Bilişim Etiği Öğretimi Uygulaması

The purpose of this study was to investigate effectiveness of “Information Technology (IT) Ethics Education Program” (BEÖP), to identify effects of this training on attitudes of students towards IT ethics and to evaluate attitudes of students towards this learning activity. A quasi-experimental pretest-posttest design was used in this study. For this study, a five-week education program consisting of subjects related to IT, ethics, IT ethics, privacy, intellectual property, copyright, patents, license agreements, freedom of speech and IT abuse was developed. Participants of the study were 48 students consisting of 26 girls and 22 boys from one middle school in Izmir in 2012-2013 Fall Semesters. In the study, in order to identify attitudes of students towards ethical use of IT, “IT Ethics with Real Life Case Studies Scale” (GYDSBE) was used. In order to find out the opinions of participants about this learning activity, “IT Ethics Education Program Questionnaire” (BEÖPÖG) was used. According to the research results, BEÖP has positive effects on attitudes of experiment group towards ethical use of IT. In addition to this, there is no significant difference between ethical use of IT and gender. Considering opinions of students about this learning activity, all students in experiment group stated that they all enjoyed participating in BEÖPBu araştırmanın amacı; hazırlanan “Bilişim Etiği Öğretim Programı”nın (BEÖP) öğrencilerin bilişim teknolojilerinin etik kullanımına yönelik tutumlarına etkisini belirlemek ve öğrencilerin bu uygulamaya yönelik görüşlerini değerlendirmektir. Bu araştırma, öntest-sontest kontrol gruplu yarı deneysel bir çalışmadır. Araştırma kapsamında bilişim teknolojisi, etik, bilişim etiği, mahremiyet, fikri mülkiyet, telif hakları, patentler, lisans anlaşmaları, ifade özgürlüğü ve bilişim suçları konularını kapsayan beş haftalık bir öğretim programı hazırlamıştır. Araştırmaya 2012–2013 eğitim öğretim yılında İzmir ilinde 6. sınıfta öğrenim görmekte olan 26 kız ve 22 erkek olmak üzere toplam 48 öğrenci katılmıştır. Araştırmada katılımcıların bilişim teknolojilerinin etik kullanımlarına yönelik tutumlarını belirlemek için “Gerçek Yaşam Durum Senaryolarıyla Bilişim Etiği (GYDSBE) Ölçeği”; öğretim programına yönelik görüşlerini değerlendirmek için ise “Bilişim Etiği Öğretim Programı Öğrenci Görüşleri (BEÖPÖG) Anketi” kullanılmıştır. Araştırma sonuçlarına göre BEÖP öğrencilerinin bilişim teknolojilerinin etik kullanımına yönelik tutumlarını olumlu yönde etkilerken cinsiyete göre anlamlı bir fark bulunmamıştır. Deney grubu öğrencilerinin tamamı BEÖP uygulamasına katılmanın hoşlarına gittiğini belirtmiştir

Investigation of the expression levels of CPEB4, APC, TRIP13, EIF2S3, EIF4A1, IFNg, PIK3CA and CTNNB1 genes in different stage colorectal tumors

Background/aim: The aim of the study is to assess expression levels of CPEB4, APC, TRIP13, EIF2S3, EIF4A1, IFNg, PIK3CA and CTNNB1 genes in tumors and peripheral bloods of colorectal cancer patients in stages I–IV. Materials and methods: The mRNA levels of the genes were determined in tumor tissues and peripheral blood samples of 45 colorectal cancer patients and colon tissues and peripheral blood samples of 5 healthy individuals. Real-time polymerase chain reaction method was used for the analysis. Results: The mRNA level of the CPEB4 gene was significantly downregulated in colorectal tumor tissues and was upregulated in the peripheral blood of colorectal cancer patients relative to the controls (P < 0.05). APC mRNA level was significantly downregulated in tissues and upregulated in the peripheral blood (P < 0.05). TRIP13 mRNA level was upregulated in peripheral blood and also significantly upregulated in colorectal tumor tissues (P < 0.05). EIF2S3 mRNA level was upregulated in tissues and also significantly upregulated in peripheral blood (P < 0.05). PIK3CA mRNA level was downregulated in tissues and upregulated in peripheral blood. EIF4A1 mRNA level was downregulated in tissues and significantly upregulated in peripheral blood (P < 0.05). CTNNB1 mRNA level was downregulated in tissues and upregulated in peripheral blood. IFNg mRNA level was upregulated in both colorectal cancer tumor tissues and peripheral blood. Conclusion: TRIP13 and CPEB4 mRNA up regulation in the peripheral blood of patients with colorectal cancer may be a potential target for early stage diagnosis. In addition to this evaluation, although there is not much study on EIF2S3 and EIF4A1 mRNA changes in cases with colorectal cancer, upregulation in peripheral blood draws attention in our study. These data will shed light on the new comprehensive studies

Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

Dysphagia after thyridectomy and diagnosis confusion: Achalasia case report

6 ay önce tiroidektomi operasyonu geçiren bir hastanın, geçirilen cerrahi girişim sonucu sağ inferior larengial siniri yaralanmış, hastada progresif kilo kaybı gelişmiş ve akalazya tanısının konulması gecikmiştir. Bu nedenle kilo kaybı ve yutma güçlüğü olan bir hastada geçirilmiş boyun cerrahisi olsa bile özofagus motilite bozukluklarının bulunabileceği hatırda tutulmalıdır.The right inferior larengeal nerve was injured during the operation in a patient with thyridecctomy six months ago. After this operation weight loss wass developed progressively and the diagnoses of achalasia was delayed. For that reason it must be considered that, in a patient with weight loss and disphagia the motility disorder of esaphagus may exist inspide of the history of neck surgery

Staged abdominal closure in strengthened abdomen (case report and review of the literature)

Operasyon sonrası abdomenin güçlükle kapatılması durumunda oluşabilecek intra¬abdominal basınç artışının renal, pulmoner ve kardiak etkileri nedeniyle, abdominal kompartman sendromu gelişmesi ve fatal sonuçları beklenmelidir. İleus, hipoksi, reperfüzyon ve ödem sonucu olarak intra-abdominal basınç artışı nedenleri arasında kabul edilebilir. Kliniğimizde, sigmoid kolon rezeksiyonunu takip eden ileal torsiyona bağlı ileus gelişmiş 80 yaşındaki bir erkek hastaya, Bogota Bag ve takiben abdomeni kapatma amacıyla abdominal rekonstriksiyon yapıldı. Bu yöntemle abdominal kompartman sendromu gelişmesi engellendi. Bu olgu nedeniyle, güç kapanan batında abdominal kompartman sendromu gelişmemesi için uygulanabilecek aşamalı batın kapatma yöntemlerini gözden geçirmek ve klinikte yaygın olarak kullanılmayan rektus ön kılıfı transpozisyonunu tanıtmak amaçlandı.The abdominal compartment syndrome and its fatal results should be expected in difficulty on closure of the abdomen because of the renal, cardiac, pulmonary effect of abdominal hypertension. Ileus could be accepted as reason of intra-abdominal hypertension that result of hypoxia, reperfusion injury and oedema. In our clinic, Bogota Bag and abdominal reconstruction were applied to 80 years of male patient with the ileal torsion resulted as ileus, followed sigmoid colonic resection. The progress of abdominal compartment syndrome was prevented by this process. Because of this case, in this report it was aimed to review of the stage to stage abdominal clousure methods for the prevention of abdominal compartment syndrome progress and to present fascia of rectus abdominis transpositioning which is not applied commonly

Ex situ liver resection and partial liver autotransplantation for advanced cholangiocarcinoma

