Randomness Quality of CI Chaotic Generators: Applications to Internet Security

Due to the rapid development of the Internet in recent years, the need to find new tools to reinforce trust and security through the Internet has became a major concern. The discovery of new pseudo-random number generators with a strong level of security is thus becoming a hot topic, because numerous cryptosystems and data hiding schemes are directly dependent on the quality of these generators. At the conference Internet`09, we have described a generator based on chaotic iterations, which behaves chaotically as defined by Devaney. In this paper, the proposal is to improve the speed and the security of this generator, to make its use more relevant in the Internet security context. To do so, a comparative study between various generators is carried out and statistical results are given. Finally, an application in the information hiding framework is presented, to give an illustrative example of the use of such a generator in the Internet security field.Comment: 6 pages,6 figures, In INTERNET'2010. The 2nd Int. Conf. on Evolving Internet, Valencia, Spain, pages 125-130, September 2010. IEEE Computer Society Press Note: Best Paper awar

Systematic Curation of miRBase Annotation Using Integrated Small RNA High-Throughput Sequencing Data for C. elegans and Drosophila

MicroRNAs (miRNAs) are a class of 20–23 nucleotide small RNAs that regulate gene expression post-transcriptionally in animals and plants. Annotation of miRNAs by the miRNA database (miRBase) has largely relied on computational approaches. As a result, many miRBase entries lack experimental validation, and discrepancies between miRBase annotation and actual miRNA sequences are often observed. In this study, we integrated the small RNA sequencing (smRNA-seq) datasets in Caenorhabditis elegans and Drosophila melanogaster and devised an analytical pipeline coupled with detailed manual inspection to curate miRNA annotation systematically in miRBase. Our analysis reveals 19 (17.0%) and 51 (31.3%) miRNAs entries with detectable smRNA-seq reads have mature sequence discrepancies in C. elegans and D. melanogaster, respectively. These discrepancies frequently occur either for conserved miRNA families whose mature sequences were predicted according to their homologous counterparts in other species or for miRNAs whose precursor miRNA (pre-miRNA) hairpins produce an abundance of multiple miRNA isoforms or variants. Our analysis shows that while Drosophila pre-miRNAs, on average, produce less than 60% accurate mature miRNA reads in addition to their 5′ and 3′ variant isoforms, the precision of miRNA processing in C. elegans is much higher, at over 90%. Based on the revised miRNA sequences, we analyzed expression patterns of the more conserved (MC) and less conserved (LC) miRNAs and found that, whereas MC miRNAs are often co-expressed at multiple developmental stages, LC miRNAs tend to be expressed specifically at fewer stages

Shelter: Smartphone Bridged Socialized Body Networks for Epidemic Control

We propose using information, computing and networking innovations to tackle epidemic control challenges

A Schur's type volume comparison theorem

In this paper, inspired by Schur's comparison theorem about curves in Euclidean space, we mainly provide a Schur's type volume comparison theorem, which is about the volumes of the boundaries of open balls in a complete $n$-dimensional Riemannian manifold with Ricci$\geq (n-1)k$.Comment: 12 page