Analyses of pion-nucleon elastic scattering amplitudes up to O(p4)O(p^4) in extended-on-mass-shell subtraction scheme

We extend the analysis of elastic pion-nucleon scattering up to $O(p^4)$ level using extended-on-mass-shell subtraction scheme within the framework of covariant baryon chiral perturbation theory. Numerical fits to partial wave phase shift data up to $\sqrt{s}=1.13$ GeV are performed to pin down the free low energy constants. A good description to the existing phase shift data is achieved. We find a good convergence for the chiral series at $O(p^4)$, considerably improved with respect to the $O(p^3)$-level analyses found in previous literature. Also, the leading order contribution from explicit $\Delta(1232)$ resonance and partially-included $\Delta(1232)$ loop contribution are included to describe phase shift data up to $\sqrt{s}=1.20$ GeV. As phenomenological applications, we investigate chiral correction to the Goldberger-Treiman relation %$\Delta_{GT}$ and find that it converges rapidly, and the $O(p^3)$ correction is found to be very small: $\simeq 0.2$. We also get a reasonable prediction of pion-nucleon sigma term $\sigma_{\pi N}$ up to $O(p^4)$ by performing fits including both the pion-nucleon partial wave phase shift data and the lattice QCD data. We report that $\sigma_{\pi N}=52\pm7$ MeV from the fit without $\Delta(1232)$, and $\sigma_{\pi N}=45\pm6$ MeV from the fit with explicit $\Delta(1232)$.Comment: The final version published in Phys.Rev. D 87, 054019 (2013

Pole analysis on the hadron spectroscopy of Λb→J/ΨpK−\Lambda_b\to J/\Psi p K^-

In this paper we study the $J/\Psi p$ spectroscopy in the process of $\Lambda_b\to J/\Psi p K^-$. The final state interactions of coupled channel $J/\Psi p$ ~-~ $\bar{D} \Sigma_c$~-~$\bar{D}^{*} \Sigma_c$ are constructed based on K-matrix with the Chew-Mandelstam function. We build the $\Lambda_b\to J/\Psi p K^-$ amplitude according to the Au-Morgan-Pennington method. The event shape is fitted and the decay width of $\Lambda_b\to J/\Psi p K^-$ is used to constrain the parameters, too. With the amplitudes we extract out the poles and their residues. Our amplitude and pole analysis suggest that the $P_c(4312)$ should be $\bar{D}\Sigma_c$ molecule, the $P_c(4440)$ could be an S-wave compact pentaquark state, and the structure around $P_c(4457)$ is caused by the cusp effect. The future experimental measurement of the decays of $\Lambda_b\to \bar{D}\Sigma_c K^-$ and $\Lambda_b\to \bar{D}^*\Sigma_c K^-$ would further help to study the nature of these resonances.Comment: updated to the published versio

Effect of Gamma Irradiation on Microcrystalline Structure of Phragmites Cellulose

Effect of 60Co-γ irradiation treatment on cellulose structure originating from Phragmites communis trim (PCT) was investigated on the basis of irradiation doses of 0 to 2000 kGy at a dose rate of 2 kGy h-1. Scanning electron micrograph images showed that surface morphologies of PCT cellulose could become fragmented after being treated with 60Co-γ irradiation. Based on X-ray diffraction profiles, crystallinity and amorphous region of microcrystalline cellulose treated by irradiation were obviously changed. Fourier transform IR spectroscopy data indicated that a new characteristic peak corresponding to carbonyl (1734 cm -1) appeared after PCT cellulose was treated with 60Co-γ irradiation, which suggested that PCT cellulose was degraded after irradiation treatment

Nodal Promotes Glioblastoma Cell Growth

Nodal is a member of the transforming growth factor-β (TGF-β) superfamily that plays critical roles during embryogenesis. Recent studies in ovarian, breast, prostate, and skin cancer cells suggest that Nodal also regulates cell proliferation, apoptosis, and invasion in cancer cells. However, it appears to exert both tumor-suppressing and tumor-promoting effects, depending on the cell type. To further understand the role of Nodal in tumorigenesis, we examined the effect of Nodal in glioblastoma cell growth and spheroid formation using U87 cell line. Treatment of U87 with recombinant Nodal significantly increased U87 cell growth. In U87 cells stably transfected with the plasmid encoding Nodal, Smad2 phosphorylation was strongly induced and cell growth was significantly enhanced. Overexpression of Nodal also resulted in tight spheroid formation. On the other hand, the cells stably transfected with Nodal siRNA formed loose spheroids. Nodal is known to signal through activin receptor-like kinase 4 (ALK4) and ALK7 and the Smad2/3 pathway. To determine which receptor and Smad mediate the growth promoting effect of Nodal, we transfected siRNAs targeting ALK4, ALK7, Smad2, or Smad3 into Nodal-overexpressing cells and observed that cell growth was significantly inhibited by ALK4, ALK7, and Smad3 siRNAs. Taken together, these findings suggest that Nodal may have tumor-promoting effects on glioblastoma cells and these effects are mediated by ALK4, ALK7, and Smad3

Surgical treatment of multivalvular endocarditis: Twenty-one–year single center experience

