Human Performance Modeling For Two-Dimensional Dwell-Based Eye Pointing

Recently, Zhang et al. (2010) proposed an effective performance model for dwell-based eye pointing. However, their model was based on a specific circular target condition, without the ability to predict the performance of acquiring conventional rectangular targets. Thus, the applicability of such a model is limited. In this paper, we extend their one-dimensional model to two-dimensional (2D) target conditions. Carrying out two experiments, we have evaluated the abilities of different model candidates to find out the most appropriate one. The new index of difficulty we redefine for 2D eye pointing (IDeye) can properly reflect the asymmetrical impact of target width and height, which the later exceeds the former, and consequently the IDeyemodel can accurately predict the performance for 2D targets. Importantly, we also find that this asymmetry still holds for varying movement directions. According to the results of our study, we provide useful implications and recommendations for gaze-based interactions

Mutations that promote furin-independent growth of Semliki Forest virus affect p62–E1 interactions and membrane fusion

AbstractThe enveloped alphavirus Semliki Forest virus (SFV) infects cells via a low pH-triggered membrane fusion reaction mediated by the E1 protein. E1's fusion activity is regulated by its heterodimeric interaction with a companion membrane protein E2. Mature E2 protein is generated by furin processing of the precursor p62. Processing destabilizes the heterodimer, allowing dissociation at acidic pH, E1 conformational changes, and membrane fusion. We used a furin-deficient cell line, FD11, to select for SFV mutants that show increased growth in the absence of p62 processing. We isolated and characterized 7 such pci mutants (p62 cleavage independent), which retained the parental furin cleavage site but showed significant increases in their ability to carry out membrane fusion in the p62 form. Sequence analysis of the pci mutants identified mutations primarily on the E2 protein, and suggested sites important in the interaction of p62 with E1 and the regulation of fusion

Synthesis and optical property of one-dimensional spinel ZnMn2O4 nanorods

Spinel zinc manganese oxide (ZnMn2O4) nanorods were successfully prepared using the previously synthesized α-MnO2 nanorods by a hydrothermal method as template. The nanorods were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, UV-Vis absorption, X-ray photoelectron spectroscopy, surface photovoltage spectroscopy, and Fourier transform infrared spectroscopy. The ZnMn2O4 nanorods in well-formed crystallinity and phase purity appeared with the width in 50-100 nm and the length in 1.5-2 μm. They exhibited strong absorption below 500 nm with the threshold edges around 700 nm. A significant photovoltage response in the region below 400 nm could be observed for the nanorods calcined at 650 and 800°C

STUDY ON EARTHQUAKE DAMAGE MECHANISM OF AQUEDUCT STRUCTURE BASED ON DIFFERENT BOUNDARY

Numerically simulating an infinite domain foundation is an important method for solving structural dynamics problems. This paper introduces several artificial dynamic boundaries commonly used in the study of structural dynamics, and elaborates the theory and methods of the dynamic infinite element method boundary (IEMB) and viscous–spring artificial boundary (VSAB). The capacity of different boundary effects on seismic waves energy absorption is verified by establishing a layered half-space model. An irrigation aqueduct is taken as a research object. The IEMB, VSAB, and fixed boundary (FB) models are established and the Concrete Damaged Plasticity (CDP) constitutive is introduced, which is aimed at studying the dynamic failure mechanism and the rules of damage development to the aqueduct structure during the seismic duration. The results for the IEMB and VSAB show better energy absorption for the incident waves and a better simulation result for the damping effect of the far field foundation than that of the FB. Comparing the maximum displacement response rules of the three boundaries, it is seen that the maximum displacement response values of the VSAB and dynamic IEMB increased by 6%–48% and 9%–35%, respectively, over the FB. The calculation results of the VSAB are similar to that of the IEMB. The difference between the maximum acceleration response values is 2%–17% whereas the difference between the maximum displacement response values is 0.4%–19%. The IEMB studied in this paper provides a theoretical reference for large–scale building boundary treatment in structural dynamics calculations

STUDY ON EARTHQUAKE DESTRUCTION MODE OF THE LARGEST CANAL CROSSING HIGHWAY BRIDGE BASED ON IEM BOUNDARY IN SOUTH-TO-NORTH WATER DIVERSION

  To study the dynamic failure mechanism and damage development law of highway bridge structure under the boundary effect in the process of seismic dynamic duration, the Wenchang Highway Bridge with the largest canal crossing in the South-to-North Water Diversion is taken as an example for seismic design analysis. Based on the finite element and infinite element coupling theory, the infinite element method boundary is introduced, the concrete damage plasticity is introduced, and the half-space free field model is established to study the energy dispersion phenomenon of waves in the boundary and the absorption effect of the infinite element method boundary on wave energy is verified. Under different peak acceleration intensities, the seismic response analysis of the bridge structure was carried out. The results show that: Under the action of selected artificial waves, the damage location of the bridge mainly concentrated in the junction of the box girder supported by the pier, the bottom of the pier and the junction of the pier and beam. The damage tends to develop downward near the bottom of the box girder. The damage at both ends of the beam extends from both ends to the middle. And the bottom and top of the pier have penetrating damage. These are weak points in seismic design. At a horizontal peak acceleration of 0.6g, in addition to damage to the pier column, damage also occurred to the bottom of the box girder. Therefore, when the horizontal peak acceleration of the seismic wave is greater than 0.6g, the failure of the bottom of the box girder is paid attention to. Moreover, the IEM boundary has a good control effect on the far-field energy dissipation of the wave, which is simpler and more efficient than the viscous–spring boundary

Understanding How Low Vision People Read Using Eye Tracking

While being able to read with screen magnifiers, low vision people have slow and unpleasant reading experiences. Eye tracking has the potential to improve their experience by recognizing fine-grained gaze behaviors and providing more targeted enhancements. To inspire gaze-based low vision technology, we investigate the suitable method to collect low vision users' gaze data via commercial eye trackers and thoroughly explore their challenges in reading based on their gaze behaviors. With an improved calibration interface, we collected the gaze data of 20 low vision participants and 20 sighted controls who performed reading tasks on a computer screen; low vision participants were also asked to read with different screen magnifiers. We found that, with an accessible calibration interface and data collection method, commercial eye trackers can collect gaze data of comparable quality from low vision and sighted people. Our study identified low vision people's unique gaze patterns during reading, building upon which, we propose design implications for gaze-based low vision technology.Comment: In Proceedings of the 2023 CHI Conference on Human Factors in Computing Systems (CHI '23