72 research outputs found
Piezoelectric material selection for transducers under fuzzy environment
- Author
- A Chauhan
- A Chauhan
- A Chauhan
- A Shemshadi
- B Dehgan-Manshadi
- CW Ahn
- D Damjanovic
- D Schofield
- DM Lin
- DQ Xiao
- E Hollenstein
- GH Haertling
- GH Haertling
- GZ Zang
- H Deng
- H Jaffe
- H Jaffe
- J Rödel
- JF Tressler
- K Devi
- L Egerton
- MK Zhu
- MS Kuo
- NM Hagh
- NM Hagh
- O Elkechai
- P Chatterjee
- P Sen
- R Vaish
- RE Jaeger
- RJ Girubha
- RV Rao
- RZ Zuo
- S Opricovic
- S Opricovic
- SE Park
- ST Lau
- T Kaya
- TL Saaty
- TR Shrout
- W Chen
- Y Guo
- Y Saito
- Y Saito
- Y Yuan
- YP Guo
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
- Author
- Abdel-Aziz AK
- Abdelfatah S
- Abdellatif M
- Abdoli A
- Abel S
- Abeliovich H
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- Ahmad ST
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- Varano G
- Varela-Nieto I
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- Vasconcelos MH
- Vats S
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- Vega-Naredo I
- Vega-Rubin-de-Celis S
- Velasco G
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- Vidoni C
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- ViganĂł S
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- Villalba JM
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- Vocadlo DJ
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- Vucicevic L
- Wade-Martins R
- Waguri S
- Waite KA
- Wakatsuki S
- Walker DW
- Walker MJ
- Walker SA
- Walter J
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- Wang Q
- Wang QA
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- Wang QK
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- WawrzyĆska A
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- Wehman AM
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- WeiergrÀber OH
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- Weindl G
- Weiskirchen R
- Wells A
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- Werner A
- Weykopf B
- Wheatley SP
- Whitton JL
- Whitworth AJ
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- Wildenberg ME
- Wileman T
- Wilkinson S
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- Williams RSB
- Williamson PR
- Wilson RA
- Winner B
- Winsor NJ
- Witkin SS
- Wodrich H
- Woehlbier U
- Wollert T
- Wong E
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- Wong RW
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- Wu A-G
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- Wu KK
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- Wu S-Y
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- Wu WKK
- Wu X
- Wu X
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- Wu Y-W
- Xavier RJ
- Xia H
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- Xiang G
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- Xiao H-T
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- Xue Y
- Yakhine-Diop SMS
- Yamaguchi M
- Yamaguchi O
- Yamamoto A
- Yamashina S
- Yan S
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- Yanagi Y
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- Yang D-S
- Yang H
- Yang H
- Yang H-T
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- Yang P-M
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- Yang S-F
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- Yang WY
- Yang X
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- Yao S
- Yao X
- Yao Y-G
