11,702 research outputs found

    A Mediator Lost in the War on Cancer

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    An unexpected role for a Mediator subunit, MED12, in resistance to multiple anticancer agents is revealed by Huang et al. Loss of MED12 confers drug resistance by activating transforming growth factor β (TGF-β) signaling. Inhibition of the TGF-β pathway resensitizes cells to therapeutic drugs, suggesting a new combinatorial cancer treatment

    The Algebraic Structure of the gl(n∣m)gl(n|m) Color Calogero-Sutherland Models

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    We extend the study on the algebraic structure of the su(n)su(n) color Calogero-Sutherland models to the case of gl(n∣m)gl(n|m) color CS model and show that the generators of the super-Yangian Y(gl(n∣m))Y(gl(n|m)) can be obtained from two gl(n∣m)gl(n|m) loop algebras. Also, a super W∞W_{\infty} algebra for the SUSY CS model is constructed.Comment: LaTeX, 13 page

    Constraints on anomalous quartic gauge couplings via WγjjW\gamma jj production at the LHC

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    The vector boson scattering at the Large Hadron Collider (LHC) is sensitive to anomalous quartic gauge couplings (aQGCs). In this paper, we investigate the aQGC contribution to Wγjj W \gamma jj production at the LHC with s=13\sqrt{s}=13 TeV in the context of an effective field theory (EFT). The unitarity bound is applied as a cut on the energy scale of this production process, which is found to have significant suppressive effects on the signals. To enhance the statistical significance, we analyse the kinematic and polarization features of the aQGC signals in detail. We find that the polarization effects induced by the aQGCs are unique and can discriminate the signals from the SM backgrounds well. With the proposed event selection strategy, we obtain the constraints on the coefficients of dimension-8 operators with current luminosity. The results indicate that the process pp→Wγjjpp \to W \gamma jj is powerful for searching for the OM2,3,4,5O_{M_{2,3,4,5}} and OT5,6,7O_{T_{5,6,7}} operators.Comment: 29 pages, 11 figures, 7 tables, to be published in Chinese Physics
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