Neutrino Mixing Predictions of a Minimal SO(10) Model with Suppressed Proton Decay

During the past year, a minimal renormalizable supersymmetric SO(10) model has been proposed with the following properties: it predicts a naturally stable dark matter and neutrino mixing angles theta_atm and theta_13 while at the same time accommodating CKM CP violation among quarks with no SUSY CP problem. Suppression of proton decay for all allowed values of tan beta strongly restricts the flavor structure of the model making it predictive for other processes as well. We discuss the following predictions of the model in this paper, e.g. down-type quark masses, and neutrino oscillation parameters, U_e3, delta_MNSP, which will be tested by long baseline experiments such as T2K and subsequent experiments using the neutrino beam from JPARC. We also calculate lepton flavor violation and the lepton asymmetry of the Universe in this model.Comment: 22 pages, 11 figure

Kraus representation in the presence of initial correlations

We examine the validity of the Kraus representation in the presence of initial correlations and show that it is assured only when a joint dynamics is locally unitary.Comment: REVTeX4, 12 page

Confidence and Backaction in the Quantum Filter Equation

We study the confidence and backaction of state reconstruction based on a continuous weak measurement and the quantum filter equation. As a physical example we use the traditional model of a double quantum dot being continuously monitored by a quantum point contact. We examine the confidence of the estimate of a state constructed from the measurement record, and the effect of backaction of that measurement on that state. Finally, in the case of general measurements we show that using the relative entropy as a measure of confidence allows us to define the lower bound on the confidence as a type of quantum discord.Comment: 9 pages, 6 figure

An improved single-cell cDNA amplification method for efficient high-density oligonucleotide microarray analysis

A systems-level understanding of a small but essential population of cells in development or adulthood (e.g. somatic stem cells) requires accurate quantitative monitoring of genome-wide gene expression, ideally from single cells. We report here a strategy to globally amplify mRNAs from single cells for highly quantitative high-density oligonucleotide microarray analysis that combines a small number of directional PCR cycles with subsequent linear amplification. Using this strategy, both the representation of gene expression profiles and reproducibility between individual experiments are unambiguously improved from the original method, along with high coverage and accuracy. The immediate application of this method to single cells in the undifferentiated inner cell masses of mouse blastocysts at embryonic day (E) 3.5 revealed the presence of two populations of cells, one with primitive endoderm (PE) expression and the other with pluripotent epiblast-like gene expression. The genes expressed differentially between these two populations were well preserved in morphologically differentiated PE and epiblast in the embryos one day later (E4.5), demonstrating that the method successfully detects subtle but essential differences in gene expression at the single-cell level among seemingly homogeneous cell populations. This study provides a strategy to analyze biophysical events in medicine as well as in neural, stem cell and developmental biology, where small numbers of distinctive or diseased cells play critical roles

CANGAROO-III Search for Gamma Rays from SN 1987A and the Surrounding Field

Optical images of SN 1987A show a triple ring structure. The inner (dust) ring has recently increased in brightness and in the number of hot spots suggesting that the supernova shock wave has collided with the dense pre-existing circumstellar medium, a scenario supported by radio and X-ray observations. Such a shocked environment is widely expected to result in the acceleration of charged particles, and the accompanying emission of very high energy gamma-rays. Here, we report the results of observations made in 2004 and 2006 which yield upper limits on the TeV gamma-ray flux, which are compared with a theoretical prediction. In addition, we set upper limits on the TeV flux for four high energy objects which are located within the same field of view of the observation: the super-bubble 30 Dor C, the Crab-like pulsar PSR B0540$-$69, the X-ray binary LMC X-1, and the supernova remnant N157B.Comment: 5 pages, 5 figures, Accepted for publication in Ap

Large Angle MSW Solution in Grand Unified Theories with SU(3) X U(1) Horizontal Symmetry