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- Yasui T
- Yazdankhah M
- Yen PM
- Yi C
- Yi-Ren Hong C-WH
- Yin X-M
- Yin Y
- Yin Z
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- Ying M
- Ying Z
- Yip CK
- Yiu SPT
- Yoo YH
- Yoshida K
- Yoshii SR
- Yoshimori T
- Yousefi B
- Yu B
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- Yu M-L
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- Yun J
- Yung RL
- Zacks DN
- Zaffagnini G
- Zambelli VO
- Zanella I
- Zang QS
- Zanivan S
- Zappavigna S
- Zaragoza P
- Zarbalis KS
- Zarebkohan A
- Zarrouk A
- Zeitlin SO
- Zeng J
- Zeng J-D
- Zhan L
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- Zhang KYB
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- Zhang X-W
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- Zhang Y-D
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- Zheng G
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- Zheng S
- Zheng X-L
- Zheng Y
- Zheng Z-G
- Zhivotovsky B
- Zhong Q
- Zhou A
- Zhou B
- Zhou C
- Zhou G
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- Zhou J
- Zhou J
- Zhou J
- Zhou K
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- Zhou X-J
- Zhou Y
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- Zhou Y
- Zhou Z
- Zhou Z-Y
- Zhu B
- Zhu C
- Zhu G-Q
- Zhu H
- Zhu H
- Zhu H
- Zhu W-G
- Zhu Y
- Zhu Y
- Zhuang H
- Zhuang X
- Zientara-Rytter K
- Zimmermann CM
- Ziviani E
- Zoladek T
- Zong W-X
- Zorov DB
- Zorzano A
- Zou W
- Zou Z
- Zou Z
- Zuryn S
- Zwerschke W
- Ălvarez ĂMC
- Ăvalos Y
- Ănal G
- ĂstĂŒn S
- ÄoliÄ M
- ÄokiÄ J
- Ćœerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
Efficacy of Major Plant Extracts/Molecules on Field Insect Pests
- Author
- A Bermejo
- A Bozsik
- A Cavé
- A Guadaño
- A Krishnamurthi
- A Kumar
- A Mondal
- A Prakash
- A Valencia
- AD Solsoloy
- AD Solsoloy
- AI Rocha Da
- AJ Mordue
- AJ Mordue
- AK Tripathi
- AP Jarvis
- AP Jarvis
- AP Jarvis
- AV Reddy
- AW Richard
- B Meera
- B Murray
- B Ratnakumari
- B Rojano
- B Talopatra
- B Venkateswarlu
- BS Chandel
- BS Parmar
- C Thebtaranonth
- CM Boursier
- CM Priestley
- CW Sabandar
- D Chauhan
- D Ocampo
- D Prijono
- D Roy
- D Singh
- D Singh
- DA AdabieâGomez
- DAH Taylor
- DM Secoy
- DR Schroeder
- DS Alves
- EE Enan
- EJ Carcache-Blanco
- EL Scudeler
- EO Okonkwo
- ES Atawodi
- F Hasan
- FO Alao
- FQ Alali
- FQ Alali
- FR Chang
- G Ahmad
- G Goel
- G Parra-Henao
- G Schmahl
- G Shi
- GA Cordell
- GE Shi
- GE Veitch
- GF Antonious
- GK Bunker
- GM Liang
- GN Silva
- GP Garg
- H Rembold
- H Rembold
- H Rembold
- H Schmutterer
- H Schmutterer
- H Schmutterer
- H Schmutterer
- H Yin
- HA Johnson
- HAF Shafie El
- HB Broughton
- HI Katoune
- HM Kotkar
- HPS Makkar
- HPS Makkar
- HPS Makkar
- I Gelbic
- J Fontana
- J Kumar
- J Leatemia
- J Paul
- J Pereira
- JB Stokes
- JD Warthen
- JH Butterworth
- JH Butterworth
- JK Rupprecht
- JR Tormo
- K Biswas
- K Ermel
- K He
- K Simin
- K SlĂĄma
- KB Jadhau
- KC Chitra
- KD Rakshit
- KI Ahammadsahib
- KK Mohanty
- KMS Sundaram
- KMS Sundaram
- KMS Sundaram
- KMS Sundaram
- KO Adebowale
- L Jing
- L Lal
- L Li
- L Mengual
- L Zeng
- LE Castillo
- LP Ribeiro
- LW Chatrou
- M Bobadilla
- M Feldhege
- M Khalequzzaman
- M Khalequzzaman
- M Kumar
- M Leboeuf
- M Mazid
- M Rajguru
- M Sauerwein
- M Shrinivas
- MA Barnby
- MB Isman
- MB Isman
- MB Isman
- MB Isman
- MF Maia
- ML Pappas
- MN Acda
- MO Nwosu
- MY RĂos
- N Ahmad
- N Dhandapani
- N Khumrungsee
- National Research Council (NRC)
