Novel Design of High-Gain Planar Dipole-Array Antenna for RFID 2.45 GHz

This paper presents a novel high-gain planar dipole-array antenna for 2.45 GHz which consists of four planar dipole elements placed in two parallel lines. Phase retardation of each element is set by feeding network to form controllable radiation direction. The radiation pattern of the array is discussed according to Arrays Theorem. The measured −10 dB band is from 2.3 GHz to 2.57 GHz, and peak gain in this band is 7.5 dBi. The gain can even reach 10.5 dBi after installing additional ground. The proposed antenna has advantages of high gain, controllable direction, and planarity which are suitable for 2.45 GHz RFID base station

Novel Design of High-Gain Planar Dipole-Array Antenna for RFID 2.45 GHz

This paper presents a novel high-gain planar dipole-array antenna for 2.45 GHz which consists of four planar dipole elements placed in two parallel lines. Phase retardation of each element is set by feeding network to form controllable radiation direction. The radiation pattern of the array is discussed according to Arrays Theorem. The measured −10 dB band is from 2.3 GHz to 2.57 GHz, and peak gain in this band is 7.5 dBi. The gain can even reach 10.5 dBi after installing additional ground. The proposed antenna has advantages of high gain, controllable direction, and planarity which are suitable for 2.45 GHz RFID base station

miR-142-5p in Bone Marrow-Derived Mesenchymal Stem Cells Promotes Osteoporosis Involving Targeting Adhesion Molecule VCAM-1 and Inhibiting Cell Migration

Osteoporosis is a systemic bone metabolic disease that is highly prevalent in the elderly population, particularly in postmenopausal women, which results in enhanced bone fragility and an increased susceptibility to fractures. However, the underlying molecular pathogenesis mechanisms still remain to be further elucidated. In this study, in a rat ovariectomy- (OVX-) induced postmenopausal osteoporosis model, aberrant expression of a microRNA miR-142-5p and vascular cell adhesion molecule 1 (VCAM-1) was found by RNA sequencing analysis and qRT-PCR. Using a dual-luciferase reporter assay, we found that miR-142-5p can bind to and decrease expression of VCAM-1 mRNA. Such reduction was prohibited when the miR-142-5p binding site in VCAM-1 3′UTR was deleted, and Western blotting analyses validated the fact that miR-142-5p inhibited the expression of VCAM-1 protein. Bone marrow-derived mesenchymal stem cells (BMMSCs) transfected with miR-142-5p showed a significantly decreased migration ability in a Transwell migration assay. Collectively, these data indicated the important role of miR-142-5p in osteoporosis development involving targeting VCAM-1 and inhibiting BMMSC migration

miR-142-5p in Bone Marrow-Derived Mesenchymal Stem Cells Promotes Osteoporosis Involving Targeting Adhesion Molecule VCAM-1 and Inhibiting Cell Migration

Osteoporosis is a systemic bone metabolic disease that is highly prevalent in the elderly population, particularly in postmenopausal women, which results in enhanced bone fragility and an increased susceptibility to fractures. However, the underlying molecular pathogenesis mechanisms still remain to be further elucidated. In this study, in a rat ovariectomy- (OVX-) induced postmenopausal osteoporosis model, aberrant expression of a microRNA miR-142-5p and vascular cell adhesion molecule 1 (VCAM-1) was found by RNA sequencing analysis and qRT-PCR. Using a dual-luciferase reporter assay, we found that miR-142-5p can bind to and decrease expression of VCAM-1 mRNA. Such reduction was prohibited when the miR-142-5p binding site in VCAM-1 3′UTR was deleted, and Western blotting analyses validated the fact that miR-142-5p inhibited the expression of VCAM-1 protein. Bone marrow-derived mesenchymal stem cells (BMMSCs) transfected with miR-142-5p showed a significantly decreased migration ability in a Transwell migration assay. Collectively, these data indicated the important role of miR-142-5p in osteoporosis development involving targeting VCAM-1 and inhibiting BMMSC migration