Which Factors Affect Dental Esthetics and Smile Attractiveness in Orthodontically Treated Patients?

Objectives: This study aimed to find the factors that affect dental esthetics and smile attractiveness in orthodontically treated patients according to laypeople’s judgment, and to determine whether there is any relationship between dental and smile esthetics. Materials and Methods: Using the Q-sort technique, 60 laypersons (30 males, 30 females) rated dental and smile photographs of 48 orthodontically treated patients based on their degree of attractiveness. Dental and smile parameters of each rated image were measured by Smile Analyzer software. The Student’s t-test and chi-square test were used to compare dental and smile parameters between attractive and unattractive images. The logistic regression was used to assess which variables predicted dental and smile esthetics in treated individuals. Results: The philtral to commissural height ratio and gingival display were significantly different in attractive and unattractive smiles (P=0.003 and P=0.02, respectively). None of the dental variables were found to be a determinant of dental esthetics at the end of the orthodontic treatment (P>0.05). According to the judgment of all raters (female and male) and the male raters’ judgment, smile attractiveness could be predicted by philtral to commissural height ratio and buccal corridor ratio (P0.05). Conclusion: The philtral to commissural height ratio and buccal corridor ratio can be considered as predictors of smile attractiveness in orthodontically treated patients. Achieving dental esthetics at the end of orthodontic treatment does not guarantee smile attractiveness

Inducible Clindamycin Resistant Staphylococcus aureus in Iran: A Systematic Review and Meta-analysis

<p><strong><em>Introduction</em></strong>: <em>S</em><em>taphylococcus aureus </em>is a prominent human pathogen. One of the drugs used in the treatment of staphylococcal infections (particularly infections of skin and soft tissue), is clindamycin. Resistance to clindamycin includes two types: inducible and constitutive. Routine laboratory methods of antibiotic susceptibility testing cannot detect the inducible type and D- test is required for its detection. The purpose of this systematic review was to determine the relative prevalence of this type of resistance in Iran.</p><p><strong><em>M</em></strong><strong><em>e</em></strong><strong><em>thods</em></strong>: Search terms "inducible clindamycin resistant", "D-test", "<em>Staphylococcus aureus</em>" and "Iran" were used to find relevant articles in PubMed, Google Scholar and two Persian search engines. Also, the abstracts of the recent national microbiology congresses were checked.All studies used D-test to find iMLSB  (inducible macrolide, lincosamide and streptograminB resistance) phenotype among clinical isolates (not nasal swabs) of <em>S. aureus</em>, were included. In order to perform meta-analysis, we used “comprehensive meta-analysis” software (ver. 2).</p><p><strong><em>Results</em></strong>: In total, 9 articles and 8 abstracts related to the topic of the study were found. Random effects meta-analyses showed a pooled estimate for percentage of iMLSB  phenotype among 2683 samples of <em>S. aureus </em>was about 10% (95% confidence interval: 0.07-0.12). Using the fixed effect model, the odds of positive iMLSB  in methicillin-resistant <em>S. aureus </em>was about 5 times more likely to occur in comparison with methicillin-susceptible <em>S. aureus </em>(95% CI: 3.49 to 7.76).</p><p><strong><em>Conclusion</em></strong>: Fortunately, the relative frequency of inducible resistance to clindamycin in our country is relatively low. However, we believe that D-test should be performed for all erythromicin-resistant  isolates  in  order  to  identify  inducible  resistance  to  clindamycin.Moreover, reevaluation of inducible reistance to clindamycin in forthcoming years is highly recommended.</p