30 research outputs found
LAMP: a micro-satellite based soft X-ray polarimeter for astrophysics
The Lightweight Asymmetry and Magnetism Probe (LAMP) is a micro-satellite
mission concept dedicated for astronomical X-ray polarimetry and is currently
under early phase study. It consists of segmented paraboloidal multilayer
mirrors with a collecting area of about 1300 cm^2 to reflect and focus 250 eV
X-rays, which will be detected by position sensitive detectors at the focal
plane. The primary targets of LAMP include the thermal emission from the
surface of pulsars and synchrotron emission produced by relativistic jets in
blazars. With the expected sensitivity, it will allow us to detect polarization
or place a tight upper limit for about 10 pulsars and 20 blazars. In addition
to measuring magnetic structures in these objects, LAMP will also enable us to
discover bare quark stars if they exist, whose thermal emission is expected to
be zero polarized, while the thermal emission from neutron stars is believed to
be highly polarized due to plasma polarization and the quantum electrodynamics
(QED) effect. Here we present an overview of the mission concept, its science
objectives and simulated observational results
Comparative Genomics Study of Multi-Drug-Resistance Mechanisms in the Antibiotic-Resistant Streptococcus suis R61 Strain
BACKGROUND: Streptococcus suis infections are a serious problem for both humans and pigs worldwide. The emergence and increasing prevalence of antibiotic-resistant S. suis strains pose significant clinical and societal challenges. RESULTS: In our study, we sequenced one multi-drug-resistant S. suis strain, R61, and one S. suis strain, A7, which is fully sensitive to all tested antibiotics. Comparative genomic analysis revealed that the R61 strain is phylogenetically distinct from other S. suis strains, and the genome of R61 exhibits extreme levels of evolutionary plasticity with high levels of gene gain and loss. Our results indicate that the multi-drug-resistant strain R61 has evolved three main categories of resistance. CONCLUSIONS: Comparative genomic analysis of S. suis strains with diverse drug-resistant phenotypes provided evidence that horizontal gene transfer is an important evolutionary force in shaping the genome of multi-drug-resistant strain R61. In this study, we discovered novel and previously unexamined mutations that are strong candidates for conferring drug resistance. We believe that these mutations will provide crucial clues for designing new drugs against this pathogen. In addition, our work provides a clear demonstration that the use of drugs has driven the emergence of the multi-drug-resistant strain R61
Combined use of probucol and cilostazol with atorvastatin attenuates atherosclerosis in moderately hypercholesterolemic rabbits
Research Article Several Existence Theorems of Nonlinear m-Point BVP for an Increasing Homeomorphism and Homomorphism on Time Scales
Several existence theorems of positive solutions are established for nonlinear m-point boundary value problem for the following dynamic equations on time scales �φ�uΔ� � ∇ � a�t�f�t, u�t� � � 0, t ∈ �0,T�, φ�uΔ�0� � � ∑m−2 i�1 aiφ�uΔ�ξi��, u�T � � ∑m−2 i�1 biu�ξi�, where φ: R→R is an increasing homeomorphism and homomorphism and φ�0 � �0. As an application, an example to demonstrate our results is given. Copyright q 2008 Yanbin Sang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 1
Finite/Fixed-Time Stabilization for Nonlinear Interconnected Systems With Dead-Zone Input
A Hybrid of NARX and Moving Average Structures for Exhaust Gas Temperature Prediction of Gas Turbine Engines
Aiming at engine health management, a novel hybrid prediction method is proposed for exhaust gas temperature (EGT) prediction of gas turbine engines. This hybrid model combines a nonlinear autoregressive with exogenous input (NARX) model and a moving average (MA) model. A feature attention mechanism-enhanced long short-term memory network (FAE-LSTM) is first developed to construct the NARX model, which is used for identifying the aircraft engine using condition parameters and gas path measurement parameters that correlate to the EGT. A vanilla LSTM is then used for constructing the MA model, which is used for improving the difference between the actual EGT and the predicted EGT given by the NARX model. The proposed method is evaluated using real flight process data and compared to several dynamic prediction techniques. The results show that our hybrid model reduces the predicted RMSE and MAE by at least 13.23% and 18.47%, respectively. The developed FAE-LSTM network can effectively deal with dynamic data. Overall, the present work demonstrates a promising performance and provides a positive guide for predicting engine parameters
Erosion and covered zones altered by surface coverage effects on soil nitrogen and carbon loss from an agricultural slope under laboratory-simulated rainfall events
Soil erosion, one of the most serious environmental concerns, might remove topsoil and essential element from terrestrial land. However, few attentions have been given to investigating how soil erosion regimes affect soil carbon and nitrogen loss. Therefore, this study investigated the effects of surface coverage rates (83%, 67%, 50%, 33%, 17% and 0%) and two positions (up- and downslope) on erosion regimes and its associated soil nitrogen and carbon loss under a sequence of six rainfalls (R1-R6). These results showed that the sediment concentrations with 33% (R4) and 17% (R5) coverage downslope were significantly lower than those with coverage upslope, whereas there was no significant difference between the runoff rates of the two slopes. Thus, surface coverage at different positions induced two soil erosion regimes (deposition- and transport-dominated processes). Dynamics of the DON and DIN concentrations indicated different release processes of soil nitrogen into runoff. The DON contributed to a substantial amount of soil nitrogen loss, which accounted approximately 81% of the organic form. The SBOC is significantly correlated with sediment-enriched clay particles from the deposition-dominated processes and is higher than that from the transport-dominated processes. The DOC is significantly correlated with Rr for transport-dominated processes. These results illustrated the critical role of erosion regimes in soil organic carbon loss in dissolved or sediment-bound form. It is concluded that erosion/covered zones altered by surface coverage could produce transport- and deposition-dominated erosion regimes and consequently affect soil carbon and nitrogen loss. In addition, these results demonstrated that surface coverage pattern may efficiently control soil erosion and soil carbon and nitrogen loss
Mechanical Analysis of Frictional Continuous Cable Systems Considering the Influence of Load Path
Continuous cables are widespread in various fields, and mechanical analysis is an important issue in their application. The structural responses of frictional continuous cable systems under external loads are related to the load path. The influence of load path has seldom been considered in the existing analysis methods. This paper proposes a novel approach for the mechanical analysis of continuous cable systems considering the influence of load path. The constitutive relation of the frictional continuous cables was derived, in which the sliding amount parameters were eliminated. The computational frameworks for both definite and indefinite load path cases were proposed. For a definite load path, the structural responses can be uniquely determined by successively trials and modifications of the nodal sliding state. For an indefinite load path, a formula of all the possible structural responses was derived, and the ranges of the structural responses can be obtained. All computations in the approach were converted to matrix operations. The effectiveness and practicability of the proposed approach were demonstrated by two typical numerical examples