A Case Study of Mass Transport during the East-West Oscillation of the Asian Summer Monsoon Anticyclone

We use ERA-Interim reanalysis, MLS observations, and a trajectory model to examine the chemical transport and tracers distribution in the Upper Troposphere and Lower Stratosphere (UTLS) associated with an east-west oscillation case of the anticyclone in 2016. The results show that the spatial distribution of water vapor (H2O) was more consistent with the location of the anticyclone than carbon monoxide (CO) at 100 hPa, and an independent relative high concentration center was only found in H2O field. At 215 hPa, although the anticyclone center also migrated from the Tibetan Mode (TM) to the Iranian Mode (IM), the relative high concentration centers of both tracers were always colocated with regions where upward motion was strong in the UTLS. When the anticyclone migrated from the TM, air within the anticyclone over Tibetan Plateau may transport both westward and eastward but was always within the UTLS. The relative high concentration of tropospheric tracers within the anticyclone in the IM was from the east and transported by the westward propagation of the anticyclone rather than being lifted from surface directly. Air within the relative high geopotential height centers over Western Pacific was partly from the main anticyclone and partly from lower levels

Path Generation for Wheeled Robots Autonomous Navigation on Vegetated Terrain

Wheeled robot navigation has been widely used in urban environments, but little research has been conducted on its navigation in wild vegetation. External sensors (LiDAR, camera etc.) are often used to construct point cloud map of the surrounding environment, however, the supporting rigid ground used for travelling cannot be detected due to the occlusion of vegetation. This often causes unsafe or not smooth path during planning process. To address the drawback, we propose the PE-RRT* algorithm, which effectively combines a novel support plane estimation method and sampling algorithm to generate real-time feasible and safe path in vegetation environments. In order to accurately estimate the support plane, we combine external perception and proprioception, and use Multivariate Gaussian Processe Regression (MV-GPR) to estimate the terrain at the sampling nodes. We build a physical experimental platform and conduct experiments in different outdoor environments. Experimental results show that our method has high safety, robustness and generalization

Towards Efficient Communications in Federated Learning: A Contemporary Survey

In the traditional distributed machine learning scenario, the user's private data is transmitted between nodes and a central server, which results in great potential privacy risks. In order to balance the issues of data privacy and joint training of models, federated learning (FL) is proposed as a special distributed machine learning with a privacy protection mechanism, which can realize multi-party collaborative computing without revealing the original data. However, in practice, FL faces many challenging communication problems. This review aims to clarify the relationship between these communication problems, and focus on systematically analyzing the research progress of FL communication work from three perspectives: communication efficiency, communication environment, and communication resource allocation. Firstly, we sort out the current challenges existing in the communications of FL. Secondly, we have compiled articles related to FL communications, and then describe the development trend of the entire field guided by the logical relationship between them. Finally, we point out the future research directions for communications in FL

Searching for new globular clusters in M 31 with Gaia EDR3

We found 50 new globular cluster (GC) candidates around M\,31 with Gaia Early Data Release 3 (EDR3), with the help from Pan-STARRS1 DR1 magnitudes and Pan-Andromeda Archaeological Survey (PAndAS) images. Based on the latest Revised Bologna Catalog and \textit{simbad}, we trained 2 Random Forest (RF) classifiers, the first one to distinguish extended sources from point sources and the second one to further select GCs from extended sources. From 1.85 million sources of $16^m{<}g{<}19.5^m$ and within a large area of $\sim$392\,deg$^2$ around M\,31, we selected 20,658 extended sources and 1,934 initial GC candidates. After visual inspection of the PAndAS images to eliminate the contamination of non-cluster sources, particularly galaxies, we finally got 50 candidates. These candidates are divided into 3 types (\textbf{a}, \textbf{b}, \textbf{c}) according to their projected distance $D$ to the center of M\,31 and their probability to be a true GC, $P_{GC}$, which is calculated by our second RF classifier. Among these candidates, 14 are found to be associated (in projection) with the large-scale structures within the halo of M\,31. We also provided several simple parameter criteria for selecting extended sources effectively from the Gaia EDR3, which can reach a completeness of 92.1\% with a contamination fraction lower than 10\%

Enterovirus 71 induces degradation of TRIM38, a potential E3 ubiquitin ligase

<p>Abstract</p> <p>Background</p> <p>The tripartite motif (TRIM) proteins are a family of more than 70 members in human. However, only a few of them have been well studied. The TRIM proteins contain the conserved RING, B-box, coiled-coil, and SPRY domains, most of which are involved in protein ubiquitination. TRIM38 is a member of the TRIM protein family, which we studied in more detail here as its functions are largely unknown.</p> <p>Results</p> <p>Our study shows that, similar to other TRIM family members, TRIM38 is localized in the cytoplasm. TRIM38 increases ubiquitination of other cellular proteins and catalyzes self-ubiquitination. TRIM38 also promotes K63- and K48-linked ubiquitination of cellular proteins. An intact RING domain is important for the functions of TRIM38. In addition, enterovirus 71 infection induces TRIM38 degradation.</p> <p>Conclusions</p> <p>Our observations demonstrate that TRIM38 has E3 ubiquitin ligase activity and can be degraded during virus infection. These findings may provide insight into innate immune signaling pathways.</p

Exogenous nitric oxide stimulates early egress of Eimeria tenella sporozoites from primary chicken kidney cells in vitro

Egress plays a vital role in the life cycle of apicomplexan parasites including Eimeria tenella, which has been attracting attention from various research groups. Many recent studies have focused on early egress induced by immune molecules to develop a new method of apicomplexan parasite elimination. In this study, we investigated whether nitric oxide (NO), an immune molecule produced by different types of cells in response to cytokine stimulation, could induce early egress of eimerian sporozoites in vitro. Eimeria tenella sporozoites were extracted and cultured in primary chicken kidney cells. The number of sporozoites egressed from infected cells was analyzed by flow cytometry after treatment with NO released by sodium nitroferricyanide (II) dihydrate. The results showed that exogenous NO stimulated the rapid egress of E. tenella sporozoites from primary chicken kidney cells before replication of the parasite. We also found that egress was dependent on intra-parasitic calcium ion (Ca2+) levels and no damage occurred to host cells after egress. The virulence of egressed sporozoites was significantly lower than that of fresh sporozoites. The results of this study contribute to a novel field examining the interactions between apicomplexan parasites and their host cells, as well as that of the clearance of intracellular pathogens by the host immune system