Draft Genome Sequence of a Potential Nitrate-Dependent Fe(II)-Oxidizing Bacterium, Aquabacterium parvum B6

Aquabacterium parvum B6 is a potential nitrate-dependent Fe(II)-oxidizing bacterium. The genes related to its denitrifying mechanism and iron metabolisms were unknown. We present the draft genome of Aquabacterium parvum B6, which could provide further insight into the nitrate-dependent Fe(II)-oxidizing mechanism of strain B6

Traveling Wave Solutions for Planar Lattice Differential Systems with Applications to Neural Networks

AbstractWe obtain some existence results for traveling wave fronts and slowly oscillatory spatially periodic traveling waves of planar lattice differential systems with delay. Our approach is via Schauder's fixed-point theorem for the existence of traveling wave fronts and via S1-degree and equivarant bifurcation theory for the existence of periodic traveling waves. As examples, the obtained abstract results will be applied to a model arising from neural networks and explicit conditions for traveling wave fronts and global continuation of periodic waves will be obtained

Clinical features of X linked juvenile retinoschisis in Chinese families associated with novel mutations in the RS1 gene

Purpose: To describe the clinical phenotype of X linked juvenile retinoschisis (XLRS) in 12 Chinese families with 11 different mutations in the XLRS1 (RS1) gene. Methods: Complete ophthalmic examinations were carried out in 29 affected males (12 probands), 38 heterozygous females carriers, and 100 controls. The coding regions of the RS1 gene that encodes retinoschisin were amplified by polymerase chain reaction and directly sequenced. Results: Of the 29 male participants, 28 (96.6%) displayed typical foveal schisis. Eleven different RS1 mutations were identified in 12 families; four of these mutations, two frameshift mutations (26 del T of exon 1 and 488 del G of exon 5), and two missense mutations (Asp145His and Arg156Gly) of exon 5, had not been previously described. One non-disease-related polymorphism (NSP): 576C to T (Pro192Pro) change was also newly reported herein. We compared genotypes and observed more severe clinical features in families with the following mutations: frameshift mutation (26 del T) of exon 1, the splice donor site mutation (IVS1+2T to C),or Arg102Gln, Arg209His, and Arg213Gln mutations. Conclusions: Severe XLRS phenotypes are associated with the frameshift mutation 26 del T, splice donor site mutation (IVS1+2T to C), and Arg102Gln, Asp145His, Arg209His, and Arg213Gln mutations. The wide variability in the phenotype in Chinese patients with XLRS and different mutations in the RS1 gene is described. Identification of mutations in the RS1 gene and expanded information on clinical manifestations will facilitate early diagnosis, appropriate early therapy, and genetic counseling regarding the prognosis of XLRS.Biochemistry & Molecular BiologyOphthalmologySCI(E)PubMed12ARTICLE88804-8121

Effect of chromatic dispersion induced chirp on the temporal coherence property of individual beam from spontaneous four wave mixing

Temporal coherence of individual signal or idler beam, determined by the spectral correlation property of photon pairs, is important for realizing quantum interference among independent sources. To understand the effect of chirp on the temporal coherence property, two series of experiments are investigated by introducing different amount of chirp into either the pulsed pump or individual signal (idler) beam. In the first one, based on spontaneous four wave mixing in a piece of optical fiber, the intensity correlation function of the filtered individual signal beam, which characterizes the degree of temporal coherence, is measured as a function of the chirp of pump. The results demonstrate that the chirp of pump pulses decreases the degree of temporal coherence. In the second one, a Hong-Ou-Mandel type two-photon interference experiment with the signal beams generated in two different fibers is carried out. The results illustrate that the chirp of individual beam does not change the temporal coherence degree, but affect the temporal mode matching. To achieve high visibility, apart from improving the coherence degree by minimizing the chirp of pump, mode matching should be optimized by managing the chirps of individual beams.Comment: 17pages, 4figure

Prognostic factors and outcomes of early-stage small cell neuroendocrine carcinoma of the cervix: 37 cases from a single center

