3,909 research outputs found

    Energy Efficient Ant Colony Algorithms for Data Aggregation in Wireless Sensor Networks

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    In this paper, a family of ant colony algorithms called DAACA for data aggregation has been presented which contains three phases: the initialization, packet transmission and operations on pheromones. After initialization, each node estimates the remaining energy and the amount of pheromones to compute the probabilities used for dynamically selecting the next hop. After certain rounds of transmissions, the pheromones adjustment is performed periodically, which combines the advantages of both global and local pheromones adjustment for evaporating or depositing pheromones. Four different pheromones adjustment strategies are designed to achieve the global optimal network lifetime, namely Basic-DAACA, ES-DAACA, MM-DAACA and ACS-DAACA. Compared with some other data aggregation algorithms, DAACA shows higher superiority on average degree of nodes, energy efficiency, prolonging the network lifetime, computation complexity and success ratio of one hop transmission. At last we analyze the characteristic of DAACA in the aspects of robustness, fault tolerance and scalability.Comment: To appear in Journal of Computer and System Science

    On Input-to-State Stability of Impulsive Stochastic Systems with Time Delays

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    This paper is concerned with pth moment input-to-state stability (p-ISS) and stochastic input-to-state stability (SISS) of impulsive stochastic systems with time delays. Razumikhin-type theorems ensuring p-ISS/SISS are established for the mentioned systems with external input affecting both the continuous and the discrete dynamics. It is shown that when the impulse-free delayed stochastic dynamics are p-ISS/SISS but the impulses are destabilizing, the p-ISS/SISS property of the impulsive stochastic systems can be preserved if the length of the impulsive interval is large enough. In particular, if the impulse-free delayed stochastic dynamics are p-ISS/SISS and the discrete dynamics are marginally stable for the zero input, the impulsive stochastic system is p-ISS/SISS regardless of how often or how seldom the impulses occur. To overcome the difficulties caused by the coexistence of time delays, impulses, and stochastic effects, Razumikhin techniques and piecewise continuous Lyapunov functions as well as stochastic analysis techniques are involved together. An example is provided to illustrate the effectiveness and advantages of our results

    Study on the visible-light-induced photokilling effect of nitrogen-doped TiO2 nanoparticles on cancer cells

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    Nitrogen-doped TiO2 (N-TiO2) nanoparticles were prepared by calcining the anatase TiO2 nanoparticles under ammonia atmosphere. The N-TiO2 showed higher absorbance in the visible region than the pure TiO2. The cytotoxicity and visible-light-induced phototoxicity of the pure- and N-TiO2 were examined for three types of cancer cell lines. No significant cytotoxicity was detected. However, the visible-light-induced photokilling effects on cells were observed. The survival fraction of the cells decreased with the increased incubation concentration of the nanoparticles. The cancer cells incubated with N-TiO2 were killed more effectively than that with the pure TiO2. The reactive oxygen species was found to play an important role on the photokilling effect for cells. Furthermore, the intracellular distributions of N-TiO2 nanoparticles were examined by laser scanning confocal microscopy. The co-localization of N-TiO2 nanoparticles with nuclei or Golgi complexes was observed. The aberrant nuclear morphologies such as micronuclei were detected after the N-TiO2-treated cells were irradiated by the visible light

    Association of tissue lineage and gene expression: conservatively and differentially expressed genes define common and special functions of tissues

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    <p>Abstract</p> <p>Background</p> <p>Embryogenesis is the process by which the embryo is formed, develops, and establishes developmental hierarchies of tissues. The recent advance in microarray technology made it possible to investigate the tissue specific patterns of gene expression and their relationship with tissue lineages. This study is focused on how tissue specific functions, tissue lineage, and cell differentiation are correlated, which is essential to understand embryonic development and organism complexity.</p> <p>Results</p> <p>We performed individual gene and gene set based analysis on multiple tissue expression data, in association with the classic topology of mammalian fate maps of embryogenesis. For each sub-group of tissues on the fate map, conservatively, differentially and correlatively expressed genes or gene sets were identified. Tissue distance was found to correlate with gene expression divergence. Tissues of the ectoderm or mesoderm origins from the same segments on the fate map shared more similar expression pattern than those from different origins. Conservatively expressed genes or gene sets define common functions in a tissue group and are related to tissue specific diseases, which is supported by results from Gene Ontology and KEGG pathway analysis. Gene expression divergence is larger in certain human tissues than in the mouse homologous tissues.</p> <p>Conclusion</p> <p>The results from tissue lineage and gene expression analysis indicate that common function features of neighbor tissue groups were defined by the conservatively expressed genes and were related to tissue specific diseases, and differentially expressed genes contribute to the functional divergence of tissues. The difference of gene expression divergence in human and mouse homologous tissues reflected the organism complexity, i.e. distinct neural development levels and different body sizes.</p

    RF-thermal-structural-RF coupled analysis on the travelling wave disk-loaded accelerating structure

