Pleuritis in 25 year old Female with Systemic Lupus Erythromatosus: Case Report

Systemic lupus erythematosus (SLE) is a complex and multi-faceted disease that affects various organs of the human body and is predominantly seen in young group and females. The patient was a 25-year-old woman, According to the history taking from the patient, she suffered from progressive weakness and narcosis so that she was unable to walk and perform daily work at the time of the visit. In our examination, the young woman was lean and pale, with Icterus, body mass index of 22 and normal thyroid tests. Vital signs on admission were as follows: BP:10/7, PR:92, RR:20, T:38.5. In the heart examination, the heart sounds were normal and there was no heart murmur and additional sounds. In echocardiography for the patient, EF was 60%. Chest X-ray revealed pleural effusion for the patient. CT scans did not confirm the involvement of lung parenchyma and bilateral mild pleural effusion and pericardial effusion for the patient. The pleural fluid was evacuated under ultrasound.. Autoimmune examination results determined the diagnosis of SLE for the patien

Evaluation of hematological parameters alterations in different waves of COVID-19 pandemic: A cross-sectional study.

BackgroundThe occurrence of variations in routine hematological parameters is closely associated with disease progression, the development of severe illness, and the mortality rate among COVID-19 patients. This study aimed to investigate hematological parameters in COVID-19 hospitalized patients from the 1st to the 5th waves of the current pandemic.MethodsThis cross-sectional study included a total of 1501 hospitalized patients with laboratory-confirmed COVID-19 based on WHO criteria, who were admitted to Shahid Sadoughi Hospital (SSH) in Yazd, Iran, from February 2020 to September 2021. Throughout, we encountered five COVID-19 surge waves. In each wave, we randomly selected approximately 300 patients and categorized them based on infection severity during their hospitalization, including partial recovery, full recovery, and death. Finally, hematological parameters were compared based on age, gender, pandemic waves, and outcomes using the Mann-Whitney U and Kruskal-Wallis tests.ResultsThe mean age of patients (n = 1501) was 61.1±21.88, with 816 (54.3%) of them being men. The highest mortality in this study was related to the third wave of COVID-19 with 21.3%. There was a significant difference in all of the hematological parameters, except PDW, PLT, and RDW-CV, among pandemic waves of COVID-19 in our population. The highest rise in the levels of MCV and RDW-CV occurred in the 1st wave, in the 2nd wave for lymphocyte count, MCHC, PLT count, and RDW-SD, in the 3rd wave for WBC, RBC, neutrophil count, MCH, and PDW, and in the 4th wave for Hb, Hct, and ESR (p ConclusionThe findings of our study unveiled notable variations in hematological parameters across different pandemic waves, gender, and clinical outcomes. These findings indicate that the behavior of different strains of the COVID-19 may differ across various stages of the pandemic