Maximizing Friend-Making Likelihood for Social Activity Organization

The social presence theory in social psychology suggests that computer-mediated online interactions are inferior to face-to-face, in-person interactions. In this paper, we consider the scenarios of organizing in person friend-making social activities via online social networks (OSNs) and formulate a new research problem, namely, Hop-bounded Maximum Group Friending (HMGF), by modeling both existing friendships and the likelihood of new friend making. To find a set of attendees for socialization activities, HMGF is unique and challenging due to the interplay of the group size, the constraint on existing friendships and the objective function on the likelihood of friend making. We prove that HMGF is NP-Hard, and no approximation algorithm exists unless P = NP. We then propose an error-bounded approximation algorithm to efficiently obtain the solutions very close to the optimal solutions. We conduct a user study to validate our problem formulation and per- form extensive experiments on real datasets to demonstrate the efficiency and effectiveness of our proposed algorithm

Optimization of Enzymatic Hydrolysis and Decolorization Process of Walnut Protein

This paper aimed at the high-value utilization of walnut cake, a by-product of oil processing industry. The walnut protein (WP) was extracted by alkali extraction-acid precipitation method from cold-pressed walnut cake, then trypsin hydrolysis process was optimized by single factor experiment and orthogonal design, with degree of hydrolysis (DH) as the indicator. Subsequently, the decolorization process of WP hydrolysate was optimized with protein recovery rate and decolorization rate as the indicators. The results showed that the extracted walnut protein was of high purity and could be used for further enzymatic hydrolysis and decolorization tests. After optimization, the DH of WP could be increased to 21.08% under the following conditions: the substrate concentration of 3%, the hydrolysis temperature of 55 ℃, the enzyme addition of 6 250 U/g protein, and the enzymatic hydrolysis time of 5 h. The optimal process of decolorization of walnut protease hydrolysate was obtained at an activated carbon addition of 1.2% (W/V), a pH of 4.5, a adsorption temperature of 45 ℃, and a decolorization time of 90 min. Under these conditions, the decolorization rate of walnut protease hydrolysate was 78.05%, protein recovery rate was 82.16%, and the combined weighted mean score was 80.11. The optimization process of trypsin hydrolysis and decolorization could provide some references for the development and utilization of walnut cake

Drug-induced hypersensitivity syndrome related to piperacillin-tazobactam: a case report and review of the literature

Allergic reactions to drugs caused by piperacillin-tazobactam are common in clinical practice. However, we also found a few cases of drug-induced hypersensitivity syndrome (DiHS)/Drug reaction with eosinophilia and systemic symptoms (DRESS) caused by piperacillin-tazobactam in our clinical work. We report a case of a 60-year-old female patient who was treated with piperacillin-tazobactam anti-infective therapy after the diagnosis of hematogenous lung abscess, developed fever, rash, and blood abnormalities after 26 days of application, and was later diagnosed as DIHS, which was improved after the administration of glucocorticoid and anti-allergic drugs. In addition, we also retrospectively analyzed 17 cases of DiHS caused by piperacillin-tazobactam from the PubMed databases between March 1980 and September 2023. The majority of the patients had an incubation period of more than 14 days, and the common clinical features included elevated eosinophil count/percentage, fever, rash, liver damage, and lymph node enlargement. After treatment with topical or systemic glucocorticoids, 16 of the 17 patients improved and one died because of the underlying condition. The clinical features of DiHS were diverse and included a long incubation period, skin rash, elevated eosinophils, and impaired organ function. Since some patients have atypical clinical features, clinicians should raise awareness of the disease, recognize these features early, and treat them promptly

The Effects of the interfacial Pseudo-spin Coupling Fluctuation on the Dielectric Property of a Ferroelectric Superlattice

Using effective-field theory with correlations, we investigate the effects of interfacial pseudo-spin coupling fluctuations on the susceptibility and polarization of ferroelectric superlattices within the framework of transverse Ising model. It is found that the interfacial coupling fluctuations increase the susceptibility in the low temperature region. For a strong interfacial coupling, the phase transition temperature decreases with the strength of fluctuations of the interfacial coupling. The dependence of the susceptibility on the superlattice period of $BaTiO_{3}/SrTiO_{3}$ are plotted for different interfacial coupling fluctuations strength. At room temperature, when the interfacial coupling fluctuation increases, the peak position of the susceptibility will shift to a large superlattice period.Comment: 14 pages, 5 figures, RevTex

Association Between Vitamin D Receptor Gene Polymorphisms and Polycystic Ovary Syndrome Risk: A Meta-Analysis

Objective: Published studies have demonstrated a closer association between vitamin D receptor (VDR) gene polymorphisms and polycystic ovary syndrome (PCOS) risk, but the results were inconsistent. We therefore performed this meta-analysis to explore the precise associations between VDR gene polymorphisms and PCOS risk.Methods: Five online electronic databases (PubMed, Embase, SCI index, CNKI and Wanfang) were searched. Odds ratios (ORs) with 95% confidence interval (CIs) were calculated to assess the association between VDR Fok I C/T (rs10735810), BsmI A/G (rs1544410), ApaI A/C (rs7975232), and TaqI T/C (rs731236) polymorphisms and PCOS risk. In addition, heterogeneity, accumulative/sensitivity analysis and publication bias were conducted to check the statistical power.Results: Overall, 10 publications (31 independent case-control studies) involving 1,531 patients and 1,174 controls were identified. We found that the C mutation of ApaI A/C was a risk factor for PCOS (C vs. A: OR = 1.20, 95%CI = 1.06–1.35, P < 0.01, I2 = 29.7%; CC vs. AA: OR = 1.49, 95%CI = 1.17–1.91, P < 0.01, I2 = 0%; CC vs. AA+AC: OR = 1.36, 95%CI = 1.09–1.69, P = 0.01, I2 = 12.8%). Moreover, the BsmI A/G polymorphism also showed a dangerous risk for PCOS in Asian population (G vs. A: OR = 1.62, 95%CI = 1.24–2.11, P < 0.01, I2 = 0%; AG vs. AA: OR = 2.08, 95%CI = 1.26–3.20, P < 0.01, I2 = 0%; GG vs. AA: OR = 2.21, 95%CI = 1.29–3.77, P < 0.01, I2 = 0%; AG+GG vs. AA: OR = 2.12, 95%CI = 1.42–3.16, P < 0.01, I2 = 0%). In addition, no significant association of Fok I C/T, and TaqI T/C polymorphisms was observed.Conclusions: In summary, our meta-analysis suggested that VDR gene polymorphisms contribute to PCOS development, especially in Asian populations