Mapping the scientific research on integrated care: a bibliometric and social network analysis

BackgroundIntegrated care (IC) is the cornerstone of the sustainable development of the medical and health system. A thorough examination of the existing scientific literature on IC is essential for assessing the present state of knowledge on this subject. This review seeks to offer an overview of evidence-based knowledge, pinpoint existing knowledge gaps related to IC, and identify areas requiring further research.MethodsData were retrieved from the Web of Science Core Collection, from 2010 to 2020. Bibliometrics and social network analysis were used to explore and map the knowledge structure, research hotspots, development status, academic groups and future development trends of IC.ResultsA total of 7,501 articles were obtained. The number of publications on IC was rising in general. Healthcare science services were the most common topics. The United States contributed the highest number of articles. The level of collaboration between countries and between authors was found to be relatively low. The keywords were stratified into four clusters: IC, depression, integrative medicine, and primary health care. In recent years, complementary medicine has become a hotspot and will continue to be a focus.ConclusionThe study provides a comprehensive analysis of global research hotspots and trends in IC, and highlights the characteristics, challenges, and potential solutions of IC. To address resource fragmentation, collaboration difficulties, insufficient financial incentives, and poor information sharing, international collaboration needs to be strengthened to promote value co-creation and model innovation in IC. The contribution of this study lies in enhancing people’s understanding of the current state of IC research, guiding scholars to discover new research perspectives, and providing valuable references for researchers and policymakers in designing and implementing effective IC strategies

Properties of Graphene Oxide/Epoxy Resin Composites

The graphene oxide (GO) was obtained by pressurized oxidation method using natural graphite as raw materials. Then the GO/epoxy resin composites were prepared by casting. The mechanical and damping properties of composites were studied. As a result, the impact intensity of GO/epoxy resin composites was prominently improved with the content of the graphene oxide increasing. The glass transition temperature decreased and the damping capacity is improved

Methodology for quantum logic gate constructions

We present a general method to construct fault-tolerant quantum logic gates with a simple primitive, which is an analog of quantum teleportation. The technique extends previous results based on traditional quantum teleportation (Gottesman and Chuang, Nature {\bf 402}, 390, 1999) and leads to straightforward and systematic construction of many fault-tolerant encoded operations, including the $\pi/8$ and Toffoli gates. The technique can also be applied to the construction of remote quantum operations that cannot be directly performed.Comment: 17 pages, mypsfig2, revtex. Revised with a different title, a new appendix for clarifying fault-tolerant preparation of quantum states, and various minor change

Rapid and Visual Detection of Monkey B Virus Based on Recombinase Polymerase Amplification

Monkey B virus (BV) infection in humans and other macaque species has a mortality rate of approximately 80%. Because BV infects humans through bites, scratches, and other injuries inflicted by macaques, the simple and rapid diagnosis of BV in field laboratories is of great importance to protect veterinarians, laboratory researchers, and support personnels from the threat of infection. Two recombinase polymerase amplification (RPA) assays with a closed vertical flow (VF) visualization strip (RPA-VF-UL27 and RPA-VF-US6) were developed that target two conserved genes combined with a one-off, closed visualization strip device. We compared the sensitivities and specificities of the two assays after optimization of the reaction conditions. The performance of RPA-VF-US6 at room temperature was determined to evaluate its potential in point-of-care (POC) testing. RPA-VF-US6 specifically detected the positive plasmid control (rather than nucleic acids of herpesviruses) with a detection limit of 28 copies, while RPA-VF-UL27 had cross-reactivity with HSV-1, but even 3.4 copies of plasmid standards were readout by this assay. Moreover, RPA-VF-US6 had excellent performance at room temperature (the detection limit was 2,800 plasmid copies), indicating the potential of RPA-VF-US6 in POC testing. We developed two RPA assays for BV visualization diagnosis. RPA-VF-US6 is a simple, rapid, and specific detection method for BV. The entire reaction can be performed at a constant temperature within 30 min, suggesting the potential of RPA-VF-US6 for POC testing in field laboratories without sophisticated instruments

Experimental Realization of A Two Bit Phase Damping Quantum Code

Using nuclear magnetic resonance techniques, we experimentally investigated the effects of applying a two bit phase error detection code to preserve quantum information in nuclear spin systems. Input states were stored with and without coding, and the resulting output states were compared with the originals and with each other. The theoretically expected result, net reduction of distortion and conditional error probabilities to second order, was indeed observed, despite imperfect coding operations which increased the error probabilities by approximately 5%. Systematic study of the deviations from the ideal behavior provided quantitative measures of different sources of error, and good agreement was found with a numerical model. Theoretical questions in quantum error correction in bulk nuclear spin systems including fidelity measures, signal strength and syndrome measurements are discussed.Comment: 21 pages, 17 figures, mypsfig2, revtex. Minor changes made to appear in PR

Coupling coordination evaluation and driving path of digital economy and carbon emission efficiency in China: A fuzzy-set qualitative comparative analysis based on 30 provinces.

Enhancing the level of coupling coordination between the digital economy (DIE) and carbon emission efficiency (CEE) is not only an inevitable choice for achieving the goals of energy conservation and emission reduction and promoting green development in China, but also a key path to implementing China's "Double Carbon" strategy. Based on the relevant statistical data of 30 provincial-level regions in China from the period covering 2011 to 2019, this paper empirically analyzed the coupling coordination between the DIE and CEE and its influencing factors. In this study, an improved coupling coordination degree (CCD) model was used to evaluate the degree of the coupling and coordinated development of the DIE and CEE in provincial regions of China. Finally, based on the Technology-Organization-Environment (TOE) framework, a fuzzy-set qualitative comparative analysis (fsQCA) method was employed to identify the realization path of the coupling and coordinated development of the DIE and CEE from the perspective of configuration. The results demonstrated that the coupling coordination between the DIE and CCE in China demonstrated a gradual upward trend, and exhibited regional differences, showing a decreasing trend of east > middle > west. Regarding the influencing factors, no single influencing factor could act as a necessary condition for the high CCD, the coupling and coordinated development of the DIE and CEE is a multifactorial synergy. There were five paths for the high degree of coupling coordination between the DIE and CEE, which were divided into three types: organization-environment-led type, environment-led type, and technology-organization-led type. Furthermore, technological innovation level and industrial structure could substitute for one another in some conditions, and environmental regulation and economic development level were synchronized. These conclusions provide a theoretical basis for countries to formulate policies to promote the coupling and coordinated development of their DIE and CEE