Observation of the antimatter helium-4 nucleus at RHIC

We present the observation of the \Heebar nucleus, the heaviest antinucleus observed to date. In total, 18 \Heebar counts were detected at the STAR experiment at RHIC in 10$^{9}$ recorded Au+Au collisions at beam energies of $\sqrt{s_{NN}}$ = 200 GeV and 62 GeV. The background has been estimated, and the misidentification probability is found to be lower than 10$^{-11}$.Comment: 4 pages, 3 figures, to appear as proceedings of QM2011 conference at Annecy, Franc

Critical magnetic field in holographic superconductor in Gauss-Bonnet gravity with Born-Infeld electrodynamics

In the paper using matching method in the probe limit, we investigate some properties of holographic superconductor in Gauss-Bonnet gravity with Born-Infeld electrodynamics . We discuss the effects of the Gauss-Bonnet coupling \a and Born-Infeld parameter $b$ on the critical temperature and condensate. We find that both of \a and $b$ make the critical temperature decrease, which implies the condensate harder to form. Moreover we study the magnetic effect on holographic superconductor and obtain that the ratio between the critical magnetic field and the square of the critical temperature increases from zero as the temperature is lowered below the critical value $T_c$, which agrees well with the former results. We also find the critical magnetic field is indeed affected by Gauss-Bonnet coupling, but not by Born-Infeld parameter.Comment: 13 pages, 5 figure

A range extension for Haplomitrium mnioides (Lindb.) R.M.Schust.

Haplomitrium mnioides (Lindb.) R.M.Schust. is reported as new to Hainan Island. A continuous distribution of H. mnioides from west (Thailand) to east (Japan) is confirmed. Habitat pictures and a distribution map are provided

Discovery of Novel Triplex DNA Binding Ligands

Triplex DNA formation has attracted interest in anti-gene therapy as it can interfere with many pathogenic activities, including replication halt and gene expression regulation. Triplex DNA is not as stable as duplex DNA under physiological conditions. Small molecules, known as anti-gene enhancers, have been used to facilitate the formation of triplex DNA. In the present work, I report the discovery of a novel class of small molecules that can bind to triplex DNA with high affinities but do not influence the structures of duplex DNA

Cognitive Impairment Progression Analysis by Comparison of Clinical and Cognitive Scales, including Visualization using Agent-Based Simulation Approach

Alzheimer’s disease has been identified as the 6th leading cause of death in United States in 2015. One-third seniors die with Alzheimer’s and other dementia. Only 45% of AD patients report being told of their diagnosis. Staging the severity of AD is needed of no delay.The “preclinical” phase of AD is known to be a long-term progression process towards severe cognitive impairment. Clinical and Cognitive scaling methods, especially Clinical Dementia Rating (CDR) and Mini-mental State Examination (MMSE), are widely used in mapping the stage of cognitive impairment status. Many studies have also identified important clinical and physiological risk factors, such as age, smoking status, blood pressure, total serum cholesterol, current impairment status, etc. To discuss a better prediction method of AD for mild cognitive impairment patients, a longitudinal study of the impact of these influential factors is essential. The objective of this research is to firstly analyze the accuracy of both methods and secondly to propose a method that gives higher prediction accuracy. The main contribution of this paper is that we gave a thorough analysis on comparison of CDR and MMSE, commented on which method works better based upon personal demographic performance and brought up a pattern recognition model to predict the probability of patients reaching the unfavorable outcome, i.e. dementia, over time. We gained a method that achieves high accuracy by combining the regression model and MMSE cognitive scales. An agent-based simulation model was brought up to visualize the change of cognitive impairment status of patients over time, in various populations.Master of Science in EngineeringIndustrial and Systems Engineering, College of Engineering and Computer ScienceUniversity of Michigan-Dearbornhttp://deepblue.lib.umich.edu/bitstream/2027.42/136068/1/Cognitive Impairment Progression Analysis by Comparison of Clinical and Cognitive Scales, including Visualization using Agent-Based Simulation Approach.pd