- NV Brinji
- NVS Rao
- O Koul
- O Koul
- O Koul
- O Onunkun
- O Ălvarez
- O Ălvarez
- OA CĂłlom
- OA CĂłlom
- OP Sidhu
- OP Sidhu
- P Cabone
- P Robledo-Reyes
- PP Yadav
- PR Sharma
- Premchand
- PV Pawar
- PWC Green
- R Pavela
- R Pavela
- R Pavela
- R PĂ©rez-Pacheco
- R Singh
- RB Yamasaki
- RB Yamasaki
- RC Seffrin
- RE Unicini Manganelli
- RJ Aerts
- RK Devappa
- RK Devappa
- RK Devappa
- RK Lindquist
- RS Susarla
- S Alam
- S Gopalakrishnan
- S Irulandi
- S Johnson
- S Mahey
- S Parvin
- S Pineda
- S Shameel
- S Shukla
- S Yule
- SB Malik
- SD Jolad
- SD Katekhaye
- SK Pavanaram
- SM Packiam
- SR Reena
- SS Martinez
- SS Nathan
- SS Nathan
- SS Nathan
- SS Shelke
- SS Shelke
- SV Ley
- T Colman-Saizarbitoria
- TR Govindachari
- V Bullangpoti
- V Kumar
- V Ravindra
- V Rozman
- V Sathyaseelan
- V Sharma
- V Sharma
- W Adolf
- W Haas
- W Kraus
- WB Akanbi
- WM Blaney
- XP Fang
- YP Singh
- ZA Habou
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
Insect pests are considered the major hurdle in enhancing the production and productivity of any farming system. The use of conventional synthetic pesticides has led to the emergence of pesticide-resistant insects, environmental pollution, and negative effects on natural enemies, which have caused an ecological imbalance of the predator-prey ratio and human health hazards; therefore, eco-friendly alternative strategies are required. The plant kingdom, a rich repertoire of secondary metabolites, can be tapped as an alternative for insect pest management strategies. A number of plants have been documented to have insecticidal properties against various orders of insects in vitro by acting as antifeedants, repellents, sterilant and oviposition deterrents, etc. However, only a few plant compounds are applicable at the field level or presently commercialised. Here, we have provided an overview of the broad-spectrum insecticidal activity of plant compounds from neem, Annona, Pongamia, and Jatropha. Additionally, the impact of medicinal plants, herbs, spices, and essential oils has been reviewed briefl
Stroke genetics informs drug discovery and risk prediction across ancestries
- Author
- Aamodt AH
- Abedi Vida
- Adams Hieab
- Adebajo OJ
- Adeoye AM
- Afzal S
- Ago Tetsuro
- Agunloye A
- Akinyemi J
- Akinyemi Rufus
- Akpa O
- Akpalu A
- Almgren P
- Alvarez-Sabin J
- Amin N
- Amouyel Philippe
- Anderson CD
- Anderson Christopher D.
- Aparicio HJ
- Arenillas JF
- Armasu SM
- Armstrong Nicole D.
- Arnett DK
- Arulogun O
- Attia J
- Ay H
- Bae Hee-Joon
- Bakker Mark K.
- Bammler TK
- Bartz Traci M.
- Bastarache Lisa
- Beiser AS
- Bell S
- Benavente OR
- Benn M
- Bennett David A.
- Berr C
- Bevan S
- Bis JC
- Bis Joshua C.
- Blay N
- Boerwinkle E
- Boncoraglio GB
- Bordes Constance
- Braekkan SK
- Brody JA
- Brouwers PJAM
- Brown RD
- Brumpton BM
- Buring JE
- Bustamante M
- Butterworth AS
- BĂžrte Sigrid
- Cain Anael
- Campos F
- Camps-Renom P
- Caro Ilana
- Carrera C
- Carty CL
- Caso V
- Castillo J
- Chasman Daniel I.
- Chauhan Ganesh
- Chen JS
- Chen MH
- Chen Pei-Hsin
- Chen WM
- Chen YP
- Chen Zhengming
- Cheng YC
- Cho Kelly
- Choi SH
- Chong Michael R.
- Chowhan A
- Christensen Kaare
- Clarke R
- Cole John W.
- Collins R
- Correa A
- Cotlarciuc I
- Cruchaga Carlos
- Cullell N
- Curtze S
- Cushman M
- CĂĄrcel-MĂĄrquez Jara
- Damrauer Scott M.
- Danesh J
- Dartigues JF
- de Andrade M
- de Bakker PIW
- de Cid R
- de Cid Rafael
- de Jager Phil L.
