Understanding and Diagnosing Visual Tracking Systems

Several benchmark datasets for visual tracking research have been proposed in recent years. Despite their usefulness, whether they are sufficient for understanding and diagnosing the strengths and weaknesses of different trackers remains questionable. To address this issue, we propose a framework by breaking a tracker down into five constituent parts, namely, motion model, feature extractor, observation model, model updater, and ensemble post-processor. We then conduct ablative experiments on each component to study how it affects the overall result. Surprisingly, our findings are discrepant with some common beliefs in the visual tracking research community. We find that the feature extractor plays the most important role in a tracker. On the other hand, although the observation model is the focus of many studies, we find that it often brings no significant improvement. Moreover, the motion model and model updater contain many details that could affect the result. Also, the ensemble post-processor can improve the result substantially when the constituent trackers have high diversity. Based on our findings, we put together some very elementary building blocks to give a basic tracker which is competitive in performance to the state-of-the-art trackers. We believe our framework can provide a solid baseline when conducting controlled experiments for visual tracking research

The impact of sea level rise on developing countries : a comparative analysis

Sea level rise (SLR) due to climate change is a serious global threat. The scientific evidence is now overwhelming. Continued growth of greenhouse gas emissions and associated global warming could well promote SLR of 1m-3m in this century, and unexpectedly rapid breakup of the Greenland and West Antarctic ice sheets might produce a 5m SLR. In this paper, the authors have assessed the consequences of continued SLR for 84 developing countries. Geographic Information System (GIS) software has been used to overlay the best available, spatially-disaggregated global data on critical impact elements (land, population, agriculture, urban extent, wetlands, and GDP) with the inundation zones projected for 1-5m SLR. The results reveal that hundreds of millions of people in the developing world are likely to be displaced by SLR within this century, and accompanying economic and ecological damage will be severe for many. At the country level, results are extremely skewed, with severe impacts limited to a relatively small number of countries. For these countries (such as Vietnam, A. R. of Egypt, and The Bahamas), however, the consequences of SLR are potentially catastrophic. For many others, including some of the largest (such as China), the absolute magnitudes of potential impacts are very large. At the other extreme, many developing countries experience limited impacts. Among regions, East Asia and the Middle East and North Africa exhibit the greatest relative impacts. To date, there is little evidence that the international community has seriously considered the implications of SLR for population location and infrastructure planning in developing countries. The authors hope that the information provided in this paper will encourage immediate planning for adaptation.Wetlands,Climate Change,Population Policies,Country Strategy&Performance,Geographical Information Systems

Revisiting the TALE repeat

Transcription activator-like (TAL) effectors specifically bind to double stranded (ds) DNA through a central domain of tandem repeats. Each TAL effector (TALE) repeat comprises 33–35 amino acids and recognizes one specific DNA base through a highly variable residue at a fixed position in the repeat. Structural studies have revealed the molecular basis of DNA recognition by TALE repeats. Examination of the overall structure reveals that the basic building block of TALE protein, namely a helical hairpin, is one-helix shifted from the previously defined TALE motif. Here we wish to suggest a structure-based re-demarcation of the TALE repeat which starts with the residues that bind to the DNA backbone phosphate and concludes with the base-recognition hyper-variable residue. This new numbering system is consistent with the α-solenoid superfamily to which TALE belongs, and reflects the structural integrity of TAL effectors. In addition, it confers integral number of TALE repeats that matches the number of bound DNA bases. We then present fifteen crystal structures of engineered dHax3 variants in complex with target DNA molecules, which elucidate the structural basis for the recognition of bases adenine (A) and guanine (G) by reported or uncharacterized TALE codes. Finally, we analyzed the sequence-structure correlation of the amino acid residues within a TALE repeat. The structural analyses reported here may advance the mechanistic understanding of TALE proteins and facilitate the design of TALEN with improved affinity and specificity. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s13238-014-0035-2) contains supplementary material, which is available to authorized users