High photo-excited carrier multiplication by charged InAs dots in AlAs/GaAs/AlAs resonant tunneling diode

We present an approach for the highly sensitive photon detection based on the quantum dots (QDs) operating at temperature of 77K. The detection structure is based on an AlAs/GaAs/AlAs double barrier resonant tunneling diode combined with a layer of self-assembled InAs QDs (QD-RTD). A photon rate of 115 photons per second had induced 10nA photocurrent in this structure, corresponding to the photo-excited carrier multiplication factor of 10^7. This high multiplication factor is achieved by the quantum dot induced memory effect and the resonant tunneling tuning effect of QD-RTD structure.Comment: 10 pages,5 figures. Submitted to Applied Physics Letter

Dose-effect relationship analysis of TCM based on deep Boltzmann machine and partial least squares

A dose-effect relationship analysis of traditional Chinese Medicine (TCM) is crucial to the modernization of TCM. However, due to the complex and nonlinear nature of TCM data, such as multicollinearity, it can be challenging to conduct a dose-effect relationship analysis. Partial least squares can be applied to multicollinearity data, but its internally extracted principal components cannot adequately express the nonlinear characteristics of TCM data. To address this issue, this paper proposes an analytical model based on a deep Boltzmann machine (DBM) and partial least squares. The model uses the DBM to extract nonlinear features from the feature space, replaces the components in partial least squares, and performs a multiple linear regression. Ultimately, this model is suitable for analyzing the dose-effect relationship of TCM. The model was evaluated using experimental data from Ma Xing Shi Gan Decoction and datasets from the UCI Machine Learning Repository. The experimental results demonstrate that the prediction accuracy of the model based on the DBM and partial least squares method is on average 10% higher than that of existing methods

Comparative Study Of Complex Network Community Structure Algorithms In network Pharmacology Analysis

Community structure is an extremely important characteristic of complex networks composed of network pharmacology. The mining of network community structure is of great importance in many fields such as biology, computer science and sociology. In recent years, for different types of large-scale complex networks, researchers had proposed many algorithms for finding community structures. This paper reviewed some of the most representative algorithms in the field of network pharmacology, and focused on the analysis of the improved algorithms based on the modularity index and the new algorithms that could reflect the level and overlap of the community. Finally, a benchmark was established to measure the quality of the community classification algorithm

Comparative Study Of Complex Network Community Structure Algorithms In network Pharmacology Analysis

Community structure is an extremely important characteristic of complex networks composed of network pharmacology. The mining of network community structure is of great importance in many fields such as biology, computer science and sociology. In recent years, for different types of large-scale complex networks, researchers had proposed many algorithms for finding community structures. This paper reviewed some of the most representative algorithms in the field of network pharmacology, and focused on the analysis of the improved algorithms based on the modularity index and the new algorithms that could reflect the level and overlap of the community. Finally, a benchmark was established to measure the quality of the community classification algorithm

Research on Hybrid Feature Selection Method Based on Iterative Approximation Markov Blanket

The basic experimental data of traditional Chinese medicine are generally obtained by high-performance liquid chromatography and mass spectrometry. The data often show the characteristics of high dimensionality and few samples, and there are many irrelevant features and redundant features in the data, which bring challenges to the in-depth exploration of Chinese medicine material information. A hybrid feature selection method based on iterative approximate Markov blanket (CI_AMB) is proposed in the paper. The method uses the maximum information coefficient to measure the correlation between features and target variables and achieves the purpose of filtering irrelevant features according to the evaluation criteria, firstly. The iterative approximation Markov blanket strategy analyzes the redundancy between features and implements the elimination of redundant features and then selects an effective feature subset finally. Comparative experiments using traditional Chinese medicine material basic experimental data and UCI’s multiple public datasets show that the new method has a better advantage to select a small number of highly explanatory features, compared with Lasso, XGBoost, and the classic approximate Markov blanket method