104 research outputs found

    IRD dropout study

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    This final report describes work performed by SRS Technologies for the NASA Marshall Space Flight Center under Contract NAS8-39077, entitled 'Integrated Receiver-Decoder Dropout Study'. The purpose of the study was to determine causes of signal fading effects on ultra-high-frequency (UHF) range safety transmissions to the Space Shuttle during flyout. Of particular interest were deep fades observed at the External Tank (ET) Integrated Receiver-Decoder (IRD) during the flyout interval between solid rocket booster separation and ET separation. Analytical and simulation methods were employed in this study to assess observations captured in flight telemetry data records. Conclusions based on the study are presented in this report, and recommendations are given for future experimental validation of the results

    COSEE OCEAN Inquiry Group Report: Opportunities for Creating Lifelong Ocean Science Literacy

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    This Inquiry Group Report for the Centers for Ocean Sciences Education Excellence Ocean Communities in Education And Social Networks (COSEE OCEAN) provides a fresh look at how broader ocean science literacy can be developed, especially through less-recognized channels such as opportunistic learning, the private and “third” sectors, and the enormously varied activities under the heading of informal science education. The 10 authors of this report (see Contributors section) have been working together for two years to find and review a range of issues and resources for current and potential ocean science literacy providers, both professional and volunteer. Several chapters provide a survey of useful materials and websites, while others offer ideas that will be new for many readers, including opportunities and unfamiliar venues for carrying out this enterprise. Included are chapters depicting a perhaps surprising plethora of channels for increasing ocean science literacy, both in school and especially, out of school. Other chapters discuss the societal contexts for using these channels, which include ideas for potential funding sources and cultural partners. Not every reader will find every chapter useful so each chapter is written to stand alone. This requires redundancy of some material from chapter to chapter. The primary authors for each chapter have their own writing styles and voice. Finally, given the varied topics of each chapter, some are dense with annotated lists of existing materials, while others were written to analyze fresh opportunities for the creation of new materials and projects. This report was written with several audiences in mind: the professional educators in the Centers for Ocean Sciences Education Excellence (COSEE) network; formal and informal educators who are looking for ways to incorporate ocean sciences in the work they do; and policymakers in both science and education who are concerned with using all available channels to improve the public understanding of such major concerns as global climate change, energy sources and uses, the health of local and global ecosystems, and natural resources such as seafood

    Analysis of visitors’ mobility patterns through random walk in the Louvre Museum

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    This paper proposes a random walk model to analyze visitors' mobility patterns in a large museum. Visitors' available time makes their visiting styles different, resulting in dissimilarity in the order and number of visited places and in path sequence length. We analyze all this by comparing a simulation model and observed data, which provide us the strength of the visitors' mobility patterns. The obtained results indicate that shorter stay-type visitors exhibit stronger patterns than those with the longer stay-type, confirming that the former are more selective than the latter in terms of their visitation type.Comment: 16 pages, 5 figures, 4 table

    Overexpression of Inosine 5′-Monophosphate Dehydrogenase Type II Mediates Chemoresistance to Human Osteosarcoma Cells

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    overexpression in osteosarcoma patients with poor response to chemotherapy. The aim of this study was to provide evidence for direct involvement of IMPDH2 in the development of chemoresistance..IMPDH2 is directly involved in the development of chemoresistance in osteosarcoma cells, suggesting that targeting of IMPDH2 by RNAi or more effective pharmacological inhibitors in combination with chemotherapy might be a promising means of overcoming chemoresistance in osteosarcomas with high IMPDH2 expression
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