Gravitational Effects of Rotating Bodies

We study two type effects of gravitational field on mechanical gyroscopes (i.e. rotating extended bodies). The first depends on special relativity and equivalence principle. The second is related to the coupling (i.e. a new force) between the spins of mechanical gyroscopes, which would violate the equivalent principle. In order to give a theoretical prediction to the second we suggest a spin-spin coupling model for two mechanical gyroscopes. An upper limit on the coupling strength is then determined by using the observed perihelion precession of the planet's orbits in solar system. We also give predictions violating the equivalence principle for free-fall gyroscopes .Comment: LaTex, 6 page

A spin-rotation mechanism of Einstein-de Haas effect based on a ferromagnetic disk

Spin-rotation coupling (SRC) is a fundamental phenomenon that connects electronic spins with the rotational motion of a medium. We elucidate the Einstein-de Haas (EdH) effect and its inverse with SRC as the microscopic mechanism using the dynamic spin-lattice equations derived by elasticity theory and Lagrangian formalism. By applying the coupling equations to an iron disk in a magnetic field, we exhibit the transfer of angular momentum and energy between spins and lattice, with or without damping. The timescale of the angular momentum transfer from spins to the entire lattice is estimated by our theory to be on the order of 0.01 ns, for the disk with a radius of 100 nm. Moreover, we discover a linear relationship between the magnetic field strength and the rotation frequency, which is also enhanced by a higher ratio of Young's modulus to Poisson's coefficient. In the presence of damping, we notice that the spin-lattice relaxation time is nearly inversely proportional to the magnetic field. Our explorations will contribute to a better understanding of the EdH effect and provide valuable insights for magneto-mechanical manufacturing

Delisheng, a Chinese medicinal compound, exerts anti-proliferative and pro-apoptotic effects on HepG2 cells through extrinsic and intrinsic pathways

The anti-proliferative, cytotoxic and apoptogenic activities of delisheng, a Chinese medicinal compound, has been investigated. In this study, the hepatocarcinoma cell line (HepG2) and the liver cell line (L-02) were exposed to delisheng (6.25, 50 and 100 μl/ml). Delisheng suppressed the proliferation and viability of normal liver L-02 cells slightly, but strongly inhibited the proliferation and viability of hepatocarcinoma HepG2 cells. The flow cytometric analysis of HepG2 cells demonstrated that delisheng primarily arrested the HepG2 cells at the G1 phase of the cell cycle. Annexin V-FITC/PI staining corroborates the apoptogenic nature of delisheng on HepG2 cells. The anti-proliferative and pro-apoptotic effect of delisheng in HepG2 cells was associated with changes in the Bcl-2/Bax ratio and the induction of caspase-mediated apoptosis. Upregulation of DR5 expression was observed in HepG2 cells after treatment with delisheng. The findings from the present study suggest that delisheng has selective cytotoxic activities against HepG2 cells. Delisheng triggered time- and dose-dependent apoptosis in HepG2 cells by activating the mitochondria-mediated and death receptor-mediated apoptotic pathways

Practical Quantum Simulation of Non-Hermitian Dynamics

Non-Hermitian quantum systems have recently attracted considerable attentions due to their exotic properties. Though many experimental realizations of non-Hermitian systems have been reported, the non-Hermiticity usually resorts to the hard-to-control environments. An alternative approach is to use quantum simulation with the closed system, whereas how to simulate general non-Hermitian Hamiltonian dynamics remains a great challenge. To tackle this problem, we propose a protocol by combining a dilation method with the variational quantum algorithm. The dilation method is used to transform a non-Hermitian Hamiltonian into a Hermitian one through an exquisite quantum circuit, while the variational quantum algorithm is for efficiently approximating the complex entangled gates in this circuit. As a demonstration, we apply our protocol to simulate the dynamics of an Ising chain with nonlocal non-Hermitian perturbations, which is an important model to study quantum phase transition at nonzero temperatures. The numerical simulation results are highly consistent with the theoretical predictions, revealing the effectiveness of our protocol. The presented protocol paves the way for practically simulating general non-Hermitian dynamics in the multi-qubit case.Comment: 9 pages, 5 figure

