Phytochemical and Antimicrobial Studies of Strychnos wallichiana Steud Ex Dc

A preliminary phytochemical screening of seed and leaf of Strychnos wallichiana, an Asiatic woody liana species belongs to the family Loganiaceae revealed the presence of alkaloids, phenols, glycosides, flavonoids, saponins and sterols. Further, the HPLC chromatogram of alkaloid profile of seed has shown twelve prominent alkaloid peaks. Furthermore, the methanol and aqueous extracts were evaluated for in vitro antimicrobial properties against the selected bacteria and fungi at the concentration 2 mg/ml and 4 mg/ml, respectively using agar well diffusion assay. The findings have revealed considerable to significant inhibition activity of pathogens tested

Chamaecrista rotundifolia (Leguminosae - Caesalpinioideae) - A new record for India

Chamaecrista rotundifolia (Pers.) Greene, hitherto known to occur in tropical America is reported here as a new record for India from Bengaluru, Karnataka. A brief description with photographs of the herbarium specimen as well as the live plant is provided

Análise morfoanatômica comparativa da folha de Bauhinia forficata Link e B. variegata Linn. (Leguminosae, Caesalpinioideae) Comparative morphogical and anatomycal analyses of Bauhinia forficata Link and B. variegata Linn. (Leguminosae, Caesalpinioideae) leaves

Esse trabalho foi desenvolvido com o propósito de subsidiar o controle de qualidade das espécies medicinais Bauhinia forficata Link e B. variegata Linn. Essas foram coletadas em jardins e terrenos baldios de Curitiba, Paraná, Brasil. As amostras do limbo, pecíolo e pulvino foram fixadas em F.A.A. 50 e conservadas em etanol 70%. O seccionamento do material foi feito em micrótomo de rotação (material incluído em historresina) ou a mão livre e as lâminas foram montadas de forma permanente ou semipermanente. Foram realizadas análises em microscopia fotônica e eletrônica de varredura. A folha de B. forficata é alongada, com folíolos unidos em torno da metade do limbo, ápices agudos, superfície adaxial lisa e mucro entre os folíolos. Enquanto que, B. variegata possui folha mais larga que longa, com folíolos unidos na porção terminal do limbo e ápices obtusos. Nos pulvinos de B. variegata ocorrem camadas de colênquima, ausentes em B. forficata. O formato e a bainha de fibras dos pecíolos, em secção transversal, são distintos entre as espécies, assim como a distribuição dos estômatos e tricomas no limbo e a forma do bordo em secção transversal. B. variegata possui maior quantidade de idioblastos com drusas e compostos fenólicos. As características morfológicas e anatômicas de B. forficata e B. variegata contribuem para a identificação e diferenciação das espécies, sendo importantes para o controle de qualidade do material destinado à pesquisa e à indústria farmacêutica.<br>This work has been developed with the purpose of helping the quality control of the medicinal species Bauhinia forficata Link and B. variegata Linn., which were collected in gardens and vacant lots in Curitiba, Paraná, Brazil. The samples of leaf blade, petiole and pulvinus were fixed in FAA 50 and preserved in alcohol 70. The sectioning of the material was made in rotational microtome (with the material included in historesine) or manually and the blades were mounted in permanent or semipermanent way. Analyses in photonic and scanning electronic micros betscopy were performed. The leaf of B. forficata is elongated, with the leaflets united around the middle of the leaf blade, acute apices, smooth adaxial surface and mucroween the leaflets. The B. variegata, on the other hand, possesses a broader than long leaf, with the leaflets united in the terminal portion of the blade and obtuse apices. In the pulvinus of B. variegata there are collenchyma layers, which are absent in B. forficata. The shape and the petiole fibers sheath, in cross section, are distinct in both species, as well as the distribution of the stomata and trichomes in the leaf blade and the shape of the border in transversal section. B. variegata possesses a higher quantity of idioblasts with druses and phenolic compounds. The morphologic and anatomic characteristics of B. forficata an B. variegata contribute to the identification and distinction of the species and they are important for the control of the material destined to research and to the pharmaceutical industry

Synthetic RNAi triggers and their use in chronic hepatitis B therapies with curative intent

201901_a bcmaVersion of RecordPublishe

Chronic hepatitis B: Virology, natural history, current management and a glimpse at future opportunities

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