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    Travelling wave (TW) disk-loaded accelerating structure is one of the key components in normal conducting (NC) linear accelerators, and has been studied for many years. In the design process, usually after the dimensions of each cell and the two couplers are finalized, the structure is fabricated and tuned, and then the whole structure characteristics can be measured by the vector network analyzer. Before the structure fabrication, the whole structure characteristics are less simulated limited by the available computer capability. In this paper, we described the method to do the RF-thermal-structural-RF coupled analysis on the TW disk-loaded structure with one single PC. In order to validate our method, we first analyzed and compared our RF simulation results on the 3m long BEPCII structure with the corresponding experimental results, which shows very good consistency. Finally, the RF-thermal-structure-RF coupled analysis results on the 1.35m long NSC KIPT linac accelerating structure are presented.Comment: 5 pages, 16 figures, Submitted to the Chinese Physics C (Formerly High Energy Physics and Nuclear Physics

    FasL Gene–Deficient Mice Display a Limited Disruption in Spermatogenesis and Inhibition of Mono-(2-ethylhexyl) Phthalate–Induced Germ Cell Apoptosis

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    FasL (TNFSF6, CD95L) is hypothesized to trigger testicular germ cell apoptosis that normally occurs during a distinct peripubertal period as well as in response to toxicant-induced Sertoli cell injury. To test this hypothesis, we evaluated the testis of FasL gene–deficient mice (FasL−/−) at two distinct developmental ages (postnatal day [PND] 28 and 44) and after toxicant-induced Sertoli cell injury. Testicular cross sections from peripubertal (PND 28) FasL−/− mice showed significant increases in the basal germ cell apoptotic index (AI; 20.58 ± 4.59) as compared to the testis of C57BL/6J wild-type mice (5.16 ± 0.08) and closely correlated with increased expression of TRAIL protein in the testis of FasL−/− mice. A limited, but significant, number of seminiferous tubules in the testis of PND 28 FasL−/− mice showed a severe loss of germ cells with only Sertoli cells present. In contrast, no apparent gross histological changes were observed in the testis of adult (PND 44) FasL−/− mice. However, PND 44 FasL−/− mice did show a 51% reduction in homogenization-resistant elongate spermatids as compared to age-matched C57BL/6J mice. Exposure of PND 28 FasL−/− mice to mono-(2-ethylhexyl) phthalate (MEHP), a well-described Sertoli cell toxicant, unexpectedly caused a rapid decrease in the germ cell AI that paralleled increased levels of the CFLAR (c-FLIP) protein, a known inhibitor of death receptor signaling. In contrast, MEHP treatment did not decrease c-FLIP levels in PND 28 C57BL/6J mice. Taken together, these findings indicate that FasL protein expression is required during the peripubertal period for the proper regulation of germ cell apoptosis that occurs normally during this period. The influence of FasL on the cellular regulation of c-FLIP protein levels appears to be a unique mechanism for modulating germ cell apoptosis after toxicant-induced Sertoli cell injury

    The Study of Dust Formation of Six Tidal Disruption Events

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    This paper investigates eleven (UV-)optical-infrared (IR) spectral energy distributions (SEDs) of six tidal disruption events (TDEs), which are ASASSN-14li, ASASSN-15lh, ASASSN-18ul, ASASSN-18zj, PS18kh, and ZTF18acaqdaa. We find that all the SEDs show evident IR excesses. We invoke the blackbody plus dust emission model to fit the SEDs, and find that the model can account for the SEDs. The derived masses of the dust surrounding ASASSN-14li, ASASSN-15lh, ASASSN-18ul, ASASSN-18zj, PS18kh, and ZTF18acaqdaa are respectively 0.71.0(1.52.2)×104M\sim0.7-1.0\,(1.5-2.2)\times10^{-4}\,M_\odot, 0.63.1(1.46.3)×102M\sim0.6-3.1\,(1.4-6.3)\times10^{-2}\,M_\odot, 1.0(2.8)×104M\sim1.0\,(2.8)\times10^{-4}\,M_\odot, 0.11.6(0.33.3)×103M\sim0.1-1.6\,(0.3-3.3)\times10^{-3}\,M_\odot, 1.0(2.0)×103M\sim1.0\,(2.0)\times10^{-3}\,M_\odot, and 1.1(2.9)×103M\sim 1.1\,(2.9)\times10^{-3}\,M_\odot, if the dust is graphite (silicate). The temperature of the graphite (silicate) dust of the six TDEs are respectively 11401430(12101520)\sim1140-1430\,(1210-1520)\,K, 10301380(11001460)\sim1030-1380\,(1100-1460)\,K, 1530(1540)\sim1530\,(1540)\,K, 9601380(10201420)\sim960-1380\,(1020-1420)\,K, 900(950)\sim900\,(950)\,K, and 1600(1610)\sim1600\,(1610)\,K. By comparing the derived temperatures to the vaporization temperature of graphite (1900\sim 1900\,K) and silicate (11001500\sim 1100-1500\,K), we suggest that the IR excesses of PS18kh can be explained by both the graphite and silicate dust, the rest five TDEs favor the graphite dust while the silicate dust model cannot be excluded. Moreover, we demonstrate the lower limits of the radii of the dust shells surrounding the six TDEs are significantly larger than those of the radii of the photospheres at the first epochs of SEDs, indicating that the dust might exist before the the TDEs occurred.Comment: 13 pages, 4 figures, 4 tables, submitted to Ap
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