Research on Dynamic Response of Anchored Jointed Rock Slope under Traffic Load

Based on the actual slope engineering, the dynamic response characteristics of the anchored joint slope in acceleration, velocity, and anchorage cable axial force under traffic load are numerically simulated. The results show that the cable axial force of the anchored slope starts to rise from the anchor head under traffic load, reaches a stable value in the free section, and falls to close to zero in the anchorage section. The axial force of the anchorage cable decreases when the slope height increases. Within the free section of the anchorage cable, there is a "small platform", where the axial force value decreases slightly and rises again, and its position corresponds to the range in which the anchorage cable passes through the joint. The dynamic response of traffic loads to the monitoring points of the slope is related to the magnitude of the load, the frequency, and the duration of the vibration. It is also related to the distance from the location of the traffic load, the physical and mechanical parameters of the location, the existence of joints, cracks and other structural planes, and whether or not to take support measures. When the frequency of the traffic load is close to the natural frequency of the slope, the resonance phenomenon is easy to occur, and the damage of the rock and soil of the slope is increased

Research on Fatigue Damage and Affecting Factors of Defected Rock Mass Based on Ultrasonic Wave Velocity

In this paper the fatigue-loading test of defected rock-like specimen has been carried out by electro-hydraulic servo fatigue testing machine. At the same time, the ultrasonic data has been collected and analyzed by the digital ultrasonic instrument. The fatigue damage and influencing factors of the defective rock mass under dynamic load are studied. According to the experimental research and analysis, this paper chooses to define the damage variable by ultrasonic velocity, and the inverse function of the Logistic equation was used to describe the evolution curve of fatigue damage sample. The experimental data fitting results show that the damage model and the experimental data fit well. In addition, this paper analyzes the main influencing factors of fatigue damage in the test. The initial damage represents the damage state before the sample is cyclically loaded. Different initial damages have a significant effect on the fatigue life of the sample. In the case the initial damage is substantially the same, the upper limit stress is larger, the fatigue life of the sample is shorter, and conversely, the fatigue life is longer

SAA1 identified as a potential prediction biomarker for metastasis of hepatocellular carcinoma via multi-omics approaches

BackgroundMetastasis is the major cause of high recurrence and mortality of hepatocellular carcinoma (HCC). Unfortunately, there are few reports on effective biomarkers of HCC metastasis. Previous studies have reported that SAA1 may be a predictor and prognostic biomarker for multiple malignant tumors. However, the role of SAA1 in HCC has not yet been investigated.MethodsWe applied RNA sequencing and proteomics analysis to investigate the expression landscape of HCC cell lines and patient serum, respectively. SAA1 is a common key gene and listed as a candidate biomarker of HCC metastasis. It was validated in two cell lines, 107 participants serum, and 63 matched HCC and adjacent non-tumorous liver tissues. Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx), and The Cancer Genome Atlas (TCGA) datasets were integrated to explore SAA1 expression among various cell types and organs. The diagnostic and prognostic value of SAA1 in HCC were determined through receiver operating characteristic (ROC) and Kaplan–Meier curves. Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis, and protein-protein interaction (PPI) network were constructed for SAA1, as well as for its co−expressed genes. We further analyzed the correlation between SAA1 and co-expression genes.ResultsWe found 7 differentially expressed genes (DEGs) and 14 differentially expressed proteins (DEPs) were related to HCC metastasis. SAA1, a key candidate biomarker, was highly enriched in hepatocytes and liver organ, and it was also highly expressed in HCC cells and the serum and tissues of HCC patients. The results of ROC curve analysis indicated that SAA1 had better predictive values for distinguishing HCC metastasis from non-metastasis. Kaplan-Meier curve analysis revealed that HCC patients with higher SAA1 expression had worse overall survival.ConclusionsOur findings provide new insights into HCC metastasis by identifying candidate gene prediction biomarkers for HCC metastasis

An Overview on Total Valorization of Litsea cubeba as a New Woody Oil Plant Resource toward a Zero-Waste Biorefinery

With the increasing global demand for edible oils and the restriction of arable land minimum in China, woody oil plants have gradually become the optimal solution to cover the shortage of current edible oil supply and to further improve the self-sufficiency rate. However, due to the lack of knowledge and technique, problems like “how to make full use of these plant resources?” and “how to guide consumers with reasonable data?” limit the development of woody oilseed industry towards a sustainable circular economy. In this review, several emerging unique woody oil plants in China were introduced, among which Litsea cubeba as a new woody oil plant was highlighted as a reference case based on its current research progress. Unlike other woody oil plants, essential oil rather than oil from Litsea cubeba has always been the main product through the years due to its interesting biological activities. Most importantly, its major component, citral, could be the base for other synthesized perfume compounds with added value. Moreover, the sustainable biorefinery of large amounts of waste residual after Litsea cubeba essential oil processing is now technically feasible, which could inspire a total valorization pathway for other woody oil plants to make more competitive plant-based products with both economic, social, and ecological benefits

Flower-Like Dual-Defective Z-Scheme Heterojunction g-C3N4/ZnIn2S4 High-Efficiency Photocatalytic Hydrogen Evolution and Degradation of Mixed Pollutants

Graphitic carbon nitride (g-C3N4) with a porous nano-structure, nitrogen vacancies, and oxygen-doping was prepared by the calcination method. Then, it was combined with ZnIn2S4 nanosheets containing zinc vacancies to construct a three-dimensional (3D) flower-like Z-scheme heterojunction (pCN-N/ZIS-Z), which was used for photocatalytic hydrogen evolution and the degradation of mixed pollutants. The constructed Z-scheme heterojunction improved the efficiency of photogenerated charges separation and migration, and the large surface area and porous characteristics provided more active sites. Doping and defect engineering can change the bandgap structure to improve the utilization of visible light, and can also capture photogenerated electrons to inhibit recombination, so as to promote the use of photogenerated electron-hole pairs in the photocatalytic redox process. Heterojunction and defect engineering synergized to form a continuous and efficient conductive operation framework, which achieves the hydrogen production of pCN-N/ZIS-Z (9189.8 µmol·h−1·g−1) at 58.9 times that of g-C3N4 (155.9 µmol·h−1·g−1), and the degradation rates of methyl orange and metronidazole in the mixed solution were 98.7% and 92.5%, respectively. Our research provides potential ideas for constructing a green and environmentally friendly Z-scheme heterojunction catalyst based on defect engineering to address the energy crisis and environmental restoration

Effects of alkali activator on the chloride-ion permeability of one-part alkali-activated nickel slag concrete

Herein, the effects of the ionic types and content of alkali activator on the chloride-ion permeability of one-part alkali-activated nickel slag concrete were examined. The NT Build 492 method was adopted to measure the Cl− transport performance. In general, the total Cl− concentration in concrete decreases with the increase of penetration depth; however, the enrichment of Cl− concentration in the sample is not obvious. Anions have more effect on 28-d compressive strength, while cations have more effect on chlorine-ion permeability. For the same Na2O content, SiO32−-activator and Na+-activator perform better than other anions and cations, while OH– and K+ perform worse than other ions. The chloride-ion permeability coefficient (DRCM) of concrete with Na2SiO3 is the lowest and that with KOH is the highest. The DRCM of concrete prepared with KOH is 1.93 times higher than that of concrete prepared with Na2SiO3. When the activator is Na2SiO3, the DRCM of concrete decreases with the increase in Na2O content when the Na2O content is less than 7%. However, when the Na2O content exceeds 7%, the DRCM of concrete increases with the increase in Na2O content