We construct a model with a SU(3) X U(1) horizontal symmetry in the context of Grand Unified Theories. In our models, the bi-maximal lepton mixing and suitable neutrino masses for the large angle MSW solution are obtained without any fine-tuning due to the spontaneously broken SU(3)_H symmetry. The three generations of quarks and leptons are unified as members of the SU(3)_H fundamental representation, and the U(1)_H charge gives the origin of the fermion mass hierarchy and mixing angles. We present two explicit examples of SU(5)_GUT and SO(10)_GUT models, in which the Yukawa structures are given successfully.Comment: 23 pages, 6 figures, references adde

Focus on high energy particles and atmospheric processes

The letters published in the ‘Focus issue on high energy particles and atmospheric processes’ serve to broaden the discussion about the influence of high energy particles on the atmosphere beyond their possible effects on clouds and climate. These letters link climate and meteorological processes with atmospheric electricity, atmospheric chemistry, high energy physics and aerosol science from the smallest molecular cluster ions through to liquid droplets. Progress in such a disparate and complex topic is very likely to benefit from continued interdisciplinary interactions between traditionally distinct science areas

The Sliding Singlet Mechanism with Gauge Mediated Supersymmetry Breaking

The sliding singlet mechanism is one of the most interesting solutions of the triplet-doublet splitting problem. We analyze this mechanism in the gauge mediated supersymmetry breaking scenario. We show that the sliding singlet mechanism does not work in the naive gauge mediation scenario because of the singlet linear terms derived from the gravity, although $F$ term is much smaller than the one in the gravity mediation scenario. We also consider the extension in order for the sliding singlet mechanism to work.Comment: LaTeX 15 pages, no figures, mistakes in Eq.(3.27) crrected, a part of conclusion correcte

Model Building with Gauge-Yukawa Unification

In supersymmetric theories with extra dimensions, the Higgs and matter fields can be part of the gauge multiplet, so that the Yukawa interactions can arise from the gauge interactions. This leads to the possibility of gauge-Yukawa coupling unification, g_i=y_f, in the effective four dimensional theory after the initial gauge symmetry and the supersymmetry are broken upon orbifold compactification. We consider gauge-Yukawa unified models based on a variety of four dimensional symmetries, including SO(10), SU(5), Pati-Salam symmetry, trinification, and the Standard Model. Only in the case of Pati-Salam and the Standard Model symmetry, we do obtain gauge-Yukawa unification. Partial gauge-Yukawa unification is also briefly discussed.Comment: 23 page

The Influence of Multilevel Spinal Deformity Surgery on the EuroQol 5 Dimensions' (EQ-5D) Questionnaire and Residential Status in the Elderly: A Prospective, Observational, Multicenter Study

STUDY DESIGN: Multicenter, international prospective study. OBJECTIVE: This study investigated the clinical outcome up to 2 years after multi-level spinal deformity surgery in the elderly by reporting the minimal clinically important difference (MCID) of EuroQol 5-dimensions (EQ-5D), EQ-VAS, and residential status. METHODS: As an ancillary study of 219 patients ≥60 years with spinal deformity undergoing primary instrumented fusion surgery of ≥5 levels, this study focuses on EQ-5D (3-L) as the primary outcome and EQ-VAS and residential status as secondary outcomes. Data on EQ-5D were compared between pre-operatively and postoperatively at 10 weeks, 12 months, and 24 months. An anchor-based approach was used to calculate the MCID. RESULTS: The EQ-5D index and EQ-VAS, respectively, improved significantly at each time point compared to pre-operatively (from .53 (SD .21) and 55.6 (SD 23.0) pre-operatively to .64 (SD .18) and 65.8 (SD 18.7) at 10 weeks, .74 (SD .18) and 72.7 (SD 18.1) at 12 months, and .73 (SD .20) and 70.4 (SD 20.4) at 24 months). 217 (99.1%) patients lived at home pre-operatively, while 186 (88.6%), 184 (98.4%), and 172 (100%) did so at 10 weeks, 12 months, and 24 months, respectively. Our calculated MCID for the EQ-5D index at 1 year was .22 (95% CI .15-.29). CONCLUSIONS: The EQ-5D index significantly increased at each time point over 24 months after ≥5 level spinal deformity surgery in elderly patients. The MCID of the EQ-5D-3 L was .22. Patients living at home pre-operatively can expect to be able to live at home 2 years postoperatively