2,856 research outputs found

    Majorana neutrino signals at Belle-II and ILC

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    For some theoretical and experimental considerations, the relatively light Majorana neutrinos at the GeV scale have been attracting some interest. In this article we consider a scenario with only one Majorana neutrino NN, negligible mixing with the active neutrinos νL\nu_{L}, where the Majorana neutrino interactions could be described in a model independent approach based on an effective theory. Under such a framework, we particularly study the feasibility of observing the NN with mass in the range 0-30 GeV via the process e^+ e^- \to \nu N \to\gamma + \slashed E in the future Belle-II and ILC experiments. The results show that it is unpromising for Belle-II to observe the signal, while ILC may easily make a discovery for the Majorana neutrino.Comment: 14 pages, 7 figures, 2 table

    Cell aggregation induces phosphorylation of PECAM-1 and Pyk2 and promotes tumor cell anchorage-independent growth

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    <p>Abstract</p> <p>Background</p> <p>Apoptosis caused by inadequate or inappropriate cell-matrix interactions is defined as anoikis. Although transformed cells are known to be anoikis-resistant, the underlying mechanisms have not been well understood. We investigated the mechanisms of anoikis resistance of tumor cells.</p> <p>Results</p> <p>We observed that cell aggregation in suspension promoted cell survival and proliferation. We demonstrated a correlation between tumor cell aggregation in suspension and cell growth in soft agar. Analysis of tyrosine kinase-mediated cell survival and growth signaling pathways revealed increased levels of tyrosine-phosphorylation of PECAM-1 and Pyk2 in cell aggregates. We also showed that PECAM-1 and Pyk2 physically interact with each other, and that PECAM-1 carrying a deletion of exons 11-16 could no longer bind to Pyk2. Furthermore, RNA interference-mediated reduction of Pyk2 and PECAM-1 protein levels reduced cell aggregation and inhibited the growth of tumor cells in soft agar.</p> <p>Conclusions</p> <p>The data demonstrated that Pyk2 and PECAM-1 were critical mediators of both anchorage-independent growth and anoikis resistance in tumor cells.</p

    Precise QCD predictions on top quark pair production mediated by massive color octet vector boson at hadron colliders

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    We present a theoretical framework for systematically calculating next-to-leading order (NLO) QCD effects to various experimental observables in models with massive COVB in a model independent way at hadron colliders. Specifically, we show the numerical results for the NLO QCD corrections to total cross sections, invariant mass distribution and AFB of top quark pairs production mediated by a massive COVB in both the fixed scale (top quark mass) scheme and the dynamical scale (top pair invariant mass) scheme. Our results show that the NLO QCD calculations in the dynamical scale scheme is more reasonable than the fixed scheme and the naive estimate of the NLO effects by simple rescaling of the LO results with the SM NLO K-factor is not appropriate.Comment: 6 pages, 5 figures, 2 tables; version published in EPJ

    The ρ\rho-meson longitudinal leading-twist distribution amplitude

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    In the present paper, we suggest a convenient model for the vector ρ\rho-meson longitudinal leading-twist distribution amplitude ϕ2;ρ\phi_{2;\rho}^\|, whose distribution is controlled by a single parameter B2;ρB^\|_{2;\rho}. By choosing proper chiral current in the correlator, we obtain new light-cone sum rules (LCSR) for the BρB\to\rho TFFs A1A_1, A2A_2 and VV, in which the δ1\delta^1-order ϕ2;ρ\phi_{2;\rho}^\| provides dominant contributions. Then we make a detailed discussion on the ϕ2;ρ\phi_{2;\rho}^\| properties via those BρB\to\rho TFFs. A proper choice of B2;ρB^\|_{2;\rho} can make all the TFFs agree with the lattice QCD predictions. A prediction of Vub|V_{\rm ub}| has also been presented by using the extrapolated TFFs, which indicates that a larger B2;ρB^{\|}_{2;\rho} leads to a larger Vub|V_{\rm ub}|. To compare with the BABAR data on Vub|V_{\rm ub}|, the longitudinal leading-twist DA ϕ2;ρ\phi_{2;\rho}^\| prefers a doubly-humped behavior.Comment: 7 pages, 3 figures. Discussions improved and references updated. To be published in Phys.Lett.
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