61 research outputs found

    Survivin, a molecular target for therapeutic interventions in squamous cell carcinoma

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    Evaluation of Composite Wire Ropes Using Unsaturated Magnetic Excitation and Reconstruction Image with Super-Resolution

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    Estimating the exact residual lifetime of wire rope involves the security of industry manufacturing, mining, tourism, and so on. In this paper, a novel testing technology was developed based on unsaturated magnetic excitation, and a fabricating prototype overcame the shortcomings of traditional detection equipment in terms of volume, sensibility, reliability, and weight. Massive artificial discontinuities were applied to examine the effectiveness of this new technology with a giant magneto resistance(GMR) sensor array, which included types of small gaps, curling wires, wide fractures, and abrasion. A resolution enhancement method, which was adopted for multiframe images, was proposed for promoting magnetic flux leakage images of a few sensors. Characteristic vectors of statistics and geometry were extracted, then we applied a radial basis function neural network to achieve a quantitative recognition rate of 91.43% with one wire-limiting error. Experimental results showed that the new device can detect defects in various types of wire rope and prolong the service life with high lift-off distance and high reliability, and the system could provide useful options to evaluate the lifetime of wire rope

    Quantitative Inspection of Remanence of Broken Wire Rope Based on Compressed Sensing

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    Most traditional strong magnetic inspection equipment has disadvantages such as big excitation devices, high weight, low detection precision, and inconvenient operation. This paper presents the design of a giant magneto-resistance (GMR) sensor array collection system. The remanence signal is collected to acquire two-dimensional magnetic flux leakage (MFL) data on the surface of wire ropes. Through the use of compressed sensing wavelet filtering (CSWF), the image expression of wire ropes MFL on the surface was obtained. Then this was taken as the input of the designed back propagation (BP) neural network to extract three kinds of MFL image geometry features and seven invariant moments of defect images. Good results were obtained. The experimental results show that nondestructive inspection through the use of remanence has higher accuracy and reliability compared with traditional inspection devices, along with smaller volume, lighter weight and higher precision

    Non-Destructive Detection of Wire Rope Discontinuities from Residual Magnetic Field Images Using the Hilbert-Huang Transform and Compressed Sensing

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    Electromagnetic methods are commonly employed to detect wire rope discontinuities. However, determining the residual strength of wire rope based on the quantitative recognition of discontinuities remains problematic. We have designed a prototype device based on the residual magnetic field (RMF) of ferromagnetic materials, which overcomes the disadvantages associated with in-service inspections, such as large volume, inconvenient operation, low precision, and poor portability by providing a relatively small and lightweight device with improved detection precision. A novel filtering system consisting of the Hilbert-Huang transform and compressed sensing wavelet filtering is presented. Digital image processing was applied to achieve the localization and segmentation of defect RMF images. The statistical texture and invariant moment characteristics of the defect images were extracted as the input of a radial basis function neural network. Experimental results show that the RMF device can detect defects in various types of wire rope and prolong the service life of test equipment by reducing the friction between the detection device and the wire rope by accommodating a high lift-off distance

    Recognition of Broken Wire Rope Based on Remanence using EEMD and Wavelet Methods

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    The magnetic flux leakage method is widely used for non-destructive testing in wire rope applications. A non-destructive testing device for wire rope based on remanence was designed to solve the problems of large volume, low accuracy, and complex operations seen in traditional devices. A wavelet denoising method based on ensemble empirical mode decomposition was proposed to reduce the system noise in broken wire rope testing. After extracting the defects image, the wavelet super-resolution reconstruction technique was adopted to improve the resolution of defect grayscale. A back propagation neural network was designed to classify defects by the feature vectors of area, rectangle, stretch length, and seven invariant moments. The experimental results show that the device was not only highly precise and sensitive, but also easy to operate; noise is effectively suppressed by the proposed filtering algorithm, and broken wires are classified by the network

    A Computationally Efficient Finite Element Pedestrian Model for Head Safety: Development and Validation

