Axial Force Analysis and Roll Contour Configuration of Four-High CVC Mill

In order to analyze the influence of technical parameters on work roll axial force of four-high continuous variable crown (CVC) mill, the deformation analyzing model with top roll system and strip was established based on influence function method. Then a CVC work roll curve designing scheme was proposed and it was carried out on some cold rolling mill considering the requirement of comprehensive work roll axial force minimization. The status of comprehensive work roll axial force is improved considering the rolling schedule that is beneficial to the roller bearing. Corresponding to the newly designed work roll contour, the backup roll end chamfer was designed considering comprehensive performance of interroll stress concentration, comprehensive work roll axial force, and strip shape control ability. The distribution of roll wear with newly designed backup roll contour is more even according to the field application data. The newly established roll configuration scheme is beneficial to four-high CVC mill

Numerical Simulation Analysis of Water Injection Seepage Law in Micro Porous Structure of Coal

In this paper, a nano Voxel X-ray 3D microscope is used to scan the long flame coal samples and to reconstruct the 3D pore structure by the use of microscopic computed tomography. With image segmentation technique, a model of micro-pore structure of coal is obtained from the reconstructed coal. With different planes selected as seepage inlets, a numerical simulation of low-pressure water seepage is conducted. Studies show that water pressure gradually decreases along the direction of water seepage and reaches the maximum at the pore-pipes with good connectivity near the inlet. Due to the difference between the structure and development direction of pores in the three dimensions, there is an optimal seepage outlet that is most appropriately corresponding to each seepage inlet. When different planes are selected as seepage inlets, the velocity of each seepage outlet is positively correlated with the seepage mass flow rate at the outlet

Combined analysis of mRNA expression of ERCC1, BAG-1, BRCA1, RRM1 and TUBB3 to predict prognosis in patients with non-small cell lung cancer who received adjuvant chemotherapy

<p>Abstract</p> <p>Background</p> <p>The aim of this study was to investigate prognostic value of excision repair cross-complementing 1 (ERCC1), BCL2-associated athanogene (BAG-1), the breast and ovarian cancer susceptibility gene 1 (BRCA1), ribonucleotide reductase subunit M1 (RRM1) and class III β-tubulin (TUBB3) in patients with non-small cell lung cancer (NSCLC) who received platinum- based adjuvant chemotherapy.</p> <p>Methods</p> <p>Messenger RNA expressions of these genes were examined in 85 tumor tissues and 34 adjacent tissue samples using semi-quantitative RT-PCR. The expressions of these five genes were analyzed in relation to chemotherapy and progression-free survival (PFS) and overall survival (OS). Seventy-four patients were enrolled into chemotherapy.</p> <p>Results</p> <p>Patients with ERCC1 or BAG-1 negative expression had a significantly longer PFS (<it>P </it>= 0.001 and <it>P </it>= 0.001) and OS (<it>P </it>= 0.001 and <it>P </it>= 0.001) than those with positive expression. Patients with negative ERCC1 and BAG-1 expression benefited more from platinum regimen (<it>P </it>= 0.001 and <it>P </it>= 0.002). Patients with BRCA1 negative expression might have a longer OS (<it>P </it>= 0.052), but not PFS (<it>P </it>= 0.088) than those with BRCA1 positive expression. A significant relationship was observed between the mRNA expression of ERCC1 and BAG-1 (<it>P </it>= 0.042). In multivariate analysis, ERCC1 and BAG-1 were significantly favorable factors for PFS (<it>P </it>= 0.018 and <it>P </it>= 0.017) and OS (<it>P </it>= 0.027 and <it>P </it>= 0.022).</p> <p>Conclusions</p> <p>ERCC1 and BAG-1 are determinants of survival after surgical treatment of NSCLC, and its mRNA expression in tumor tissues could be used to predict the prognosis of NSCLC treated by platinum.</p

Experimental Realization of Nonadiabatic Holonomic Single-Qubit Quantum Gates with Two Dark Paths in a Trapped Ion

For circuit-based quantum computation, experimental implementation of universal set of quantum logic gates with high-fidelity and strong robustness is essential and central. Quantum gates induced by geometric phases, which depend only on global properties of the evolution paths, have built-in noise-resilience features. Here, we propose and experimentally demonstrate nonadiabatic holonomic single-qubit quantum gates on two dark paths in a trapped $^{171}\mathrm{Yb}^{+}$ ion based on four-level systems with resonant drives. We confirm the implementation with measured gate fidelity through both quantum process tomography and randomized benchmarking methods. Meanwhile, we find that nontrivial holonomic two-qubit quantum gates can also be realized within current experimental technologies. Compared with previous implementations on three-level systems, our experiment share both the advantage of fast nonadiabatic evolution and the merit of robustness against systematic errors, and thus retains the main advantage of geometric phases. Therefore, our experiment confirms a promising method for fast and robust holonomic quantum computation.Comment: 13 pages, 5 figure

A Simplified Flexible Multibody Dynamics for a Main Landing Gear with Flexible Leaf Spring

The dynamics of multibody systems with deformable components has been a subject of interest in many different fields such as machine design and aerospace. Traditional rigid-flexible systems often take a lot of computer resources to get accurate results. Accuracy and efficiency of computation have been the focus of this research in satisfying the coupling of rigid body and flex body. The method is based on modal analysis and linear theory of elastodynamics: reduced modal datum was used to describe the elastic deformation which was a linear approximate of the flexible part. Then rigid-flexible multibody system was built and the highly nonlinearity of the mass matrix caused by the limited rotation of the deformation part was approximated using the linear theory of elastodynamics. The above methods were used to establish the drop system of the leaf spring type landing gear of a small UAV. Comparisons of the drop test and simulation were applied. Results show that the errors caused by the linear approximation are acceptable, and the simulation process is fast and stable