- de Jager PL
- de Kort PL
- de Laat KF
- de Leeuw FE
- de Leeuw Frank-Erik
- Debette Stephanie
- Delavaran H
- Deleuze JF
- Delgado P
- Delgado-Mederos R
- den Heijer T
- den Hoed M
- DeStefano AL
- Dhar R
- Diaz-Navarro R
- Dichgans Martin
- Dorr M
- Duan Q
- Ellekjaer H
- Endres Matthias
- Engelter ST
- Engstrom G
- Esko T
- Evans MK
- Fairhurst-Hunter Z
- Fakunle AG
- Falcone GJ
- FernĂĄndez-Cadenas Israel
- Ferreira LE
- Ferreira Leslie E.
- Fongang B
- Ford I
- Fornage Myriam
- Frantz S
- França Paulo H. C.
- Frazer KA
- Freijo M
- Frikke-Schmidt Ruth
- Fritsche LG
- Furie KL
- Gabrielsen ME
- Gallego-Fabrega C
- Gasca Natalie C.
- Gasca NC
- Geerlings MI
- Geerlings Mirjam I.
- Georgakis Marios K.
- Germain M
- Ghanbari M
- Gieger Christian
- Giese AK
- Giulianini F
- Gons RAR
- Gordon W
- Gottesman RF
- Grabe Hans J.
- Gravel S
- Gretarsdottir S
- Grewal RP
- Gudnason V
- Gudnason Vilmundur
- Guo Y
- Gurpreet WS
- Gustafsson S
- Habib Naomi
- Hachiya Tsuyoshi
- Haessler J
- Haeusler Karl Georg
- Hagen K
- Hamsten A
- Hansen JB
- Harris TB
- Hassan A
- Hata Jun
- Havulinna Aki S.
- He Jing
- He Yunye
- Heath AK
- Heath Alicia K.
- Heckbert SR
- Heit JA
- Heitsch L
- Heuch I
- Heuschmann Peter Ulrich
- Hill M
- Ho Yuk-Lam
- Holliday EG
- Hopewell Jemma C.
- Howard G
- Howson Joanna M. M.
- Hozawa A
- Hsu FC
- Huffman Jennifer E.
- Hveem K
- Hyacinth Hyacinth I.
- Ibanez L
- Ibrahim M
- Ikram MK
- Ikram Mohammad A.
- Ilinca A
- Ingelsson E
- Ingelsson M
- Inouye Michael
- Irvin Marguerite R.
- Irvin MR
- Iwasaki M
- Jackson RD
- Jacob Mina A.
- Jee Yon Ho
- Jenkins C
- Jensen GB
- Jeon Christina E.
- Jern Christina
- Jian XQ
- Jimenez-Conde J
- Johnson AD
- Johnson JA
- Jood K
- Jousilahti P
- Judy Renae L.
- Jukema J. Wouter
- Jung Keum J.
- JĂŒrgenson Tuuli
- Kabrhel C
- Kaffashian S
- Kalra L
- Kamanu Frederick K.
- Kamatani Yoichiro
- Kamouchi Masahiro
- Kamstrup PR
- Kanai M
- Kappelle LJ
- Keene Keith L.
- Kim BJ
- Kim J
- Kim Young Jin
- Kinnunen J
- Kissela BM
- Kitazono Takanari
- Kittner Steven J.
- Kjartansson O
- Kleindorfer DO
- Kleinschnitz C
- Kloss M
- Knol Maria J.
- Koido Masaru
- Komolafe M
- Konuma Takahiro
- Kooperberg C
- Koudstaal PJ
- Kraft P
- Krebs Kristi
- Kristoffersen ES
- Krupinski J
- Kubo M
- Kumar Amit
- KÔrv Janika
- Labovitz DL
- Lacaze Paul
- Lange LA
- Langefeld CD
- Langenberg C
- Lathrop G. Mark
- Launer Lenore J.
- Laurie CC
- Le Grand Q
- Le Grand Quentin
- Lee JM
- Lee Keon-Joo
- Lee TH
- Lemmens R
- Lemmons R
- Leonard Hampton L.
- Lepik Kaido
- Levi CR
- Lewis Adam J.
