152 research outputs found
Quasi-particle interference and superconducting gap in a high-temperature superconductor Ca2-xNaxCuO2Cl2
High-transition-temperature (high-Tc) superconductivity is ubiquitous in the
cuprates containing CuO2 planes but each cuprate has its own character. The
study of the material dependence of the d-wave superconducting gap (SG) should
provide important insights into the mechanism of high-Tc. However, because of
the 'pseudogap' phenomenon, it is often unclear whether the energy gaps
observed by spectroscopic techniques really represent the SG. Here, we report
spectroscopic imaging scanning tunneling microscopy (SI-STM) studies of
nearly-optimally-doped Ca2-xNaxCuO2Cl2 (Na-CCOC) with Tc = 25 ~ 28 K. They
enable us to observe the quasi-particle interference (QPI) effect in this
material, through which unambiguous new information on the SG is obtained. The
analysis of QPI in Na-CCOC reveals that the SG dispersion near the gap node is
almost identical to that of Bi2Sr2CaCu2Oy (Bi2212) at the same doping level,
while Tc of Bi2212 is 3 times higher than that of Na-CCOC. We also find that SG
in Na-CCOC is confined in narrower energy and momentum ranges than Bi2212. This
explains at least in part the remarkable material dependence of TcComment: 13pages, 4fig
Quantum oscillations from Fermi arcs
When a metal is subjected to strong magnetic field B nearly all measurable
quantities exhibit oscillations periodic in 1/B. Such quantum oscillations
represent a canonical probe of the defining aspect of a metal, its Fermi
surface (FS). In this study we establish a new mechanism for quantum
oscillations which requires only finite segments of a FS to exist. Oscillations
periodic in 1/B occur if the FS segments are terminated by a pairing gap. Our
results reconcile the recent breakthrough experiments showing quantum
oscillations in a cuprate superconductor YBCO, with a well-established result
of many angle resolved photoemission (ARPES) studies which consistently
indicate "Fermi arcs" -- truncated segments of a Fermi surface -- in the normal
state of the cuprates.Comment: 8 pages, 5 figure
Generalized joint density of states and its application to exploring the pairing symmetry of superconductors
We introduce a generalized joint density of states (GJDOS), which
incorporates the coherent factor into the JDOS, to study quasiparticle
interference (QPI) in superconductors. The intimate relation between the
Fourier-transformed local density of states and GJDOS is revealed: they corre-
spond respectively to the real and imaginary parts of a generalized
impurity-response function, and particularly share the same angular factors and
singular boundaries, as seen from our approximate analytic results for d-wave
superconductors. Remarkably, our numerical GJDOS analysis agrees well with the
QPI patten of d-wave cuprates and s\pm-wave iron-based superconductors.
Moreover, we illustrate that the present GJDOS scenario can uncover the sign
features of the superconducting gap and thus can be used to explore the
possible pairing symmetry of the KxFe2-ySe2 superconductors.Comment: 5 pages, 3 figure
QED_3 theory of underdoped high temperature superconductors II: the quantum critical point
We study the effect of gapless quasiparticles in a d-wave superconductor on
the T=0 end point of the Kosterlitz-Thouless transition line in underdoped
high-temperature superconductors. Starting from a lattice model that has
gapless fermions coupled to 3D XY phase fluctuations of the superconducting
order parameter, we propose a continuum field theory to describe the quantum
phase transition between the d-wave superconductor and the spin-density-wave
insulator. Without fermions the theory reduces to the standard Higgs scalar
electrodynamics (HSE), which is known to have the critical point in the
inverted XY universality class. Extending the renormalization group calculation
for the HSE to include the coupling to fermions, we find that the qualitative
effect of fermions is to increase the portion of the space of coupling
constants where the transition is discontinuous. The critical exponents at the
stable fixed point vary continuously with the number of fermion fields , and
we estimate the correlation length exponent (nu = 0.65) and the vortex field
anomalous dimension(eta_Phi=-0.48) at the quantum critical point for the
physical case N=2. The stable critical point in the theory disappears for the
number of Dirac fermions N > N_c, with N_c ~ 3.4 in our approximation. We
discuss the relationship between the superconducting and the chiral (SDW)
transitions, and point to some interesting parallels between our theory and the