Control-enhanced quantum metrology under Markovian noise

Quantum metrology is supposed to significantly improve the precision of parameter estimation by utilizing suitable quantum resources. However, the predicted precision can be severely distorted by realistic noises. Here, we propose a control-enhanced quantum metrology scheme to defend against these noises for improving the metrology performance. Our scheme can automatically alter the parameter encoding dynamics with adjustable controls, thus leading to optimal resultant states that are less sensitive to the noises under consideration. As a demonstration, we numerically apply it to the problem of frequency estimation under several typical Markovian noise channels. Through comparing our control-enhanced scheme with the standard scheme and the ancilla-assisted scheme, we show that our scheme performs better and can improve the estimation precision up to around one order of magnitude. Furthermore, we conduct a proof-of-principle experiment in nuclear magnetic resonance system to verify the effectiveness of the proposed scheme. The research here is helpful for current quantum platforms to harness the power of quantum metrology in realistic noise environments.Comment: 9 pages, 5 figure

Measuring Quantum Entanglement from Local Information by Machine Learning

Entanglement is a key property in the development of quantum technologies and in the study of quantum many-body simulations. However, entanglement measurement typically requires quantum full-state tomography (FST). Here we present a neural network-assisted protocol for measuring entanglement in equilibrium and non-equilibrium states of local Hamiltonians. Instead of FST, it can learn comprehensive entanglement quantities from single-qubit or two-qubit Pauli measurements, such as R\'enyi entropy, partially-transposed (PT) moments, and coherence. It is also exciting that our neural network is able to learn the future entanglement dynamics using only single-qubit traces from the previous time. In addition, we perform experiments using a nuclear spin quantum processor and train an adoptive neural network to study entanglement in the ground and dynamical states of a one-dimensional spin chain. Quantum phase transitions (QPT) are revealed by measuring static entanglement in ground states, and the entanglement dynamics beyond measurement time is accurately estimated in dynamical states. These precise results validate our neural network. Our work will have a wide range of applications in quantum many-body systems, from quantum phase transitions to intriguing non-equilibrium phenomena such as quantum thermalization.Comment: 5 pages, 4 figures. All comments are welcom

A Novel Lipopolysaccharide Recognition Mechanism Mediated by Internalization in Teleost Macrophages

Macrophages in teleosts are less sensitive to lipopolysaccharide (LPS) compared to mammals. The functional equivalent of the mammalian LPS surface receptor in teleost macrophages for the pro-inflammatory response is either non-existent or replaced by negative regulation. LPS signaling in teleost macrophages remains unclear. Here, we found a scavenger receptor class B 2a (PaSRB2a) that played a crucial role in LPS signaling in teleost macrophages. The internalization of LPS and subsequent pro-inflammatory responses in macrophages were mediated by PaSRB2a, which is a novel isoform of the mammalian SRB2 gene. LPS internalization by PaSRB2a is dependent on its C-terminal intracellular domain. Following LPS internalization, it interacts with the ayu intracellular receptors nucleotide-binding oligomerization domain protein 1 (PaNOD1) and PaNOD2. Moreover, LPS pre-stimulation with sub-threshold concentrations reduced the effect of secondary LPS treatment on pro-inflammatory responses that were mediated by PaSRB2a. The pro-inflammatory responses in LPS-treated ayu were down-regulated upon PaSRB2a knockdown by lentivirus siRNA delivery. In grass carp and spotted green pufferfish, SRB2a also mediated LPS internalization and pro-inflammatory responses. Our work identifies a novel LPS signaling pathway in teleosts that differs from those in mammals, and contributes to our understanding of the evolution of pathogen recognition in vertebrates