Profiling Behavior of Intruders on Enterprise Honeynet: Deployment and Analysis

Network and information security continues to be one of the largest areas that require greater attention and improvement over the current state of infrastructure within enterprise information systems. Intruders to enterprise networks are no longer just hacking for fun or to show off their programming skills; rather they are now doing it for profit-making motives. As a result, developing profiles for the behavior of intruders, trespassing upon business information systems within an enterprise networking environment, has become a primary focus of cyber-security research recently. In the proposed on-going project, we deploy a novel honeynet system using advanced virtualization technologies, in order to collect the forensic evidence of an attack, by allowing attackers to interact with compromised computers in a real enterprise network. We then analyze the behavior of intruders in order to investigate and compare their hidden linkages as compared with enterprise networks, and the attacker(s)’ potential group structures, including attributes such as geographic distribution and service communities, thus providing strategies for enterprise-network administrators to stay protected against malicious attacks from external intruders. Preliminary results on the proposed research is very promising, showing intruders’ behaviors over one month were distributed across over 60 different countries, and our work demonstrated that the most popular service intruders like use to interact with is the very HTTP Web itself

Far-Field Tunable Nano-focusing Based on Metallic Slits Surrounded with Nonlinear-Variant Widths and Linear-Variant Depths of Circular Dielectric Grating

In this work, we design a new tunable nanofocusing lens by the linear-variant depths and nonlinear-variant widths of circular grating for far field practical applications. The constructively interference of cylindrical surface plasmon launched by the subwavelength metallic structure can form a subdiffraction-limited focus, and the focal length of the this structures can be adjusted if the each groove depth and width of circular grating are arranged in traced profile. According to the numerical calculation, the range of focusing points shift is much more than other plasmonic lens, and the relative phase of emitting light scattered by surface plasmon coupling circular grating can be modulated by the nonlinear-variant width and linear-variant depth. The simulation result indicates that the different relative phase of emitting light lead to variant focal length. We firstly show a unique phenomenon for the linear-variant depths and nonlinear-variant widths of circular grating that the positive change and negative change of the depths and widths of grooves can result in different of variation trend between relative phases and focal lengths. These results paved the road for utilizing the plasmonic lens in high-density optical storage, nanolithography, superresolution optical microscopic imaging, optical trapping, and sensing.Comment: 14pages,9figure

Possible Involvement of µ

Recently μ opioid receptor (MOR) has been shown to be closely associated with depression. Here we investigated the action of Shuyu, a Chinese herbal prescription, on repeated restraint stress induced depression-like rats, with specific attention to the role of MOR and the related signal cascade. Our results showed that repeated restraint stress caused significant depressive-like behaviors, as evidenced by reduced body weight gain, prolonged duration of immobility in forced swimming test, and decreased number of square-crossings and rearings in open field test. The stress-induced depression-like behaviors were relieved by Shuyu, which was accompanied by decreased expression of MOR in hippocampus. Furthermore, Shuyu upregulated BDNF protein expression, restored the activity of CREB, and stimulated MEK and ERK phosphorylation in hippocampus of stressed rats. More importantly, MOR is involved in the effects of Shuyu on these depression-related signals, as they can be strengthened by MOR antagonist CTAP. Collectively, these data indicated that the antidepressant-like properties of Shuyu are associated with MOR and the corresponding CREB, BDNF, MEK, and ERK signal pathway. Our study supports clinical use of Shuyu as an effective treatment of depression and also suggests that MOR might be a target for treatment of depression and developing novel antidepressants

3-Meth­oxy-4-methyl-1H-1,2,4-triazol-5(4H)-one monohydrate

In the title hydrate, C4H7N3O2·H2O, all the non-H atoms lie on a crystallographic mirror plane. The H atoms of both methyl groups are disordered over two sets of sites. In the crystal, N—H⋯Ow and Ow—H⋯Ok (w = water and k = ketone) hydrogen bonds link the components into (010) sheets

Syntheses, Crystal Structures and Xanthine Oxidase Inhibitory Activity of Aroylhydrazones

A series of hydrazones, (E)-N’-(4-hydroxy-3-methoxybenzylidene)-4-nitrobenzohydrazide (1), (E)-4-(dimethylamino)-N’-(4-hydroxy-3-methoxybenzylidene)benzohydrazide (2), N'-(2-hydroxy-5-methylbenzylidene)-4-nitrobenzohydrazide (3) and 2-fluoro-N’-(2-hydroxy-5-methylbenzylidene)benzohydrazide (4), were prepared and structurally characterized by elemental analysis, IR and 1H NMR spectra, and X-ray single crystal determination. The xanthine oxidase inhibitory activities of the compounds were investigated. Among the compounds, N'-(3-methoxybenzylidene)-4-nitrobenzohydrazide (1) showed the strongest activity. Docking simulations were performed to insert the compounds into the crystal structure of xanthine oxidase at the active site and to investigate the probable binding modes

catena-Poly[[{2-[(2-hy­droxy­eth­yl)imino­meth­yl]-6-meth­oxy­phenolato}copper(II)]-μ-thio­cyanato]

In the title thio­cyanate-bridged polynuclear copper(II) complex, [Cu(C10H12NO3)(NCS)]n, the Cu atom is five-coordinated in a square-pyramidal geometry, with one phenolato O, one imino N and one hy­droxy O atom of a Schiff base ligand and one thio­cyanato N atom defining the basal plane, and with one thio­cyanato S atom occupying the apical position. In the crystal structure, pairs of adjacent complex mol­ecules are linked through inter­molecular O—H⋯O hydrogen bonds into dimers. The dimers are further linked via Cu⋯S inter­actions, forming two-dimensional layers parallel to the bc plane