230 research outputs found
Fatigue Reliability Assessment of Orthotropic Bridge Decks under Stochastic Truck Loading
A steady traffic growth has posed a threat to the fatigue safety of existing bridges. Uncertainties in traffic flows add to the challenge of an accurate fatigue safety assessment. This article utilizes a stochastic traffic load model to evaluate the fatigue reliability of orthotropic steel bridge decks. The traffic load model is simulated by site-specific weigh-in-motion measurements. A response surface method is presented to solve the time-consuming problem caused by hotspot stress simulations in the finite element model. Applications of the stochastic traffic load model for probabilistic modeling and fatigue reliability assessment are demonstrated in the case study of a steel box-girder bridge. Numerical results indicate that the growth rate of the gross vehicle weight leads to a rapid decrease of the fatigue reliability in comparison to the traffic volume growth. Even though the traffic volume growth is rapid, the control of overloaded trucks in comparison to the traffic volume is an effective way to ensure the fatigue safety of the steel bridges.National Basic Research Program of ChinaNational Science Foundation of ChinaKey Research Program in Civil Engineering from Changsha University of Science and Technolog
WeSinger 2: Fully Parallel Singing Voice Synthesis via Multi-Singer Conditional Adversarial Training
This paper aims to introduce a robust singing voice synthesis (SVS) system to
produce very natural and realistic singing voices efficiently by leveraging the
adversarial training strategy. On one hand, we designed simple but generic
random area conditional discriminators to help supervise the acoustic model,
which can effectively avoid the over-smoothed spectrogram prediction and
improve the expressiveness of SVS. On the other hand, we subtly combined the
spectrogram with the frame-level linearly-interpolated F0 sequence as the input
for the neural vocoder, which is then optimized with the help of multiple
adversarial conditional discriminators in the waveform domain and multi-scale
distance functions in the frequency domain. The experimental results and
ablation studies concluded that, compared with our previous auto-regressive
work, our new system can produce high-quality singing voices efficiently by
fine-tuning different singing datasets covering from several minutes to a few
hours. A large number of synthesized songs with different timbres are available
online https://zzw922cn.github.io/wesinger2 and we highly recommend readers to
listen to them.Comment: accepted at ICASSP 202
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Gab2 deficiency suppresses high-fat diet-induced obesity by reducing adipose tissue inflammation and increasing brown adipose function in mice.
Obesity is caused by a long-term imbalance between energy intake and consumption and is regulated by multiple signals. This study investigated the effect of signaling scaffolding protein Gab2 on obesity and its relevant regulation mechanism. Gab2 knockout (KO) and wild-type (WT) mice were fed with a standard diet (SD) or high-fat diet (HFD) for 12 weeks. The results showed that the a high-fat diet-induced Gab2 expression in adipose tissues, but deletion of Gab2 attenuated weight gain and improved glucose tolerance in mice fed with a high-fat diet. White adipose tissue and systemic inflammations were reduced in HFD-fed Gab2 deficiency mice. Gab2 deficiency increased the expression of Ucp1 and other thermogenic genes in brown adipose tissue. Furthermore, the regulation of Gab2 on the mature differentiation and function of adipocytes was investigated in vitro using primary or immortalized brown preadipocytes. The expression of brown fat-selective genes was found to be elevated in differentiated adipocytes without Gab2. The mechanism of Gab2 regulating Ucp1 expression in brown adipocytes involved with its downstream PI3K (p85)-Akt-FoxO1 signaling pathway. Our research suggests that deletion of Gab2 suppresses diet-induced obesity by multiple pathways and Gab2 may be a novel therapeutic target for the treatment of obesity and associated complications
LE-SSL-MOS: Self-Supervised Learning MOS Prediction with Listener Enhancement
Recently, researchers have shown an increasing interest in automatically
predicting the subjective evaluation for speech synthesis systems. This
prediction is a challenging task, especially on the out-of-domain test set. In
this paper, we proposed a novel fusion model for MOS prediction that combines
supervised and unsupervised approaches. In the supervised aspect, we developed
an SSL-based predictor called LE-SSL-MOS. The LE-SSL-MOS utilizes pre-trained
self-supervised learning models and further improves prediction accuracy by
utilizing the opinion scores of each utterance in the listener enhancement
branch. In the unsupervised aspect, two steps are contained: we fine-tuned the
unit language model (ULM) using highly intelligible domain data to improve the
correlation of an unsupervised metric - SpeechLMScore. Another is that we
utilized ASR confidence as a new metric with the help of ensemble learning. To
our knowledge, this is the first architecture that fuses supervised and
unsupervised methods for MOS prediction. With these approaches, our
