Fundamental Study to Create a Joint Modeling Bringing up a Skill to Build a Relationship in a Childcare Facility

近年の社会変化により，子どもの遊びには変化が見られ，主体性を発揮して夢中になれる活動や，友達とやりとりをしながら創造性を発揮する機会が，必要とされている。つまり，遊びを通した子ども同士の関わりは，道徳性・社会性を育み，人間関係形成能力を育むための重要な課題であると指摘できる。人間関係形成能力を育むための活動の１つとして，共同造形制作が考えられる。本論では，子ども同士の関わりを作る造形表現活動の実践は，１人では作ることができない大きな作品で，アイデアを多く必要とする「寄せがき方式」の制作遊びを設定して行うことが望ましいと考えられる。創造的な遊びには，子どもにとって友達とイメージを共有して作る要素が多く，テーマや色や形を工夫していくことができると考える。Due to recent social changes, we can see changes in how children play and it is required to have activities that they can really into by exercising independence or opportunities in which they can exercise creativity by communicating with friends. Accordingly, we can indicate that communication among children through playing will be an important issue to grow morality and sociality as well as growing skills to build a relationship. As one of activities to grow skills to build a relationship, we can consider a joint modeling. In this study, we consider that practices of activities to express modeling that build a relationship among children should be a big work that cannot be created alone therefore it is desirable to proceed such practices by setting a play to create a “message method” that require a lot of ideas. Creative play has many elements created by sharing images with friends for children and we consider that they can devise themes, colors, and shapes

Data Delivery Method Based on Neighbor Nodes’ Information in a Mobile Ad Hoc Network

This paper proposes a data delivery method based on neighbor nodes’ information to achieve reliable communication in a mobile ad hoc network (MANET). In a MANET, it is difficult to deliver data reliably due to instabilities in network topology and wireless network condition which result from node movement. To overcome such unstable communication, opportunistic routing and network coding schemes have lately attracted considerable attention. Although an existing method that employs such schemes, MAC-independent opportunistic routing and encoding (MORE), Chachulski et al. (2007), improves the efficiency of data delivery in an unstable wireless mesh network, it does not address node movement. To efficiently deliver data in a MANET, the method proposed in this paper thus first employs the same opportunistic routing and network coding used in MORE and also uses the location information and transmission probabilities of neighbor nodes to adapt to changeable network topology and wireless network condition. The simulation experiments showed that the proposed method can achieve efficient data delivery with low network load when the movement speed is relatively slow

Sugoroku Play through Collaborative Molding Creation to Develop Skills to Establish Relationship among Children in 4-Year-Old Class of Nursery School

人間関係形成能力を育むための活動の１つとして，共同造形制作が考えられる。共同造形制作は，１人では作ることができない大きな作品で，着想を多く必要とする「寄せがき方式」の制作遊びを設定して行うことが望ましい。そこで，具体的な保育実践案として双六遊びを行い，人間関係形成能力育成における有効性の検証と，保育者に求められる指導・援助方法の考察を行った。双六の制作は，友達の発言や行動に関心を持ちやすい環境で行われ，話し合いによって色や形を工夫することができた。また，双六遊びの偶然性やルール作りの必要性から，発達過程に適合した楽しい遊びを通して友達と深く関われる活動であったと言える。保育者の援助においては，子どもが人間関係を形成する上で，イメージの共有を促す声掛けが必要であると共に，保育者が介入しない見守りも重要であった。We can consider that one of activities to develop skills to establish relationship is collaborative molding creation. Collaborative modeling creation is a large piece of work that cannot be created by a single person, and it is desirable to set up a "Yosegaki type" of creation play that requires a lot of inspiration. Accordingly, we conducted Sugoroku play as a detailed nursing practice idea to verify its effectiveness in developing skill to establish relationship and considered the teaching and support methods required of childcare-givers. Sugoroku was made in an environment where children were able to pay attention to what their friends said and did, and they were able to devise colors and shapes through discussion. Moreover, from the coincidental nature of Sugoroku play and the necessity of making rules, we could say that it was an activity to be deeply involved with friends through fun play adapted to the developmental process. In assisting childcare-givers, it was important to encourage children to share images and to watch them without intervention by childcare-givers in developing relationship among children

Concordance of acquired mutations between metastatic lesions and liquid biopsy in metastatic colorectal cancer

Aim: To evaluate whether PCR-reverse sequence-specific oligonucleotide can examine the concordance between liquid biopsy and metastatic lesions with acquired resistance. Materials & methods: We examined acquired mutations in chemoresistant lesions and blood obtained from four patients with RAS wildtype metastatic colorectal cancer who underwent treatment with anti-epidermal growth factor receptor antibodies. Results: In one patient, metastatic lesions harbored diverse acquired mutations in KRAS in all seven metastases; the two acquired mutations were detectable in blood collected after the patient acquired resistance. None of the other patients exhibited liquid biopsy mutations, except one, with a BRAF mutation confirmed in primary tumor and peritoneal dissemination. Conclusion: Liquid biopsy based on PCR-reverse sequence-specific oligonucleotide is a successful procedure for capturing acquired mutations with precise information on the RAS mutational spectrum