Quantum logical gates with four-level SQUIDs coupled to a superconducting resonator

We propose a way for realizing a two-qubit controlled phase gate with superconducting quantum interference devices (SQUIDs) coupled to a superconducting resonator. In this proposal, the two lowest levels of each SQUID serve as the logical states and two intermediate levels of each SQUID are used for the gate realization. We show that neither adjustment of SQUID level spacings during the gate operation nor uniformity in SQUID parameters is required by this proposal. In addition, this proposal does not require the adiabatic passage or a second-order detuning and thus the gate is much faster.Comment: 6 pages, 3 figure

T-cadherin deficiency increases vascular vulnerability in T2DM through impaired NO bioactivity.

BACKGROUND: Endothelial dysfunction plays a critical role in the development of type 2 diabetes (T2DM). T-cadherin (T-cad) has gained recognition as a regulator of endothelial cell (EC) function. The present study examined whether T-cad deficiency increases vascular vulnerability in T2DM. METHODS: Vascular segments were isolated from WT or T-cad knockout mice. Endothelial function, total NO accumulation, and the expression of T-cad related proteins were determined. RESULTS: Ach and acidified NaNO2 induced similar vasorelaxation in WT groups. T-cad KO mice exhibited normal response to acidified NaNO2, but manifested markedly reduced response to Ach. NO accumulation was also decreased in T-cad KO group. T-cad expression was reduced in WT mice fed 8 weeks of high fat diet (HFD). Furthermore, exacerbated reduction of vasorelaxation was observed in T-cad KO mice fed 8 weeks of HFD. CONCLUSIONS: In the current study, we provide the first in vivo evidence that T-cadherin deficiency causes endothelial dysfunction in T2DM vascular segments, suggesting the involvement of T-cad deficiency in T2DM pathogenesis

Weak decays of BcB_c into two hadrons under flavor SU(3) symmetry

A large number of $B_c$ meson events have been recorded at the LHCb detector, especially some two-body hadronic decay modes. We analyzed the weak decays of the $B_c$ meson into two hadron states under the flavor SU(3) symmetry. The relations among amplitudes of $B_c$ into $D+P(V)$, $B+P(V)$, $P(V)+P(V)$, $T_8+\bar T_8$ and $T_{10}+\bar T_{10}$ were investigated systematically, where $P$ ( $V$) denotes a light pseudoscalar (vector) meson and $T_{8,10}$ denotes a light baryon. The $\eta-\eta'$ mixing and $\omega-\phi$ mixing effects are also considered for the phenomenological discussions. We obtained the relations among decay widths of different $B_c$ decay channels. These results are helpful to study the two-body decay properties of the $B_c$ meson and test the flavor SU(3) symmetry.Comment: 11 pages, 1 figure and 10 tables. To be published in EPJ