- Lewis CM
- Leys D
- Li Jiang
- Li Liming
- Li LN
- Liaw Yi-Ching
- Liaw Yung-Po
- Liman Thomas
- Lin Kuang
- Lin WY
- Lind L
- Lindgren AG
- Lindgren CM
- Lindstrom S
- Linkohr B
- Lioutas V
- Liu YM
- Lledos M
- Llucia-Carol L
- Longstreth W. T.
- Lopez OL
- Lopez-Cancio E
- Lorentzen E
- Luijckx GJ
- Lv J
- MacDonald J
- Magi R
- Magnusson PK
- Maguire J
- Makoto H
- Malik Rainer
- Manichaikul Ani
- Markus Hugh S.
- Marston Nicholas A.
- Marti-Fabregas J
- Martinez-Majander N
- Martinsen AE
- Matsuda K
- Mayerhofer Ernst
- McArdle PF
- McCauley BM
- McDonough CW
- McKnight B
- Meitinger Thomas
- Melander O
- Menon V
- Meschia JF
- Metspalu A
- Milani Lili
- Millan M
- Millwood Iona Y.
- Minegishi N
- Mishra Aniket
- Mitchell Braxton D.
- Molina CA
- Montaner J
- Montellano Felipe A.
- Morange PE
- Morisaki Takayuki
- Morris AP
- Mosley Thomas H.
- Muino E
- Muller-Nurasyid M
- Munoz-Narbona L
- Murakami Y
- Nagai A
- Nalls Mike A.
- Namba Shinichi
- Nederkoorn PJ
- Nelis M
- Nielsen JB
- Niiranen Teemu J.
- Ninomiya Toshiharu
- Nordestgaard BG
- Nordestgaard BĂžrge G.
- Norrving B
- Nygaard Marianne
- O'Donnell CJ
- O'Donnell Martin J.
- Obach V
- Obiako R
- Ogbole G
- Ogishima S
- Okada Yukinori
- Olalere A
- Onland-Moret N. Charlotte
- Onland-Moret NC
- Osaigbovo G
- Ovbiagele Bruce
- Owolabi L
- Owolabi Mayowa O.
- Pankow JS
- Pankratz N
- Parati EA
- Parodi Livia
- Paré Guillaume
- Pattee JW
- Peddareddygari LR
- Pedersen LM
- Pedersen NL
- Pera J
- Perola M
- Peters Annette
- Peto R
- Pezzini A
- Pileggi S
- Posner Daniel C.
- Pozarickij A
- Prasad Kameshwar
- Prats-Sanchez L
- Psaty Bruce M.
- Pulit SL
- Putaala J
- Puurunen MK
- Rabionet R
- Rannikmae K
- Reiner A
- Reiner AP
- Rexrode KM
- Riaz Moeen
- Riba-Llena I
- Ribases M
- Ribo M
- Rice K
- Rich Stephen S.
- Ridker Paul M.
- Rissanen Ina L.
- Rolfs A
- Romero JR
- Roquer J
- Rosand Jonathan
- Rosendaal FR
- Roshchupkin Gennady V.
- Ross OA
- Rost NS
- Rothwell PM
- Rotter Jerome I.
- Rudd AG
- Ruff Christian T.
- Ruigrok Ynte M.
- Rundek Tatjana
- Rutten-Jacobs L
- Sabatine Marc S.
- Sacco Ralph L.
- Saillour-Glenisson F
- Sakaue S
- Sale MM
- Saleheen Danish
- Salomaa Veikko
- Sandset Else Charlotte
- Sanghera DK
- Sapkota BR
- Sarfo FS
- Sargurupremraj M
- Sargurupremraj Muralidharan
- Sarin AP
- Sarju R
- Sarnowski C
- Sasaki Makoto
- Satizabal Claudia L.
- Satoh M
- Sattar N
- Sawada N
- Schmidt Carsten O.
- Schmidt D
- Schmidt R
- Schminke U
- Schnohr P
- Segura T
- Serrano-Heras G
- Seshadri Sudha
- Sharma P
- Shi Mingyang
- Shimizu Atsushi
- Shiroma EJ
- Sibolt G
- Sigurdsson A
- Sigurdsson S
- Simonsick Eleanor M.
