DYNAFED: Tackling Client Data Heterogeneity with Global Dynamics

The Federated Learning (FL) paradigm is known to face challenges under heterogeneous client data. Local training on non-iid distributed data results in deflected local optimum, which causes the client models drift further away from each other and degrades the aggregated global model's performance. A natural solution is to gather all client data onto the server, such that the server has a global view of the entire data distribution. Unfortunately, this reduces to regular training, which compromises clients' privacy and conflicts with the purpose of FL. In this paper, we put forth an idea to collect and leverage global knowledge on the server without hindering data privacy. We unearth such knowledge from the dynamics of the global model's trajectory. Specifically, we first reserve a short trajectory of global model snapshots on the server. Then, we synthesize a small pseudo dataset such that the model trained on it mimics the dynamics of the reserved global model trajectory. Afterward, the synthesized data is used to help aggregate the deflected clients into the global model. We name our method Dynafed, which enjoys the following advantages: 1) we do not rely on any external on-server dataset, which requires no additional cost for data collection; 2) the pseudo data can be synthesized in early communication rounds, which enables Dynafed to take effect early for boosting the convergence and stabilizing training; 3) the pseudo data only needs to be synthesized once and can be directly utilized on the server to help aggregation in subsequent rounds. Experiments across extensive benchmarks are conducted to showcase the effectiveness of Dynafed. We also provide insights and understanding of the underlying mechanism of our method

Li2NiO2F a new oxyfluoride disordered rocksalt cathode material

Lithium-rich disordered rocksalts such as Li1.3Nb0.3Mn0.4O2 and Li2MnO2F are being investigated as high energy density cathodes for next generation Li-ion batteries. They can support the (de) lithiation of lithium ions over large compositional ranges while preserving the same overall structure. Here, we present a new Ni-rich oxyfluoride cathode, Li2NiO2F, with a disordered rocksalt structure. Li2NiO2F and can deliver a discharge capacity of 200 mAh g−1 at an average voltage of 3.2 V

Corrigendum to: The TianQin project: current progress on science and technology

In the originally published version, this manuscript included an error related to indicating the corresponding author within the author list. This has now been corrected online to reflect the fact that author Jun Luo is the corresponding author of the article

Effective Bilevel Optimization via Minimax Reformulation

Bilevel optimization has found successful applications in various machine learning problems, including hyper-parameter optimization, data cleaning, and meta-learning. However, its huge computational cost presents a significant challenge for its utilization in large-scale problems. This challenge arises due to the nested structure of the bilevel formulation, where each hyper-gradient computation necessitates a costly inner optimization procedure. To address this issue, we propose a reformulation of bilevel optimization as a minimax problem, effectively decoupling the outer-inner dependency. Under mild conditions, we show these two problems are equivalent. Furthermore, we introduce a multi-stage gradient descent and ascent (GDA) algorithm to solve the resulting minimax problem with convergence guarantees. Extensive experimental results demonstrate that our method outperforms state-of-the-art bilevel methods while significantly reducing the computational cost.Comment: Typos and intended inclusion of additional experiment

Flood Effect on Groundwater Recharge on a Typical Silt Loam Soil

Floods are of great concern as the global climate changes, and investigations of flood water infiltration and groundwater recharge are important for water resource management worldwide, especially under conditions of global climate changes. However, information on the relationship between the flood water and groundwater recharge is limited. The objective of this study was to determine the relationship between the flood water depth and the height of groundwater rise using lysimeters and numerical modeling in the floodplain of the Tarim River in northwestern China. The experimental results suggested that the rise in height of the groundwater table was closely related to the flood water ponding depth, and the groundwater depth decreased quickly after flooding due to the high infiltration rate of water originating at the Tarim River. The water table falling velocity was significantly less than the water table rising velocity. If the initial groundwater table was deeper, the variation in the water table rise depth was smaller and the water table falling velocity was slower. The numerical simulation results showed good agreement with the observed data, with a determination coefficient (R2) of 0.87 and a root mean square error (RMSE) of 63.91 cm. A good relationship (R2 = 0.789) between the initial groundwater table depth (H0), initial soil water content (W0), flood water depth (h), and height of the water table rise (H) was established. Considering that natural and artificial flood frequencies are related to flood time interval (dt), a relationship (R2 = 0.892) was developed between them. These results can enhance the understanding of flood recharge characteristics in the floodplains of inland rivers

Effect of continuous equal channel angular pressing on microstructure and properties of Al-Ti-C alloy