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    Head injuries are often fatal or of sufficient severity to pedestrians in vehicle crashes. Finite element (FE) simulation provides an effective approach to understand pedestrian head injury mechanisms in vehicle crashes. However, studies of pedestrian head safety considering full human body response and a broad range of impact scenarios are still scarce due to the long computing time of the current FE human body models in expensive simulations. Therefore, the purpose of this study is to develop and validate a computationally efficient FE pedestrian model for future studies of pedestrian head safety. Firstly, a FE pedestrian model with a relatively small number of elements (432,694 elements) was developed in the current study. This pedestrian model was then validated at both segment and full body levels against cadaver test data. The simulation results suggest that the responses of the knee, pelvis, thorax, and shoulder in the pedestrian model are generally within the boundaries of cadaver test corridors under lateral impact loading. The upper body (head, T1, and T8) trajectories show good agreements with the cadaver data in vehicle-to-pedestrian impact configuration. Overall, the FE pedestrian model developed in the current study could be useful as a valuable tool for a pedestrian head safety study

    Numerical reconstruction of injuries in a real world minivan-to-pedestrian collision

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    The purpose of this study was to evaluate the capability of the Total Human Model for Safety (THUMS) – pedestrian model in predicting pedestrian injuries, and to investigate pedestrian injury mechanisms in minivan collisions via numerical reconstruction of a real world minivan-to-pedestrian impact case. Methods: A typical minivan-to-pedestrian collision case was selected from the In-depth Investigation of car Accidents in Changsha (IVAC) database. The THUMS middle-size adult male FE model and a minivan front FE model were then employed to represent the case participants and injuries to the pedestrian’s lower limb, thorax and head were reconstructed. Finally, the capability of the THUMS model in predicting pedestrian injuries and pedestrian injury mechanisms in minivan collisions were analyzed through comparisons between predictions and the accident data. Results: The results show that the THUMS has a good capability in predicting pedestrian thorax injuries, but a lower prediction of leg bending moment and brain strain. The extra bull bar concentrates crash load to pedestrian’s leg and raises tibia/fibula fracture risk, thorax injuries in the struck side are mainly from direct contact at the lower chest level, lung injury in the non-struck side could be caused by inertia force from the heart. Rotational acceleration shows good match with brain strain and could be the key mechanism for concussion. Conclusions: The results suggest that further improvement in biofidelity of the THUMS model is still needed. The findings also offer basic understanding on pedestrian injury mechanisms in minivan collisions

    On multiply of sections of line bundles on compact Riemann surfaces

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    Tetrandrine slows the radiographic progression of progressive massive fibrosis in pneumoconiosis: a retrospective cohort study

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    Abstract Objective This study aims to explore the clinical effect of Tetrandrine (Tet) on progressive massive fibrosis (PMF) of pneumoconiosis. Methods This retrospective study collected 344 pneumoconiosis patients with PMF, and 127 were eligible for the final analysis, including 57 patients in the Tet group and 70 patients in the control group. The progress of imaging and lung function were compared between the two groups. Results After 13 months (median) of treatment, the size of PMF was smaller in the Tet group than that in the control group (1526 vs. 2306, p=0.001), and the size was stable in the Tet group (1568 vs. 1526, p= 0.381), while progressed significantly in the control group (2055 vs. 2306, p=0.000). The small nodule profusion and emphysema were also milder than that in the control group (6.0 vs. 7.5, p=0.046 and 8.0 vs. 12, p=0.016 respectively). Pulmonary ventilation function parameters FVC and FEV1 improved in the Tet group (3222 vs. 3301, p=0.021; 2202 vs. 2259, p=0.025 respectively) and decreased in the control group (3272 vs. 3185, p= 0.00; 2094 vs. 1981, p=0.00 respectively). FEV1/FVC was also significantly higher in the Tet group than that in the control group (68.45vs. 60.74, p=0.001). However, similar result was failed to observed for DLco%, which showed a significant decrease in both groups. Conclusion Tet has shown great potential in the treatment of PMF by slowing the progression of pulmonary fibrosis and the decline of lung function
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