Narrow linewidth, single frequency semiconductor laser with a phase conjugate external cavity mirror

We measure the spectral characteristics of an external cavity semiconductor laser which uses a phase conjugate mirror for its external reflection. This device has significant advantages over the conventional external cavity system owing to the self-aligning nature of the phase conjugate mirror. The fiber delay line self-heterodyne technique is used to measure the fundamental linewidth for single mode operation of this device. It shows the linewidth to be at least as narrow as the instrumental resolution of 100 kHz

The Role of Entrepreneurship and Spirituality in the Provision of Elective Social Enterprise Courses in Business Schools

The final chapter in this section, chapter ten, Cherry Cheung, Sujun Fieldhouse and Caleb Kwong examine the extent to which the spirituality of a university may impact its decision to offer social enterprise courses as part of their business curriculum. Universities face increasing pressures from stakeholders to produce moral, civically aware and socially responsible citizens who will create positive change in their societies. Because of their concern and focus on social, economic, environmental and now spiritual ‘bottom-lines’, social enterprises courses are seen as one way of engaging in the conversations to examine transformational shifts in society. Using data from 494 business schools accredited by AACSB in the US, Cheung, Fieldhouse and Kwong found that, alongside structural differences, universities with higher entrepreneurship orientation, as well as the presence of spirituality markers, such as sustainability, diversity and religious orientations, are more likely to be offering social enterprise courses for business students, after controlling for other factors. This is an important finding, confirming that spirituality has a role to play in supporting a broader education experience that has the potential to develop socially responsible citizens who have the awareness to create transformational social changes. Thus, the study alerts the wider academic community of the contributions that social enterprise courses can make in creating social change, particularly for those without a strong emphasis of spirituality that may struggle to see the need to offer such courses

Solar neutrino interactions: Using charged currents at SNO to tell neutral currents at Super-Kamiokande

In the presence of flavor oscillations, muon and tau neutrinos can contribute to the Super-Kamiokande (SK) solar neutrino signal through the neutral current process \nu_{\mu,\tau} e^{-}\to \nu_{\mu,\tau} e^{-}. We show how to separate the \nu_e and \nu_{\mu,\tau} event rates in SK in a model independent way, by using the rate of the charged current process \nu_e d \to p p e^{-} from the Sudbury Neutrino Observatory (SNO) experiment, with an appropriate choice of the SK and SNO energy thresholds. Under the additional hypothesis of no oscillations into sterile states, we also show how to determine the absolute ^{8}B neutrino flux from the same data set, independently of the \nu_e survival probability.Comment: 14 pages (RevTeX), incl. 3 figures (epsf), submitted to Phys. ReV.

Improvement of myocardial perfusion reserve detected by cardiovascular magnetic resonance after direct endomyocardial implantation of autologous bone marrow cells in patients with severe coronary artery disease

<p>Abstract</p> <p>Background</p> <p>Recent studies suggested that bone marrow (BM) cell implantation in patients with severe chronic coronary artery disease (CAD) resulted in modest improvement in symptoms and cardiac function. This study sought to investigate the functional changes that occur within the chronic human ischaemic myocardium after direct endomyocardial BM cells implantation by cardiovascular magnetic resonance (CMR).</p> <p>Methods and Results</p> <p>We compared the interval changes of left ventricular ejection fraction (LVEF), myocardial perfusion reserve and the extent of myocardial scar by using late gadolinium enhancement CMR in 12 patients with severe CAD. CMR was performed at baseline and at 6 months after catheter-based direct endomyocardial autologous BM cell (n = 12) injection to viable ischaemic myocardium as guided by electromechanical mapping. In patients randomized to receive BM cell injection, there was significant decrease in percentage area of peri-infarct regions (-23.6%, <it>P </it>= <it>0.04</it>) and increase in global LVEF (+9.0%, <it>P </it>= <it>0.02</it>), the percentage of regional wall thickening (+13.1%, <it>P= 0.04</it>) and MPR (+0.25%, <it>P </it>= <it>0.03</it>) over the target area at 6-months compared with baseline.</p> <p>Conclusions</p> <p>Direct endomyocardial implantation of autologous BM cells significantly improved global LVEF, regional wall thickening and myocardial perfusion reserve, and reduced percentage area of peri-infarct regions in patients with severe CAD.</p

A Case Study on Online Learning and Digital Assessment in Times of Crisis

To minimise the adverse impact on student learning due to escalating social unrest started locally in June 2019 and the current COVID-19 pandemic, Hong Kong Baptist University has emphatically strengthened its strategic resolve in e-Learning deployment. With various measures and e-Learning initiatives rolled out, HKBU teachers gained more momentum in launching online classes and conducting e-Assessments with different e-Tools. Peer-sharing from teachers who have successfully implemented online classes and digital assessment was conducive to creating a culture to fast-track e-Learning adoption. This case study sheds light on how virtual teaching and learning have assisted HKBU teachers and students circumvent the recent crises. The study also identifies determining factors and challenges of adopting e-Learning strategies at the University

Comparative proteomic analysis of esophageal squamous cell carcinoma

Ranking as the fourth commonest cancer, esophageal squamous cell carcinoma (ESCC) represents one of the leading causes of cancer death in China. One of the main reasons for the low survival rate is that neoplasms in esophagus are not detected until they have invaded into surrounding tissues or spread throughout the body at advanced stages. A better understanding of the malignant mechanism and early diagnosis are important for fighting ESCC. In this study, we used proteomics to analyze ESCC tissues, aiming at defining the proteomic features implicated in the multistage progression of esophageal carcinogenesis. Proteins that exhibited significantly different expressions were identified by peptide mass fingerprinting and validated by Western blotting and reverse transcriptase-polymerase chain reaction. The protein changes were then correlated to the different grades of disease differentiation. Compared to those in adjacent normal epitheliums, the expression of 15 proteins including enolase, elongation factor Tu, isocitrate dehydrogenase, tubulin alpha-1 chain, tubulin beta-5 chain, actin (cytoplasmic 1), glyceraldehyde-3 phosphate dehydrogenase, tropomyosin isoform 4 (TPM4), prohibitin, peroxiredoxin 1 (PRX1), manganese-containing superoxide dismutase (MnSOD), neuronal protein, and transgelin was up-regulated; and the expression of five proteins including TPM1, squamous cell carcinoma antigen 1 (SCCA1), stratifin, peroxiredoxin 2 isoform a, and alpha B crystalline was down-regulated in cancer tissues with a statistical significance (p < 0.05). In addition, the differential expression of SCCA1, PRX1, MnSOD, TPM4, and prohibitin can be observed in precancerous lesions of ESCC. The expression of stratifin, prohibitin, and SCCA1 dropped with increasing dedifferentiation of ESCC. These data may suggest that these proteins contribute to the multistage process of carcinogenesis, tumor progression, and invasiveness of ESCC. © 2005 WILEY-VCH Verlag GmbH & Co. KGaA.postprin