of
functional cavity fields and demonstrate how functional recursions are
converted to simple recursions of probabilities, which make the 1RSB solution
feasible. The physical results in the replica symmetric (RS) and the 1RSB
frameworks are thus derived and the stability of the RS and 1RSB solutions are
examined.Comment: 38 pages, 18 figure
Coherence of Nitrogen-Vacancy Electronic Spin Ensembles in Diamond
We present an experimental and theoretical study of electronic spin
decoherence in ensembles of nitrogen-vacancy (NV) color centers in bulk
high-purity diamond at room temperature. Under appropriate conditions, we find
ensemble NV spin coherence times (T_2) comparable to that of single NVs, with
T_2 > 600 microseconds for a sample with natural abundance of 13C and
paramagnetic impurity density ~10^15 cm^(-3). We also observe a sharp decrease
of the coherence time with misalignment of the static magnetic field relative
to the NV electronic spin axis, consistent with theoretical modeling of NV
coupling to a 13C nuclear spin bath. The long coherence times and increased
signal-to-noise provided by room-temperature NV ensembles will aid many
applications of NV centers in precision magnetometry and quantum information.Comment: 5 pages, 3 figures; v2 minor correction
Observing two dark accelerators around the Galactic Centre with Fermi Large Area Telescope
We report the results from a detailed ray investigation in the field
of two "dark accelerators", HESS J1745-303 and HESS J1741-302, with years
of data obtained by the Fermi Large Area Telescope. For HESS J1745-303, we
found that its MeV-GeV emission is mainly originated from the "Region A" of the
TeV feature. Its ray spectrum can be modeled with a single power-law
with a photon index of from few hundreds MeV to TeV. Moreover,
an elongated feature, which extends from "Region A" toward northwest for
, is discovered for the first time. The orientation of this
feature is similar to that of a large scale atomic/molecular gas distribution.
For HESS J1741-302, our analysis does not yield any MeV-GeV counterpart for
this unidentified TeV source. On the other hand, we have detected a new point
source, Fermi J1740.1-3013, serendipitously. Its spectrum is apparently curved
which resembles that of a ray pulsar. This makes it possibly
associated with PSR B1737-20 or PSR J1739-3023.Comment: 11 pages, 7 figures, 2 tables, accepted for publication in MNRA
Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac
Intracellular cAMP and serotonin are important modulators of anxiety and depression. Fluoxetine, a selective serotonin reuptake inhibitor (SSRI) also known as Prozac, is widely used against depression, potentially by activating cAMP response element-binding protein (CREB) and increasing brain-derived neurotrophic factor (BDNF) through protein kinase A (PKA). However, the role of Epac1 and Epac2 (Rap guanine nucleotide exchange factors, RAPGEF3 and RAPGEF4, respectively) as potential downstream targets of SSRI/cAMP in mood regulations is not yet clear. Here, we investigated the phenotypes of Epac1 (Epac1− / −) or Epac2 (Epac2− / −) knockout mice by comparing them with their wild-type counterparts. Surprisingly, Epac2− / − mice exhibited a wide range of mood disorders, including anxiety and depression with learning and memory deficits in contextual and cued fear-conditioning tests without affecting Epac1 expression or PKA activity. Interestingly, rs17746510, one of the three single-nucleotide polymorphisms (SNPs) in RAPGEF4 associated with cognitive decline in Chinese Alzheimer’s disease (AD) patients, was significantly correlated with apathy and mood disturbance, whereas no significant association was observed between RAPGEF3 SNPs and the risk of AD or neuropsychiatric inventory scores. To further determine the detailed role of Epac2 in SSRI/serotonin/cAMP-involved mood disorders, we treated Epac2− / − mice with a SSRI, Prozac. The alteration in open field behavior and impaired hippocampal cell proliferation in Epac2− / − mice were alleviated by Prozac. Taken together, Epac2 gene polymorphism is a putative risk factor for mood disorders in AD patients in part by affecting the hippocampal neurogenesis.published_or_final_versio
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