ObjectiveLittle information is available about surgical outcomes in patients with multivalvular endocarditis. The aim of this article is to review the 21-year experience with surgical treatment of patients with multivalvular endocarditis at our institution and, in particular, to determine the incidence, pathologic status, diagnosis, surgical strategies, and outcomes of patients with this disease.MethodsFrom January 1986 to December 2006, a total of 48 patients (40 men, 8 women), with a mean age of 42 ± 12 years, underwent surgery for multivalvular endocarditis. Endocarditis was active in 32 patients and healed in 16. Preoperative transthoracic echocardiographic evaluation was performed in all 48 patients with addition of transesophageal echocardiography in 22 (45.8%). Intraoperative findings showed that the endocarditis involved mostly the mitral and aortic valves (40/48 patients). Triple or quadruple valve involvement was found in 1 and 2 patients, respectively. Preoperative, perioperative, and postoperative data were retrospectively analyzed and risk factors for early and late survival were determined.ResultsIn only 24 (50.0%) patients was multivalvular endocarditis diagnosed by preoperative transthoracic echocardiography; 17 (77.3%) patients had multivalvular endocarditis confirmed by preoperative transesophageal echocardiography. The 30-day hospital mortality was 12.5% (n = 6). Preoperative renal failure, New York Heart Association class IV, and emergency surgery were identified as independent risk factors for hospital mortality. Overall long-term survival was 74% ± 6% at 5 years and 62% ± 3% at 10 years. Multivariate analysis revealed that renal failure and recurrent endocarditis were associated with increased late mortality. Ten-year freedom from recurrent endocarditis was 74% ± 5% and 10-year freedom from reoperation was 73% ± 6%.ConclusionsIn our institution, multivalvular endocarditis was diagnosed by transthoracic echocardiography in only half of the patients. Intraoperative transesophageal echocardiography provided a more effective means to identify this disease. Radical resection of all infected tissues for patients with multivalvular endocarditis and additional intraoperative interventions, depending on the intraoperative pathologic condition, produced satisfactory in-hospital and long-term results, similar to those in patients with a single infected heart valve

Research Progress on Flavor Substances of Rice and Its Derivatives

As the main grain product in China， the flavor and quality of rice have attracted much attention.Different varieties or different producing areas may give rice unique flavor. The current methods of extracting rice flavor compounds (SAFE， SDE， SPME， P&T， SFE， etc.) were compared. The mechanism of producing rice flavor substances was discussed. Different rice varieties， growth environment， storage conditions， amylose content， cooking method， soaking time and so on would affect rice flavor， but the relationship between volatile matter and aroma is still not clear. However， 2-AP is generally considered to be a marker to distinguish aromatic rice from non aromatic rice. At the same time， the flavor compounds，processing methods， production mechanism and other thing of some rice derived foods were also listed. It provides a certain reference and theoretical basis for the recovery and application of rice flavor substances

A novel model for hemolysis estimation in rotating impeller blood pumps considering red blood cell aging

For blood pumps with a rotating vane-structure, hemolysis values are estimated using a stress-based power-law model. It has been reported that this method does not consider the red blood cell (RBC) membrane’s shear resistance, leading to inaccurate estimation of the hemolysis value. The focus of this study was to propose a novel hemolysis model which can more accurately predict the hemolysis value when designing the axial flow blood pump. The movement behavior of a single RBC in the shear flow field was simulated at the mesoscale. The critical value of shear stress for physiological injury of RBCs was determined. According to the critical value, the equivalent treatment of RBC aging was studied. A novel hemolysis model was established considering the RBC’s aging and the hemolysis’ initial value. The model’s validity was verified under the experimental conditions of shear stress loading and the conditions of the shear flow field of the blood pump. The results showed that compared with other hemolysis models for estimating the hemolysis value of blood pumps, the novel hemolysis model proposed in this paper could effectively reduce the estimation error of the hemolysis value and provide a reference for the optimal design of rotary vane blood pumps

Jets in a Gamma-Ray Burst During its Prompt Emission: Evolution of Lorentz Factor

Knowledge about the Lorentz factor and its evolution of relativistic jets in gamma-ray bursts (GRBs) is crucial to understand their physics. An exact value of bulk Lorentz factor can be estimated based on a high-energy spectral cutoff, which may appear in GRBs' prompt emission owing to the absorption of photon-photon pair production. In this work, we focus on the investigation of the bulk Lorentz factor evolution of jets in an individual burst. Based on \textsl{Fermi} observations, we search for the bursts with multiple $\gamma$-ray pulses characterized by a high-energy spectral cutoff, and nine GRBs are obtained. Together with the estimation of the pulse duration and radiation spectrum, the Lorentz factor of jets corresponding to different pulses in an individual GRB are estimated. It is shown that the Lorentz factor of jets in an individual GRB fluctuates within a certain range and without a general trend in these nine GRBs. In addition, the Lorentz factors of the jets in GRBs~130821A, 160509A and 160625B seem to increase with time. We also study the relations among $L_{\rm iso }$, $E_{\rm p,z}$, and $\Gamma$ for the pulses in our sample, which is found to be consistent with that found in previous works.Comment: Accepted for publication in Ap

Retrospective analysis for thirty-nine patients with solitary fibrous tumor of pleura and review of the literature

<p>Abstract</p> <p>Background</p> <p>Solitary fibrous tumor of the pleura (SFTP) is an uncommon neoplasm arising from mesenchymal cells. The aim of this study is to summarize the experience and the outcome of the surgical treatment for 39 cases of SFTP.</p> <p>Methods</p> <p>From January 2004 to December 2008, 39 patients underwent surgical resection of SFTP in our department. All patients had clinical follow-up by the same team of surgeons. The mean follow-up was 40.3 months.</p> <p>Results</p> <p>A local removal of the neoplasm was accomplished by video-assisted thoracic surgery (VATS) in 9 patients (group A) and by thoracotomy in 30 patients (group B) respectively. Comparing with group B, operations in group A took significantly less operative time, blood loss and spent less time in the intensive care unit and hospital. All specimens were positive for CD34 and Bcl-2. One patient developed recurrence, and the remaining 38 patients are alive and disease free at the end of follow-up.</p> <p>Conclusions</p> <p>Malignant SFTP still had the potential recurrence. VATS represents the more acceptable choice for the selected patients with SFTP.</p