Background The objective of this study is to investigate small cell neuroendocrine carcinoma of the cervix (SCCC), using a retrospective clinicopathological characteristic and treatment approach. Method We retrospectively analyzed cases of early-stage SCCC, identified between 2006 and 2016, in women who received radical surgery and adjuvant chemotherapy with or without radiotherapy. Kaplan–Meier and one-way ANOVA analyses were performed. Result A total of 37 cases of SCCC are presented in this study, of which 21 had stage IB1 SCCC, 12 had stage IB2, 3 had stage IIA1, and 1 had stage IIA2. All patients were treated with radical surgery and adjuvant chemotherapy, specifically, 26 with radical surgery followed by adjuvant chemotherapy plus radiation and 11 with neoadjuvant chemotherapy (NACT) followed by radical surgery. After a median follow-up time of 27 months (range, 8–115 months), the 2-year and 5-year disease-free survival rate for all patients was 51.9% and 34.1%, respectively, and the overall survival rate was 60.3% and 38.6%, respectively. Univariate analysis showed that International Federation of Gynecology and Obstetrics (FIGO) stage and tumor size may be a predictor of a poor prognosis. NACT and adjuvant radiation did not improve survival over adjuvant chemotherapy alone but should not be a significant independent prognostic factor for survival. Conclusion Even in patients with early-stage SCCC, the prognosis is poor, although FIGO stage and tumor size may act as surrogate factors prognostic of survival

An all fiber source of frequency entangled photon pairs

We present an all fiber source of frequency entangled photon pairs by using four wave mixing in a Sagnac fiber loop. Special care is taken to suppress the impurity of the frequency entanglement by cooling the fiber and by matching the polarization modes of the photon pairs counter-propagating in the fiber loop. Coincidence detection of signal and idler photons, which are created in pair and in different spatial modes of the fiber loop, shows the quantum interference in the form of spatial beating, while the single counts of the individual signal (idler) photons keep constant. When the production rate of photon pairs is about 0.013 pairs/pulse, the envelope of the quantum interference reveals a visibility of $(95\pm 2)$, which is close to the calculated theoretical limit 97.4%Comment: 11 pages, 6 figures, to appear in Phys. Rev.

Stoichiometry and stable isotopes of plants and their response to environmental factors in boreal peatland, Northeast China

The alterations of plant composition and diversity pose a threat to the stability of the carbon pool in boreal peatland under climate change. We collected the samples of three plant functional types (deciduous shrubs, evergreen shrubs, and sedge) in seven permafrost peatlands of the Great Hing’an Mountains, China, and measured the properties of total carbon (TC), nitrogen (TN), and phosphorus (TP), their stoichiometric ratios (C:N, C:P, and N:P), and the stable isotope values (δ13C and δ15N) of six tissues (ranging from leaves to roots). For TC, TN, and TP, the contents had an average of 470.69 ± 1.56, 8.03 ± 0.23, and 1.71 ± 0.61 mg·g−1, respectively. TC contents of sedge were lower than those of shrubs for the whole plant. The allocations of N and P to shrub leaves were higher than to stems and roots. There was a similar trend of TN and TP contents, and stoichiometric ratios from leaves to roots between deciduous shrubs and evergreen shrubs. Shrubs and sedge have similar C: N in leaves and fine roots, while leaves of sedge C:P and N:P ratios were higher than shrubs, mainly showed that sedge is N and P co-limitation and shrubs are N limitation. The values of δ13C and δ15N were significantly higher in leaves and roots of sedge than those of shrubs, which means shrubs have higher nutrient acquisition strategies. These results support the shrubs are expanding in the boreal peatland under climate warming through nutrient competition. TC contents of all deciduous shrubs and sedge tissues were positively linear correlated to MAT and the values of δ13C and δ15N in sedge had significant relationships with MAT and MAP. Our results imply warming can increase plant photosynthesis in boreal peatland, and sedge was more sensitive to climate change. These findings would be helpful to understanding the responses of different plant tissues to climate changes in permafrost peatland