- Skogholt AH
- Sloane Kelly L.
- Slowik A
- Smith A
- Smith EN
- Smith Nicholas L.
- Sobrino T
- Sobue K
- Soderholm M
- Soriano-Tarraga C
- Srinivasasainagendra Vinodh
- Stanne TM
- Stefansson K
- Stevens B
- Stine OC
- Stott DJ
- Strauch K
- Strbian Daniel
- Suchon P
- Sudlow CLM
- Sumoy L
- Sun Yan V.
- Sung YJ
- Sutoh Yoichi
- Takai T
- Tanaka H
- Tang WH
- Tanislav C
- Tanno Kozo
- Tatlisumak Turgut
- Taylor KD
- Teumer A
- Thijs VNS
- Thomas LF
- Thomassen Jesper Qvist
- Thorleifsson G
- Thorsteinsdottir U
- Tiainen M
- Tiedt Steffen
- Tiwari Hemant K.
- Tomppo Liisa
- Torres-Aguila Nuria P.
- Touze E
- Traylor M
- Trompet Stella
- Trégouët David-Alexandre
- Tsugane S
- Tuladhar Anil Man
- Turman C
- Turnbull I
- TybjĂŠrg-Hansen Anne
- Tzourio C
- Uitterlinden AG
- Ungethum K
- Uvere E
- Valdimarsson EM
- van der Laan SW
- van der Lee SJ
- van Dijk EJ
- van Dijk GW
- van Duijn CM
- van Norden AGW
- van Oostenbrugge RJ
- van Rooij FGW
- van Setten J
- van Vugt M
- van Vugt Marion
- Vaura Felix C.
- Verma SS
- Verma Stefali S.
- Vermeer SE
- Vibo Riina
- Visser MC
- Vives-Bauza C
- Vlieg AV
- Volker U
- Volzke H
- Vonk JMJ
- Wahab K
- Wakai K
- Walters M
- Walters Robin G.
- Wang C
- Wang L
- Wang RQ
- Wareham NJ
- Wassertheil-Smoller Sylvia
- Weir D
- Wennberg Patrik
- Wermer MJH
- Wiggins Kerri L.
- Willer CJ
- Williams SR
- Wilson JG
- Wilson Peter W. F.
- Winsvold Bendik Slagsvold
- Wolfe CDA
- Wong QN
- Woo Daniel
- Worrall Bradford B.
- Xu Huichun
- Yaffe K
- Yamaji T
- Yang Chaojie
- Yang CR
- Yang Qiong
- Yonova-Doing Ekaterina
- Yoon Kyungheon
- Yu CQ
- Yusuf S
- Zand Ramin
- Zhou W
- Zonderman AB
- Zwart John-Anker
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 22/12/2022
- Field of study
Previous genome-wide association studies (GWASs) of stroke - the second leading cause of death worldwide - were conducted predominantly in populations of European ancestry(1,2). Here, in cross-ancestry GWAS meta-analyses of 110,182 patients who have had a stroke (five ancestries, 33% non-European) and 1,503,898 control individuals, we identify association signals for stroke and its subtypes at 89 (61 new) independent loci: 60 in primary inverse-variance-weighted analyses and 29 in secondary meta-regression and multitrait analyses. On the basis of internal cross-ancestry validation and an independent follow-up in 89,084 additional cases of stroke (30% non-European) and 1,013,843 control individuals, 87% of the primary stroke risk loci and 60% of the secondary stroke risk loci were replicated (P < 0.05). Effect sizes were highly correlated across ancestries. Cross-ancestry fine-mapping, in silico mutagenesis analysis(3), and transcriptome-wide and proteome-wide association analyses revealed putative causal genes (such as SH3PXD2A and FURIN) and variants (such as at GRK5 and NOS3). Using a three-pronged approach(4), we provide genetic evidence for putative drug effects, highlighting F11, KLKB1, PROC, GP1BA, LAMC2 and VCAM1 as possible targets, with drugs already under investigation for stroke for F11 and PROC. A polygenic score integrating cross-ancestry and ancestry-specific stroke GWASs with vascular-risk factor GWASs (integrative polygenic scores) strongly predicted ischaemic stroke in populations of European, East Asian and African ancestry(5). Stroke genetic risk scores were predictive of ischaemic stroke independent of clinical risk factors in 52,600 clinical-trial participants with cardiometabolic disease. Our results provide insights to inform biology, reveal potential drug targets and derive genetic risk prediction tools across ancestries.</p
Effect of crystal size on the skeletal isomerization of n-butene over H-FER zeolite
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Relative micro- and macrodiscsâa challenge in optical coherence tomography-based glaucoma diagnostics?
