Achieving partnering success through an incentive agreement : lessons learned from an underground railway extension project in Hong Kong

Author name used in this publication: Linda C. N. FanAuthor name used in this publication: John F. Y. Yeung2008-2009 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

Fuzzy set theory approach for measuring the performance of relationship-based construction projects in Australia

Author name used in this manuscript: John F. Y. Yeung2011-2012 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

Defining relational contracting from the Wittgenstein family-resemblance philosophy

Author name used in this publication: John F.Y. Yeung2011-2012 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

Concentration effect on construction firms : tests of resource partitioning theory in Jiangsu Province (China) from 1989 to 2007

Author name used in this manuscript: John F. Y. Yeung2011-2012 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

Critical analysis of partnering research trend in construction journals

Author name used in this manuscript: John F. Y. Yeung2011-2012 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

Developing a fuzzy risk assessment model for guaranteed maximum price and target cost contracts in construction

Author name used in this publication: Patrick T. I. LamAuthor name used in this publication: John F. Y. Yeung2010-2011 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

Risk ranking and analysis in target cost contracts : empirical evidence from the construction industry

Author name used in this publication: Patrick T.I. LamAuthor name used in this publication: John F.Y. Yeung2011-2012 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

Developing a benchmarking model for construction projects in Hong Kong

Author name used in this manuscript: John F. Y. YeungAuthor name used in this manuscript: Y. H. Chiang2012-2013 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

Comparative Pathogenesis of Three Human and Zoonotic SARS-CoV Strains in Cynomolgus Macaques

The severe acute respiratory syndrome (SARS) epidemic was characterized by increased pathogenicity in the elderly due to an early exacerbated innate host response. SARS-CoV is a zoonotic pathogen that entered the human population through an intermediate host like the palm civet. To prevent future introductions of zoonotic SARS-CoV strains and subsequent transmission into the human population, heterologous disease models are needed to test the efficacy of vaccines and therapeutics against both late human and zoonotic isolates. Here we show that both human and zoonotic SARS-CoV strains can infect cynomolgus macaques and resulted in radiological as well as histopathological changes similar to those seen in mild human cases. Viral replication was higher in animals infected with a late human phase isolate compared to a zoonotic isolate. While there were significant differences in the number of host genes differentially regulated during the host responses between the three SARS-CoV strains, the top pathways and functions were similar and only apparent early during infection with the majority of genes associated with interferon signaling pathways. This study characterizes critical disease models in the evaluation and licensure of therapeutic strategies against SARS-CoV for human use