47,791 research outputs found
Complete gradient-LC-ESI system on a chip for protein analysis
This paper presents the first fully integrated gradient-elution liquid chromatography-electrospray ionization (LC-ESI) system on a chip. This chip integrates a pair of high-pressure gradient pumps, a sample injection pump, a passive mixer, a packed separation column, and an ESI nozzle. We also present the successful on-chip separation of protein digests by reverse phase (RP)-LC coupled with on-line mass spectrometer (MS) analysis
GraphSE: An Encrypted Graph Database for Privacy-Preserving Social Search
In this paper, we propose GraphSE, an encrypted graph database for online
social network services to address massive data breaches. GraphSE preserves
the functionality of social search, a key enabler for quality social network
services, where social search queries are conducted on a large-scale social
graph and meanwhile perform set and computational operations on user-generated
contents. To enable efficient privacy-preserving social search, GraphSE
provides an encrypted structural data model to facilitate parallel and
encrypted graph data access. It is also designed to decompose complex social
search queries into atomic operations and realise them via interchangeable
protocols in a fast and scalable manner. We build GraphSE with various
queries supported in the Facebook graph search engine and implement a
full-fledged prototype. Extensive evaluations on Azure Cloud demonstrate that
GraphSE is practical for querying a social graph with a million of users.Comment: This is the full version of our AsiaCCS paper "GraphSE: An
Encrypted Graph Database for Privacy-Preserving Social Search". It includes
the security proof of the proposed scheme. If you want to cite our work,
please cite the conference version of i
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