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Distribution and Epidemiologic Trends of HBV Genotypes and Subtypes in 14 Countries Neighboring China
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- Publication venue
- 'Kowsar Medical Institute'
- Publication date
- Field of study
Analysis of Relationship Between Manufacturing Flexibility and Lean Manufacturing Using Structural Equation Modelling
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- A Fercoq
- A Jain
- AK Sethi
- B Haque
- BM Byrne
- C Karlsson
- C Vasanthakumar
- D Gerwin
- D Gupta
- DA Toni
- DF Simpson
- DM Upton
- EP Jack
- FA Abdulmalek
- FF Suarez
- G Chauhan
- G Chauhan
- G Chauhan
- G Chauhan
- G Chauhan
- G Chauhan
- G Chauhan
- H Soriano-Meier
- IJ Chen
- J Bhamu
- J Browne
- J Hutchinson
- J Hyun
- J Motwani
- J Ranta
- JB Ullman
- JH Steiger
- JJ Bernardo
- JJ Coyle
- JK Liker
- JK Liker
- JP Shewchuk
- JP Womack
- JS Rothstein
- K Stecke
- L Mendes
- LL Koste
- LL Koste
- LT Hu
- M Ali
- M Ali
- M Goyal
- M Treleven
- MA Ketokivi
- MK Malhotra
- MK Nandakumar
- MP Sajan
- MW Browne
- N Asadi
- N Nagarur
- NC Tsourveloudis
- NL Hyer
- PM Podsakoff
- Q Zhang
- R Mishra
- R Shah
- R Shahu
- RB Kline
- RB Radhakrishna
- RE Schumacker
- RH Hayes
- RP Parker
- RV Ramasesh
- S Vinodh
- SP Kaur
- SP Kaur
- Sushil
- T Ohno
- TA Boyle
- TD Cook
- TL Saaty
- TP Singh
- V Sethi
- WC Jordan
- X Zhu
- Y Monden
- YP Gupta
- YP Gupta
- YS Pyoun
- Z Wei
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Comparison of in-Situ Hyperspectral and Landsat ETM+ Data for Chlorophyll-a Mapping in Case-II Water (Krishnarajapuram Lake, Bangalore)
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- Publication venue
- 'Springer Science and Business Media LLC'
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- Field of study
An amperometric biosensor based on poly(l-aspartic acid), nanodiamond particles, carbon nanofiber, and ascorbate oxidaseâmodified glassy carbon electrode for the determination of l-ascorbic acid
- Author
- A Jain
- AA Kyaw
- AM Schrand
- B Dalkıran
- B Mekassa
- B Mekassa
- BB Prasad
- C Kacar
- C Kaçar
- C Zhang
- D Kul
- D Li
- D Li
- F Li
- F Lisdat
- FA Harraz
- G CsiffĂĄry
- GH Wu
- H Chen
- H Xie
- H Zhang
- J Huang
- J Kulys
- J Lavanya
- J Zhang
- JR Camargo
- K Dhara
- L FernĂĄndez
- L Wei
- M Ates
- M Liu
- M Liu
- MMV Ramos
- N Chauhan
- N Chauhan
- N Chauhan
- N Shadjou
- NA Zambianco
- P Yang
- S Kumar
- S Pakapongpan
- S Yazdanparast
- SA Bekmezci
- T Dodevska
- T Nakamura
- TS Babu
- V Carralero
- V Kumar
- V SpĂnola
- W Ding
- WM Alshawafi
- Y Wen
- Y Wen
- YP Wen
- Z Zhu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
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