Surgery is the only known curative treatment option for cholangiocarcinoma. Ex situ liver surgery and autotransplantation are promising approaches in cases that cannot be treated by conventional methods and particularly in the presence of centrally localized liver tumors as well as tumors that invade the main vascular structures. A 53-year-old female patient presented with abdominal pain and nausea. Abdominal tomography showed a tumoral mass lesion that filled the left lobe of the liver and invaded the left hepatic vein and the inferior vena cava. Cholangiocarcinoma diagnosis was reached based on biopsy findings, and the patient was scheduled for surgery as positron emission tomography did not indicate any other disease focus. The patient underwent ex situ liver resection and autotransplantation. She was discharged on the 7th postoperative day. A 68-year-old male presented with abdominal pain, weakness, and weight loss. Laboratory analysis indicated elevated carbohydrate antigen 19-9: 400 U/ml and alpha-fetoprotein (AFP): 2000 U/ml, and there was no other pathology. Abdominal tomography showed a mass that filled the center of the liver and invaded the left hepatic vein and the inferior vena cava. Pathological findings of the biopsy sample were reported as combined hepatocellular-cholangiocellular carcinoma. The patient's AFP levels continued to increase despite transcatheter arterial chemoembolization and radiofrequency ablation therapy. Surgery was decided as indocyanine green clearance test, and the result was 8.5%. He underwent ex situ liver resection and autotransplantation. Unfortunately, he died on the 4th postoperative day due to respiratory failure. Ex vivo liver resection and partial liver autotransplantation should be considered for the surgical treatment of locally advanced cholangiocarcinomas that invaded the main vascular structures

Ex situ Liver Resection and Partial Liver Autotransplantation for Advanced Cholangiocarcinoma

Surgery is the only known curative treatment option for cholangiocarcinoma. Ex situ&nbsp;liver surgery and autotransplantation are promising approaches in cases that cannot be treated by conventional methods and particularly in the presence of centrally localized liver tumors as well as tumors that invade the main vascular structures. A 53-year-old female patient presented with abdominal pain and nausea. Abdominal tomography showed a tumoral mass lesion that filled the left lobe of the liver and invaded the left hepatic vein and the inferior vena cava. Cholangiocarcinoma diagnosis was reached based on biopsy findings, and the patient was scheduled for surgery as positron emission tomography did not indicate any other disease focus. The patient underwent&nbsp;ex situ&nbsp;liver resection and autotransplantation. She was discharged on the 7th&nbsp;postoperative day. A 68-year-old male presented with abdominal pain, weakness, and weight loss. Laboratory analysis indicated elevated carbohydrate antigen 19-9: 400 U/ml and alpha-fetoprotein (AFP): 2000 U/ml, and there was no other pathology. Abdominal tomography showed a mass that filled the center of the liver and invaded the left hepatic vein and the inferior vena cava. Pathological findings of the biopsy sample were reported as combined hepatocellular-cholangiocellular carcinoma. The patient's AFP levels continued to increase despite transcatheter arterial chemoembolization and radiofrequency ablation therapy. Surgery was decided as indocyanine green clearance test, and the result was 8.5%. He underwent&nbsp;ex situ&nbsp;liver resection and autotransplantation. Unfortunately, he died on the 4th&nbsp;postoperative day due to respiratory failure.&nbsp;Ex vivo&nbsp;liver resection and partial liver autotransplantation should be considered for the surgical treatment of locally advanced cholangiocarcinomas that invaded the main vascular structures

An alternative technique in the control of massive presacral rectal bleeding: fixation of GORE-TEX® aortic patch

The presacral venous system is located under the pelvic fascia covering the anterior of the sacrum and consists of two lateral sacral veins, middle sacral vein, and the veins that communicate them. The presacral venous system can be easily damaged and causes serious bleeding which is difficult to control and may cause intraoperative mortality. Its incidence varies between 3% and 9.4%. Although several methods have been tried to control presacral bleeding, the definitive method of treatment has not yet been identified. We present here our alternative technique in control of massive presacral massive bleeding developed from the presacral plexus secondary to the traction of the specimen during the dissection. The bleeding could not be controlled despite the use of all technical possibilities such as packing, ligation, and hemostatic agents. Bleeding control was provided by GORE‑TEX® graft. We conclude that fıxatıon of GORE‑TEX® aortic patch should be kept in mind for uncontrolled massive presacral bleeding.Keywords: GORE‑TEX® graft, presacral bleeding, rectal cance