experimental results on the VoiceMOS Challenge 2023 show that LE-SSL-MOS
performs better than the baseline. Our fusion system achieved an absolute
improvement of 13% over LE-SSL-MOS on the noisy and enhanced speech track. Our
system ranked 1st and 2nd, respectively, in the French speech synthesis track
and the challenge's noisy and enhanced speech track.Comment: accepted in IEEE-ASRU202
X-ray Near Field Speckle: Implementation and Critical Analysis
We have implemented the newly-introduced, coherence-based technique of x-ray
near-field speckle (XNFS) at 8-ID-I at the Advanced Photon Source. In the near
field regime of high-brilliance synchrotron x-rays scattered from a sample of
interest, it turns out, that, when the scattered radiation and the main beam
both impinge upon an x-ray area detector, the measured intensity shows
low-contrast speckles, resulting from interference between the incident and
scattered beams. We built a micrometer-resolution XNFS detector with a high
numerical aperture microscope objective and demonstrate its capability for
studying static structures and dynamics at longer length scales than
traditional far field x-ray scattering techniques. Specifically, we
characterized the structure and dynamics of dilute silica and polystyrene
colloidal samples. Our study reveals certain limitations of the XNFS technique,
which we discuss.Comment: 53 pages, 16 figure
High-Mobility and Bias-Stable Field-Effect Transistors Based on Lead-Free Formamidinium Tin Iodide Perovskites
Electronic devices based on tin halide perovskites often exhibit a poor operational stability. Here, we report an additive engineering strategy to realize high-performance and stable field-effect transistors (FETs) based on 3D formamidinium tin iodide (FASnI3) films. By comparatively studying the modification effects of two additives, i.e., phenethylammonium iodide and 4-fluorophenylethylammonium iodide via combined experimental and theoretical investigations, we unambiguously point out the general effects of phenethylammonium (PEA) and its fluorinated derivative (FPEA) in enhancing crystallization of FASnI3 films and the unique role of fluorination in reducing structural defects, suppressing oxidation of Sn2+ and blocking oxygen and water involved defect reactions. The optimized FPEA-modified FASnI3 FETs reach a record high field-effect mobility of 15.1 cm2/(V·s) while showing negligible hysteresis. The devices exhibit less than 10% and 3% current variation during over 2 h continuous bias stressing and 4200-cycle switching test, respectively, representing the best stability achieved so far for all Sn-based FETs.</p
High-Mobility and Bias-Stable Field-Effect Transistors Based on Lead-Free Formamidinium Tin Iodide Perovskites
Electronic devices based on tin halide perovskites often exhibit a poor operational stability. Here, we report an additive engineering strategy to realize high-performance and stable field-effect transistors (FETs) based on 3D formamidinium tin iodide (FASnI3) films. By comparatively studying the modification effects of two additives, i.e., phenethylammonium iodide and 4-fluorophenylethylammonium iodide via combined experimental and theoretical investigations, we unambiguously point out the general effects of phenethylammonium (PEA) and its fluorinated derivative (FPEA) in enhancing crystallization of FASnI3 films and the unique role of fluorination in reducing structural defects, suppressing oxidation of Sn2+ and blocking oxygen and water involved defect reactions. The optimized FPEA-modified FASnI3 FETs reach a record high field-effect mobility of 15.1 cm2/(V·s) while showing negligible hysteresis. The devices exhibit less than 10% and 3% current variation during over 2 h continuous bias stressing and 4200-cycle switching test, respectively, representing the best stability achieved so far for all Sn-based FETs.</p
Phase Modulation of (1T-2H)-MoSe2/TiC-C Shell/Core Arrays via Nitrogen Doping for Highly Efficient Hydrogen Evolution Reaction
Tailoring molybdenum selenide electrocatalysts with tunable phase and morphology is of great importance for advancement of hydrogen evolution reaction (HER). In this work, phaseâ and morphologyâmodulated Nâdoped MoSe2/TiCâC shell/core arrays through a facile hydrothermal and postannealing treatment strategy are reported. Highly conductive TiCâC nanorod arrays serve as the backbone for MoSe2 nanosheets to form highâquality MoSe2/TiCâC shell/core arrays. Impressively, continuous phase modulation of MoSe2 is realized on the MoSe2/TiCâC arrays. Except for the pure 1TâMoSe2 and 2HâMoSe2, mixed (1Tâ2H)âMoSe2 nanosheets are achieved in the NâMoSe2 by N doping and demonstrated by spherical aberration electron microscope. Plausible mechanism of phase transformation and different doping sites of N atom are proposed via theoretical calculation. The much smaller energy barrier, longer HSe bond length, and diminished bandgap endow NâMoSe2/TiCâC arrays with substantially superior HER performance compared to 1T and 2H phase counterparts. Impressively, the designed NâMoSe2/TiCâC arrays exhibit a low overpotential of 137 mV at a large current density of 100 mA cmâ2, and a small Tafel slope of 32 mV decâ1. Our results pave the way to unravel the enhancement mechanism of HER on 2D transition metal dichalcogenides by N doping
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