231 research outputs found
The Relation between the Minute Content of Uranium in Zircon and its Mineralogical Characters
Verification of criterion-related validity of the evaluation method of postural stability using the frame subtraction method.
It is important to quantify the postural stability. The frame subtraction method can calculate the motions of a subject, and might be easier to implement, with lower costs. However, validity of the evaluation of postural stability using this method have not been validated yet. Therefore, the purpose of this study was to verify criterion-related validity of the frame subtraction scores and the center of pressure (COP) parameters during maintenance of single leg standing. Twenty two healthy young subjects participated in this study. Motion tasks comprised right leg standing with eyes open and closed. The total length of COP displacements (LNG), Root mean square (RMS) area, anterior - posterior (AP) range, medial - lateral (ML) range were recorded using the force plate. Simultaneously, the motion images were acquired with digital video cameras from the front and right sides. After the motion images were analyzed using the frame subtraction method, the frame subtraction scores (maximumsum of the frame subtraction score on each planethe frontal and sagittal planes) were measured. To confirm the validity, Spearman's rank correlation coefficient between the frame subtraction scores and the COP parameters was calculated. The sum of the frame subtraction score on the frontal plane was significantly correlated with all COP displacements in the single leg standing. The result of this study indicated that the frame subtraction method could be applied to the evaluation of balance task with postural sway such as maintenance of single leg standing. The frame subtraction method is low cost and easy owing to its marker-less systems
Advances in measurement technology and intelligent instruments for manufacturing engineering
Perpendicular magnetic anisotropy at Fe/Au(111) interface studied by M\"{o}ssbauer, x-ray absorption, and photoemission spectroscopies
The origin of the interfacial perpendicular magnetic anisotropy (PMA) induced
in the ultrathin Fe layer on the Au(111) surface was examined using
synchrotron-radiation-based M\"{o}ssbauer spectroscopy (MS), X-ray magnetic
circular dichroism (XMCD), and angle-resolved photoemission spectroscopy
(ARPES). To probe the detailed interfacial electronic structure of orbital
hybridization between the Fe 3 and Au 6 bands, we detected the
interfacial proximity effect, which modulates the valence-band electronic
structure of Fe, resulting in PMA. MS and XMCD measurements were used to detect
the interfacial magnetic structure and anisotropy in orbital magnetic moments,
respectively. - ARPES also confirms the initial growth of Fe on large
spin-orbit coupled surface Shockley states under Au(111) modulated electronic
states in the vicinity of the Fermi level. This suggests that PMA in the
Fe/Au(111) interface originates from the cooperation effects among the spin,
orbital magnetic moments in Fe, and large spin-orbit coupling in Au. These
findings pave the way to develop interfacial PMA using - hybridization
with a large spin-orbit interaction
Physiological and Pathological Mitochondrial Clearance Is Related to Pectoralis Major Muscle Pathogenesis in Broilers With Wooden Breast Syndrome
Wooden breast syndrome (WB) constitutes an emerging myopathy in the pectoralis major muscle (PM) of broiler chickens, characterized by myofiber hypertrophy and degeneration along with severe fibrosis. WB pathogenesis has been considered to involve hypoxia induced by rapid growth of the PM. In this study, we focused on mitochondrial morphology and dynamics in the myofibers, as these organelles are sensitive to damage by hypoxia, and examined the effects on WB pathogenesis. Specifically, the PMs of a flock of 35 broilers at 50 days of age were evaluated. First, the severity of disease in each bird was determined by measuring histopathological indices including the fibrotic area (FA) in the muscle and circularity of myofibers (CM). These values were 29.4 ± 9.6% and 0.70 ± 0.042, respectively, showing variety among the flock. Myofiber vacuolization was observed in all birds including numerous small- or large-rimmed vacuoles, with the former consisting of ultrastructurally autophagosome-like vacuoles engulfing degenerated mitochondria. The large-rimmed vacuoles frequently occurred in the PMs with more severe FA and CM, indicating a relationship between altered autophagy/mitophagy and WB severity. Next, the expression levels of hypoxia-adaptive and mitochondrial dynamics-related genes were analyzed, and their correlations with the histopathological indices were examined. The histopathological indices were negatively correlated with the expression of vascular endothelial growth factor A (VEGFA), indicating that less angiogenesis owing to weakened hypoxia-inducible factor signaling induces more severe WB pathology. In addition, the observed negative correlation with mitochondrial dynamics-related genes implied that WB pathology deteriorates concomitant with reduced mitochondrial dynamics. Furthermore, the expression of mitochondrial dynamics-related genes showed strong positive correlation with that of VEGFA and autophagy-/mitophagy-related genes. These results revealed that the PMs of broilers possess the mechanism of physiological clearance of mitochondria damaged by the hypoxia resulting from the continuous mitochondrial dynamics and autophagy/mitophagy accompanying rapid PM growth. In turn, the altered mitochondrial clearance induced by chronic hypoxia and the accumulation of damaged mitochondria likely underly the severe pathological features of WB.ArticleFrontiers in Pharmacology.11:579(2020)journal articl
A randomized, controlled, multicenter trial of the effects of antithrombin on disseminated intravascular coagulation in patients with sepsis
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