Fair Multiple-bank E-cash in the Standard Model

Multiple-bank e-cash (electronic cash) model allows users and merchants to open their accounts at different banks which are monitored by the Center Bank. Some multiple-bank e-cash systems were proposed in recent years. However, prior implementations of multiple-bank e-cash all require the random oracle model idealization in their security analysis. We know some schemes are secure in the random oracle model, but are trivially insecure under any instantiation of the oracle. In this paper, based on the automorphic blind signature, the Groth-Sahai proof system and a new group blind signature, we construct a fair multiple-bank e-cash scheme. The new scheme is proved secure in the standard model and provides the following functionalities, such as owner tracing, coin tracing, identification of the double spender and signer tracing. In order to sign two messages at once, we extend Ghadafi\u27s group blind signature to a new group blind signature. The new signature scheme may be of independent interest

Pyrimidine catabolism is required to prevent the accumulation of 5-methyluridine in RNA

5-Methylated cytosine is a frequent modification in eukaryotic RNA and DNA influencing mRNA stability and gene expression. Here we show that free 5-methylcytidine (5mC) and 5-methyl-2′-deoxycytidine are generated from nucleic acid turnover in Arabidopsis thaliana, and elucidate how these cytidines are degraded, which is unclear in eukaryotes. First CYTIDINE DEAMINASE produces 5-methyluridine (5mU) and thymidine which are subsequently hydrolyzed by NUCLEOSIDE HYDROLASE 1 (NSH1) to thymine and ribose or deoxyribose. Interestingly, far more thymine is generated from RNA than from DNA turnover, and most 5mU is directly released from RNA without a 5mC intermediate, since 5-methylated uridine (m5U) is an abundant RNA modification (m5U/U ∼1%) in Arabidopsis. We show that m5U is introduced mainly by tRNA-SPECIFIC METHYLTRANSFERASE 2A and 2B. Genetic disruption of 5mU degradation in the NSH1 mutant causes m5U to occur in mRNA and results in reduced seedling growth, which is aggravated by external 5mU supplementation, also leading to more m5U in all RNA species. Given the similarities between pyrimidine catabolism in plants, mammals and other eukaryotes, we hypothesize that the removal of 5mU is an important function of pyrimidine degradation in many organisms, which in plants serves to protect RNA from stochastic m5U modification

Estimation of mechanics parameters of rock in consideration of confining pressure using monitoring while drilling data

During the drilling process, high-strength rock can lead to various issues such as drilling suppression, bit wear, and increased operational costs. To ensure safe and efficient drilling operations, it is crucial to accurately predict the strength parameters of the rock and recommend modifications to operational procedures. This paper proposes a low-cost and fast measurement method for predicting the strength parameters of rock in the field. To evaluate the effectiveness of this method, a drilling process monitoring experiment was conducted on sandstone, limestone, and granite. The experiment studied the effect of confining pressure on the response of cutting with an impregnated diamond bit. By analyzing the relationship between the thrust force, torque force, and penetration depth under different confining pressures, the researchers developed an analytical model for drilling that considers confining pressure, compressed crushed zone, and bit geometry. The results show that the confining pressure has a significant effect on the cutting response. As the confining pressure increases, the thrust force, torque force, and penetration depth at the cutting point also increase. Furthermore, a new measurement method was proposed to determine the strength parameters, such as cohesion, internal friction angle, and unconfined compressive strength. The estimated strength parameters for the three rock types using the drilling method were in good agreement with those of the standard laboratory test, with an error range of 10%. This method of estimating rock strength parameters is a practical tool for engineers. It can continuously and quickly obtain the drilling parameters of in-situ rocks

Alteration of brain structural connectivity in progression of Parkinson's disease: A connectome-wide network analysis

Pinpointing the brain dysconnectivity in idiopathic rapid eye movement sleep behaviour disorder (iRBD) can facilitate preventing the conversion of Parkinson's disease (PD) from prodromal phase. Recent neuroimage investigations reported disruptive brain white matter connectivity in both iRBD and PD, respectively. However, the intrinsic process of the human brain structural network evolving from iRBD to PD still remains largely unknown. To address this issue, 151 participants including iRBD, PD and age-matched normal controls were recruited to receive diffusion MRI scans and neuropsychological examinations. The connectome-wide association analysis was performed to detect reorganization of brain structural network along with PD progression. Eight brain seed regions in both cortical and subcortical areas demonstrated significant structural pattern changes along with the progression of PD. Applying machine learning on the key connectivity related to these seed regions demonstrated better classification accuracy compared to conventional network-based statistic. Our study shows that connectome-wide association analysis reveals the underlying structural connectivity patterns related to the progression of PD, and provide a promising distinct capability to predict prodromal PD patients

Approaching an ultrafine microstructure and excellent tensile properties of a novel Er/Zr modified Al–7Si-0.6 Mg alloy fabricated by selective laser melting

In order to improve the mechanical properties of Al–Si alloys fabricated by selective laser melting process, the microstructure and mechanical properties of Er/Zr modified A357 (Al–7Si-0.6 Mg) alloy in as-built and stress relief annealing conditions were studied. The results show that adding 0.15 wt.% Er helps to refine the cellular size, which is formed by eutectic Si network. The (Al,Si)3(Er,Zr) phases were precipitated during the solidification of Er–Zr composite modified sample, which could act as inoculants to promote the formation of equiaxed grains and refine the grain size. The average grain size of 0.8Er-0.4Zr sample was only 3.1 ± 1.4 μm. The yield strength, tensile strength and elongation reached 333 ± 2 MPa, 454 ± 1 MPa and 12.5 ± 1%, respectively. After stress relief annealing, eutectic Si was spheroidized and its size was increased, resulting in a decrease of strength and an increase of elongation. At the same time, the nano-sized L12-structure particles were precipitated in the Er–Zr composite modified sample, which would make up for the loss of strength and level it up to a certain extent. Therefore, Er–Zr composite modification could be an effective method to improve the comprehensive mechanical properties of SLM processed Al–Si alloys