The Al-Ti-C alloy was extruded in multiple passes in a continuous manner by continuous equal channel angular pressing process. Through observation of the microstructure evolution, the mechanism of grain refinement and changes in mechanical properties were discussed.The results show that continuous equal channel angular pressing process can effectively refine the microstructure of Al-Ti-C alloy, and the grain size is reduced to about 1 μm.The deformation induction is the most important grain refinement mechanism in the deformation process.The accumulation of high density dislocations causes cracks at the interface between the Al matrix and TiAl3 and voids inside the TiAl3. The cracks further propagate through the entire TiAl3 particles, ultimately leading to the refinement of the second phase TiAl3 structure.At the same time, the pinning mechanism and shearing mechanism of the fine second phase TiAl3 structure promote the refinement of the Al matrix.After one pass of continuous equal channel angular pressing, the hardness of the alloy increases most obviously, which is 59.2% higher than that of the original state.With the increase of the number of extrusion passes, the increasing trend of hardness slows down, the plasticity of the alloy decreases, and toughness increases

Space Debris Laser Ranging with range-gate-free Superconducting Nanowire Single-Photon Detector

Space Debris Laser Ranging (DLR) is a technique to measure range to defunct satellites, rocket bodies or other space targets in orbits around Earth. The analysis shows that one of the reasons for the low success probability of DLR is the inaccurate orbital prediction of targets. Then it is proposed to use the Superconducting Nanowire Single-Photon Detector (SNSPD) running in automatic-recoverable range-gate-free mode, in which case, the effect of the accuracy of the target’s orbital prediction on the success probability of DLR is greatly reduced. In this way, 249 space debris were successfully detected and 532 passes of data were obtained. The smallest target detected was the space-debris (902) with an orbital altitude of about 1000 km and a Radar Cross Section (RCS) of 0.0446 m2. The farthest target detected was the space-debris (12,445) with a large elliptical orbit and an RCS of 18.2505 m2, of which the range of the normal point (NPT) of the measured arc-segment on January 27, 2019 was 6260.805 km

Identification of a novel M-superfamily conotoxin with the ability to enhance tetrodotoxin sensitive sodium currents

In this work, a novel M-superfamily conotoxin, designated lt3a, was purified from the crude venom of Conus litteratus. Combined with peptide sequencing, MALDI-TOF mass spectrometry and cDNA cloning techniques, the amino acid sequence of lt3a was supposed to be DgammaCCgamma OQWCDGACDCCS, where O is hydroxyproline and gamma is carboxyglutamate. The Cys framework of lt3a (-CC-C-C-CC-) is similar to that of psi-, mu-, kappaM-conotoxins, which are representatives of M-conotoxins. Peptide lt3a is categorized into M1 branch based on the number of residues in the last Cys loop. Whole cell patch-clamp study on adult rat dorsal root ganglion neurons indicated that lt3a could enhance tetrodotoxin-sensitive sodium currents. This is a previously unknown function of M-superfamily conotoxins

A metal ions-mediated natural small molecules carrier-free injectable hydrogel achieving laser-mediated photo-Fenton-like anticancer therapy by synergy apoptosis/cuproptosis/anti-inflammation

Tumor microenvironment (TME) plays an important role in the tumorigenesis, proliferation, invasion and metastasis. Thereby developing synergistic anticancer strategies with multiple mechanisms are urgent. Copper is widely used in the treatment of tumor chemodynamic therapy (CDT) due to its excellent laser-mediated photo-Fenton-like reaction. Additionally, copper can induce cell death through cuproptosis, which is a new modality different from the known death mechanisms and has great promise in tumor treatment. Herein, we report a natural small molecules carrier-free injectable hydrogel (NCTD Gel) consisted of Cu2+-mediated self-assembled glycyrrhizic acid (GA) and norcantharidin (NCTD), which are mainly governed by coordination and hydrogen bonds. Under 808 nm laser irradiation, NCTD Gel can produce reactive oxygen species (ROS), consume glutathione (GSH) and overcome hypoxia in TME, leading to synergistically regulate TME via apoptosis, cuproptosis and anti-inflammation. In addition, NCTD Gel's CDT display high selectivity and good biocompatibility as it relies on the weak acidity and H2O2 overexpression of TME. Notably, NCTD Gel's components are originated from clinical agents and its preparation process is easy, green and economical, without any excipients. This study provides a new carrier-free hydrogel synergistic antitumor strategy, which has a good prospect in industrial production and clinical transformation