714 research outputs found
Realistic Full-Body Tracking from Sparse Observations via Joint-Level Modeling
To bridge the physical and virtual worlds for rapidly developed VR/AR
applications, the ability to realistically drive 3D full-body avatars is of
great significance. Although real-time body tracking with only the head-mounted
displays (HMDs) and hand controllers is heavily under-constrained, a carefully
designed end-to-end neural network is of great potential to solve the problem
by learning from large-scale motion data. To this end, we propose a two-stage
framework that can obtain accurate and smooth full-body motions with the three
tracking signals of head and hands only. Our framework explicitly models the
joint-level features in the first stage and utilizes them as spatiotemporal
tokens for alternating spatial and temporal transformer blocks to capture
joint-level correlations in the second stage. Furthermore, we design a set of
loss terms to constrain the task of a high degree of freedom, such that we can
exploit the potential of our joint-level modeling. With extensive experiments
on the AMASS motion dataset and real-captured data, we validate the
effectiveness of our designs and show our proposed method can achieve more
accurate and smooth motion compared to existing approaches.Comment: Accepted to ICCV 2023. Project page:
https://zxz267.github.io/AvatarJL
Effectiveness of multi-drug regimen chemotherapy treatment in osteosarcoma patients: a network meta-analysis of randomized controlled trials
Abstract Background Osteosarcoma is the most common malignant bone tumour. Due to the high metastasis rate and drug resistance of this disease, multi-drug regimens are necessary to control tumour cells at various stages of the cell cycle, eliminate local or distant micrometastases, and reduce the emergence of drug-resistant cells. Many adjuvant chemotherapy protocols have shown different efficacies and controversial results. Therefore, we classified the types of drugs used for adjuvant chemotherapy and evaluated the differences between single- and multi-drug chemotherapy regimens using network meta-analysis. Methods We searched electronic databases, including PubMed (MEDLINE), EmBase, and the Cochrane Library, through November 2016 using the keywords “osteosarcoma”, “osteogenic sarcoma”, “chemotherapy”, and “random*” without language restrictions. The major outcome in the present analysis was progression-free survival (PFS), and the secondary outcome was overall survival (OS). We used a random effect network meta-analysis for mixed multiple treatment comparisons. Results We included 23 articles assessing a total of 5742 patients in the present systematic review. The analysis of PFS indicated that the T12 protocol (including adriamycin, bleomycin, cyclophosphamide, dactinomycin, methotrexate, cisplatin) plays a more critical role in osteosarcoma treatment (surface under the cumulative ranking (SUCRA) probability 76.9%), with a better effect on prolonging the PFS of patients when combined with ifosfamide (94.1%) or vincristine (81.9%). For the analysis of OS, we separated the regimens to two groups, reflecting the disconnection. The T12 protocol plus vincristine (94.7%) or the removal of cisplatinum (89.4%) is most likely the best regimen. Conclusions We concluded that multi-drug regimens have a better effect on prolonging the PFS and OS of osteosarcoma patients, and the T12 protocol has a better effect on prolonging the PFS of osteosarcoma patients, particularly in combination with ifosfamide or vincristine. The OS analysis showed that the T12 protocol plus vincristine or the T12 protocol with the removal of cisplatinum might be a better regimen for improving the OS of patients. However, well-designed randomized controlled trials of chemotherapeutic protocols are still necessary
Mechanical Deformation Induced Continuously Variable Emission for Radiative Cooling
Passive radiative cooling drawing the heat energy of objects to the cold
outer space through the atmospheric transparent window (8 um - 13 um) is
significant for reducing the energy consumption of buildings. Daytime and
nighttime radiative cooling have been extensively investigated in the past.
However, radiative cooling which can continuously regulate its cooling
temperature, like a valve, according to human need is rarely reported. In this
study, we present a concept of reconfigurable photonic structure for the
adaptive radiative cooling by continuously varying the emission spectra in the
atmospheric window region. This is realized by the deformation of the
one-dimensional PDMS grating and the nanoparticles embedded PDMS thin film when
subjected to mechanical strain. The proposed structure reaches different
stagnation temperatures under certain strains. A dynamic exchange between two
different strains results in the fluctuation of the photonic structure's
temperature around a set temperature
Fish consumption and CHD mortality: an updated meta-analysis of seventeen cohort studies
Objective Results of studies on fish consumption and CHD mortality are inconsistent. The present updated meta-analysis was conducted to investigate the up-to-date pooling effects. Design A random-effects model was used to pool the risk estimates. Generalized least-squares regression and restricted cubic splines were used to assess the possible dose–response relationship. Subgroup analyses were conducted to examine the sources of heterogeneity. Setting PubMed and ISI Web of Science databases up to September 2010 were searched and secondary referencing qualified for inclusion in the study. Subjects Seventeen cohorts with 315 812 participants and average follow-up period of 15·9 years were identified. Results Compared with the lowest fish intake (\u3c1 serving/month or 1–3 servings/month), the pooled relative risk (RR) of fish intake on CHD mortality was 0·84 (95 % CI 0·75, 0·95) for low fish intake (1 serving/week), 0·79 (95 % CI 0·67, 0·92) for moderate fish intake (2–4 servings/week) and 0·83 (95 % CI 0·68, 1·01) for high fish intake (\u3e5 servings/week). The dose–response analysis indicated that every 15 g/d increment of fish intake decreased the risk of CHD mortality by 6 % (RR = 0·94; 95 % CI 0·90, 0·98). The method of dietary assessment, gender and energy adjustment affected the results remarkably. Conclusions Our results indicate that either low (1 serving/week) or moderate fish consumption (2–4 servings/week) has a significantly beneficial effect on the prevention of CHD mortality. High fish consumption (\u3e5 servings/week) possesses only a marginally protective effect on CHD mortality, possibly due to the limited studies included in this group
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