Thirring model.Comment: 13 pages including figures in tex
Role of spinon and spinon singlet pair excitations on phase transitions in superconductors
We examine the roles of massless Dirac spinon and spin singlet pair
excitations on the phase transition in superconductors. Although the
massless spinon excitations in the presence of the spin singlet pair
excitations do not alter the nature of the phase transition at , that
is, the XY universality class, they are seen to induce an additional attractive
interaction potential between vortices, further stabilizing vortex-antivortex
pairs at low temperature for lightly doped high samples.Comment: 5 pages, 1 figur
Electronic structure in underdoped cuprates due to the emergence of a pseudogap
The phenomenological Green's function developed in the works of Yang, Rice
and Zhang has been very successful in understanding many of the anomalous
superconducting properties of the deeply underdoped cuprates. It is based on
considerations of the resonating valence bond spin liquid approximation and is
designed to describe the underdoped regime of the cuprates. Here we emphasize
the region of doping, , just below the quantum critical point at which the
pseudogap develops. In addition to Luttinger hole pockets centered around the
nodal direction, there are electron pockets near the antinodes which are
connected to the hole pockets by gapped bridging contours. We determine the
contours of nearest approach as would be measured in angular resolved
photoemission experiments and emphasize signatures of the Fermi surface
reconstruction from the large Fermi contour of Fermi liquid theory (which
contains hole states) to the Luttinger pocket (which contains hole
states). We find that the quasiparticle effective mass renormalization
increases strongly towards the edge of the Luttinger pockets beyond which it
diverges.Comment: 11 pages, 9 figure
The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility
Deubiquitinating enzymes are now emerging as potential therapeutic targets that control many cellular processes, but few have been demonstrated to control cell motility. Here, we show that ubiquitin-specific protease 17 (USP17) is rapidly and transiently induced in response to chemokines SDF-1/CXCL12 and IL-8/CXCL8 in both primary cells and cell lines, and that its depletion completely blocks chemokine-induced cell migration and cytoskeletal rearrangements. Using live cell imaging, we demonstrate that USP17 is required for both elongated and amoeboid motility, in addition to chemotaxis. USP17 has previously been reported to disrupt Ras localization and we now find that USP17 depletion blocks chemokine-induced subcellular relocalization of GTPases Cdc42, Rac and RhoA, which are GTPases essential for cell motility. Collectively, these results demonstrate that USP17 has a critical role in cell migration and may be a useful drug target for both inflammatory and metastatic disease
Mutation analysis of the MDM4 gene in German breast cancer patients
<p>Abstract</p> <p>Background</p> <p>MDM4 is a negative regulator of p53 and cooperates with MDM2 in the cellular response to DNA damage. It is unknown, however, whether <it>MDM4 </it>gene alterations play some role in the inherited component of breast cancer susceptibility.</p> <p>Methods</p> <p>We sequenced the whole <it>MDM4 </it>coding region and flanking untranslated regions in genomic DNA samples obtained from 40 German patients with familial breast cancer. Selected variants were subsequently screened by RFLP-based assays in an extended set of breast cancer cases and controls.</p> <p>Results</p> <p>Our resequencing study uncovered two <it>MDM4 </it>coding variants in 4/40 patients. Three patients carried a silent substitution at codon 74 that was linked with another rare variant in the 5'UTR. No association of this allele with breast cancer was found in a subsequent screening of 133 patients with bilateral breast cancer and 136 controls. The fourth patient was heterozygous for the missense substitution D153G which is located in a less conserved region of the MDM4 protein but may affect a predicted phosphorylation site. The D153G substitution only partially segregated with breast cancer in the family and was not identified on additional 680 chromosomes screened.</p> <p>Conclusion</p> <p>This study did not reveal clearly pathogenic mutations although it uncovered two new unclassified variants at a low frequency. We conclude that there is no evidence for a major role of <it>MDM4 </it>coding variants in the inherited susceptibility towards breast cancer in German patients.</p
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