Joint Extraction of Entities and Relations Based on a Novel Tagging Scheme

Joint extraction of entities and relations is an important task in information extraction. To tackle this problem, we firstly propose a novel tagging scheme that can convert the joint extraction task to a tagging problem. Then, based on our tagging scheme, we study different end-to-end models to extract entities and their relations directly, without identifying entities and relations separately. We conduct experiments on a public dataset produced by distant supervision method and the experimental results show that the tagging based methods are better than most of the existing pipelined and joint learning methods. What's more, the end-to-end model proposed in this paper, achieves the best results on the public dataset

THE VALUE OF CHIEF DATA OFFICER PRESENCE ON FIRM PERFORMANCE

In the era of big data, there are more and more organizations trying to establish a new breed of executive, Chief Data Officer (CDO), to identify new business opportunity from data assets and optimize corporate revenue. However, the relationship between CDO presence and firm’s financial performance has not been rigorously studied and validated in literature. Based on upper echelon theory and strategic change perspectives, we examined the impact of pre-performance on the CDO appointment, as well as the CDO presence on post-performance. We collected a multi-industry dataset of 68 firms with a CDO position. The results show that the return on assets (ROA) is positively related to CDO appointment, while, market to book ratio (M/B) is negatively related to CDO appointment. In addition, we found that firms with CDO have superior financial performance than their peers who do not. This study provides an initial step towards understanding the empirical linkages between CDO presence and firm performance

Self-regulation of homework behavior: Homework management at the secondary school level

ABSTRACT. The authors examined empirical models of variables posited to predict homework management at the secondary school level. The participants were 866 eighth-grade students from 61 classes and 745 eleventh-grade students from 46 classes. Most of the variance in homework management occurred at the student level, with affective attitude and homework interest appearing as 2 significant predictors at the class level. At the student level, homework management was positively associated with learning-oriented reasons, affective attitude, self-reported grade, family homework help, homework interest, teacher feedback, and adult-oriented reasons. On the other hand, homework management was negatively associated with time spent watching television. In addition, Black girls, compared with Black boys, were more likely to manage their homework assignments

Safety Situation and Policy on Mountain Highway of China

Abstract: The mountainous area approximately composes 2/3 of Chinese nation. The mountain road safety situation is important to the whole country. The paper starts from the characteristic of mountain road accidents. Through the studies the mountain road accidents shows different. There is higher death rate and more traffic accidents. In the major accidents, more accidents are fall to the roadside and the vehicles type is complex. By the actual survey in Sichuan Chongqing Yunnan and Guizhou four province, the mountain road safety facilities are checked. The characteristics and problems are found. Through the road traffic accidents analysis and the existing status of mountain safety facilities, the mountain road safety technology policies are given, which will provide a reference for managers

Doxycycline Regulated Induction of AKT in Murine Prostate Drives Proliferation Independently of p27 Cyclin Dependent Kinase Inhibitor Downregulation

The PI3 kinase/AKT pathway has been shown to increase degradation of the p27 cyclin dependent kinase inhibitor through phosphorylation of consensus AKT sites on p27 and SKP2, and AKT driven proliferation may be checked by feedback mechanisms that increase p27 expression and induce senescence. However, these AKT sites are not conserved in mouse, and it has not been clear whether AKT negatively regulates murine p27. Transgenic mice with a probasin promoter controlled prostate specific reverse tetracycline transactivator (ARR2Pb-rtTA) were generated and used to achieve doxycycline inducible expression of a tetracycline operon regulated constitutively active myristoylated AKT1 transgene (tetO-myrAKT). Doxycycline induction of myrAKT occurred within 1 day and rapidly induced proliferation (within 4 days) and the development of prostatic intraepithelial neoplasia (PIN) lesions in ventral prostate, which did not progress to prostate cancer. Cells in these lesions expressed high levels of p27, had increased proliferation, and there was apoptosis of centrally located cells. Doxycycline withdrawal resulted in apoptosis of cells throughout the lesions and rapid clearing of hyperplastic glands, confirming in vivo the critical antiapoptotic functions of AKT. Significantly, analyses of prostates immediately after initiating doxycycline treatment further showed that p27 expression was rapidly increased, coincident with the induction of myrAKT and prior to the development of hyperplasia and PIN. These findings establish in vivo that murine p27 is not negatively regulated by AKT and indicate that proliferation in PI3 kinase/AKT pathway driven mouse models is mediated by p27 independent mechanisms that may be distinct from those in human. Further studies using prostate specific doxycycline regulated transgene expression may be useful to assess the acute effects of inducing additional transgenes in adult murine prostate epithelium, and to assess the requirements for continued transgene expression in transgene induced tumors